Clinical trials: Postoperative; Dysfunction Following Cardiac Surgery
Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction
Effect of Coughing Exercises Versus Incentive Spirometry on Respiratory Function and Recovery in Children After Cardiac Surgery.
This study examines the effects of coughing exercises and incentive spirometry (IS) on lung function and recovery in children who undergo heart surgery.
- Conditions
- Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction, Postoperative Recovery After Cardiac Surgery
- Trial name
- CEXIS (NCT07405333)
- Testing
- Coughing Exercises, Incentive Spirometry, Standard Postoperative Care
- Where
- 4 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Postoperative Delirium, Postoperative Cognitive Dysfunction
Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool
This observational cohort study is designed to validate the CogCheck application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- CogCheck-Valid (NCT03360838)
- Testing
- CogCheck
- Where
- Switzerland
- Volunteers
- 475 people
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Cognitive Dysfunction
Modafinil to Prevent Postoperative Cognitive Decline
Postoperative cognitive dysfunction is a well-recognized complication of surgery. The aim of the study is to investigate whether cognitive dysfunction is reduced by the use of modafinil as shown by neurocognitive testing.The…
- Trial name
- NCT03914118
- Testing
- Preoperative modafinil + postoperative modafinil
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Postoperative Gastric Distension, Postoperative Gastrointestinal Dysfunction
Anti-Bloating Patch for Postoperative Gastric Distension After Cardiac Surgery
Postoperative gastric distension is a common gastrointestinal complication after cardiac surgery and may delay recovery, prolong intensive care unit (ICU) stay, and reduce patient comfort.
- Conditions
- Postoperative Gastric Distension, Postoperative Gastrointestinal Dysfunction, Cardiac Surgery
- Trial name
- ABP-CS (NCT07677423)
- Testing
- Anti-Bloating Patch, Standard Perioperative Care
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Southeast University, China
Postoperative Cognitive Dysfunction
Correlation Between Markers of Neuronal Injury and Cognitive Dysfunction After Coronary Artery Bypass Surgery
This study aims to evaluate the possible Correlation Between Serum Levels of Markers of Neuronal Injury and Cognitive Dysfunction after Coronary Artery Bypass Surgery.
- Trial name
- NCT01550159
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Maria José Carvalho Carmona
Postoperative; Dysfunction Following Cardiac Surgery
Is Six Weeks Too Long for First Outpatient Review After Cardiac Surgery?
Although the first outpatient review following cardiac surgery is conventionally scheduled for six weeks after hospital discharge, there is no evidence to support this practice.
- Trial name
- FORCAST6 (NCT02832427)
- Where
- United Kingdom
- Volunteers
- 85 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Other Functional Disturbances Following Cardiac Surgery
Pilates-based Cardiopulmonary Physical Therapy for In-Patients After Cardiac Surgery
The purpose of this clinical trial is to evaluate the effect of pilates-based cardiopulmonary physical therapy (CPT) for in-patients after cardiac surgery.
- Trial name
- PBCPT (NCT02437240)
- Testing
- Pilates-based CPT, Traditional CPT
- Volunteers
- 140 people
- Sponsor
- National Yang Ming Chiao Tung University
Atrial Fibrillation
Subclinical Postoperative Atrial Fibrillation
Postoperative atrial fibrillation and atrial flutter (POAF) is the most common complication after cardiac surgery requiring intervention or prolonged hospital stay.
- Trial name
- POAF-ILR (NCT02522364)
- Testing
- BioMonitor device, Standard
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Postoperative; Dysfunction Following Cardiac Surgery
Oral Triiodothyronine for Infants Less Than 5 Months & Malnourished Children Undergoing Cardiopulmonary Bypass in Indonesia
Infants and children undergoing cardiac surgery require mechanical support for circulation called cardiopulmonary bypass. The artificial pump ensures that blood flow to the body is maintained during surgical procedure on the…
- Trial name
- I-TRICC (NCT02222532)
- Testing
- Tetronine
- Where
- Indonesia
- Volunteers
- 224 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Postoperative; Dysfunction Following Cardiac Surgery
Impact of Mobilization on Cardiac Surgery
The objective of this study is to investigate the effects of a program of early mobilization in the functional capacity in patients undergoing coronary artery bypass grafting in short and long- term.
- Trial name
- NCT02312648
- Testing
- Interventional Group, Control group
- Volunteers
- 52 people
- Sponsor
- Luciana Chiavegato
Atrial Fibrillation, Inflammatory Marker
Red Cell Distribution Width as a Predictor for Post Operative Atrial Fibrillation After Open Heart Surgries
In this study we investigate the correlation between RDW and POAF, as we use the RDW as a predictor for inflammation for prediction of POAF
- Conditions
- Atrial Fibrillation, Inflammatory Marker, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT06286111
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Cognitive Dysfunction, Postoperative, Cognitive Dysfunction
Assessment of Brain Oxygen Drops During Surgery and Related Risk Factors for Cognitive Problems After Heart Surgery
This study examines whether decreases in brain oxygen levels during cardiac surgery are linked to postoperative cognitive dysfunction and identifies other factors that may increase the risk of cognitive impairment.
- Conditions
- Cognitive Dysfunction, Postoperative, Cognitive Dysfunction, Cardiac Surgery
- Trial name
- NCT07361068
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Functional Disturbances Following Cardiac Surgery
Neuroprotection With Erythromycin in Cardiac Surgery
Neurological complications occur in open heart surgery with a frequency of 40% and they range from major neurological deficits (due to a stroke) to neurocognitive and behavioral disorders.
- Trial name
- NCT01274754
- Where
- 2 sites in Greece
- Volunteers
- 40 people
- Sponsor
- AHEPA University Hospital
Postoperative Cognitive Dysfunction, Cerebrovascular Accident
Neurological Outcome After Minimal Invasive Coronary Artery Bypass Graft
Primary objectives: Assessment of the incidence of postoperative cognitive dysfunction (POCD), cerebrovascular accident (CVA), and delirium after minimal invasive coronary artery bypass grafting (Endo-CABG).
- Conditions
- Postoperative Cognitive Dysfunction, Cerebrovascular Accident, Delirium
- Trial name
- NOMICS (NCT02979782)
- Testing
- Endo-CABG, PCI
- Where
- 2 sites in Belgium
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Perioperative Bleeding, Coagulopathy During Cardiac Surgery
Flow-Based Platelet Function Assessment Using Total Thrombus-Formation Analysis System (T-TAS) and Early Bleeding After Cardiac Surgery With Cardiopulmonary Bypass (CPB)
The goal of this observational study is to learn how flow-based platelet function measured with the Total Thrombus-formation Analysis System (T-TAS) relates to early postoperative bleeding in adults undergoing cardiac surgery…
- Conditions
- Perioperative Bleeding, Coagulopathy During Cardiac Surgery, Platelet Dysfunction, Cardiac Surgery
- Trial name
- TTAS-CPB (NCT07619261)
- Testing
- Total Thrombus-formation Analysis System (T-TAS)
- Volunteers
- 30 people
- Sponsor
- Hospital de la Santa creu i Sant Pau - Barcelona
Postoperative Dysfunction Following Cardiac Surgery
Multiple Daily Doses of Aspirin to Overcome Hyporesponsiveness Post Cardiac Bypass Surgery (ASACABG)- Part B
Cardiac bypass surgery is an important treatment for patients with severely blocked arteries (tubes that delivery oxygen and nutrients to the heart).
- Trial name
- NCT01902498
- Testing
- Aspirin
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Hamilton Health Sciences Corporation
Heart; Dysfunction Postoperative, Cardiac Surgery
Oral Oxycodone After Major Cardiac Surgery
Postoperative pain and analgesic treatment still remains a challenge in daily perioperative medicine. Skin incisions, intraoperative tissue retraction and -dissection, intravasal cannulations and drainages, sternotomy and…
- Trial name
- NCT01816581
- Testing
- Targin, Oxynorm, Morphine
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Ventilator-Induced Diaphragm Dysfunction
Study of TransAeris® System for Enhanced Recovery After Surgery in France
This study will be conducted as a randomized trial of the TransAeris system for the prevention and treatment of ventilator-induced diaphragm dysfunction (VIDD) in patients identified prior to surgery to be at greater risk of…
- Trial name
- ERAS (NCT05404477)
- Testing
- TransAeris System
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Synapse Biomedical
Intracranial Embolism and Thrombosis, Postoperative Complications
TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique
The purpose of this study is to test the hypothesis that using three different techniques to anastomose coronary grafts to the aorta: partial occlusion, single cross clamp, or using the Heartstring anastomotic device, will change…
- Trial name
- NCT00294814
- Testing
- Proximal anastomosis using Heartstring anastomotic device
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Pain, Pain, Postoperative
Intervention Study to Enhance Patients' Pain Management After Cardiac Surgery
The main objective of this randomized controlled trial is to evaluate the effect of an intervention formed as a pain booklet provided to patients at discharge from hospital following cardiac surgery.
- Conditions
- Pain, Pain, Postoperative, Other Functional Disturbances Following Cardiac Surgery
- Trial name
- NCT01976403
- Testing
- Pain Booklet
- Where
- Norway
- Volunteers
- 416 people
- Sponsor
- Oslo Metropolitan University