Clinical trials: Postoperative Abdominal Adhesions
Ulcerative Colitis, Familial Polyposis
An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surgery
This will be a prospective, multi-center, randomized, single blind study to collect and evaluate post-market clinical data on the SprayShield Adhesion Barrier System as an adjuvant to good surgical technique for the reduction of…
- Trial name
- NCT01002287
- Testing
- SprayShield Adhesion Barrier System, Good Surgical Technique Alone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Integra LifeSciences Corporation
Chronic Pain, Tissue Adhesion
Laparoscopic Adhesiolysis for Chronic Abdominal Pain Revisited
Chronic abdominal and pelvic pain is a common complaint following peritoneal surgery, affecting 20-40% of patients. Adhesions account for 60% of chronic postoperative pain cases, suggesting that adhesiolysis can play an important…
- Trial name
- NCT02983916
- Testing
- Adhesiolysis
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Radboud University Medical Center
Abdominal Adhesions
Clinical Study of the Effectiveness, Tolerability and Safety of the Drug "Anti-spike, Gel, 100 g in Bottles in Package No. 1" Produced by the Republican Unitary Enterprise "Unitekhprom BSU", With a Single Intraperitoneal Use After Surgery in Adult Patients With Acute Phlegmonous Appendicitis
The purpose of the clinical trials is the evaluation of the effectiveness and safety of a single intraperitoneal use of the drug "Antispike, gel, 100 g in a bottle" produced by Unitary Enterprise Unitehprom BSU, Belarus in…
- Trial name
- OLTOSPAN-02 (NCT06365632)
- Testing
- Antispike gel, 100 g in a flask, produced by UNITEHPROM BSU, Republic of Belarus, antegrade appendectomy
- Where
- Belarus
- Volunteers
- 100 people
- Sponsor
- Research Institute for Physical Chemical Problems of the Belarusian State University
Tissue Adhesions
The Effect of Adhesiolysis During Elective Abdominal Surgery on Per- and Postoperative Complication, Quality of Life and Socioeconomic Costs
Official title: LAPAD - A prospective study on the effect of adhesiolysis during elective laparotomy or laparoscopy on per- and postoperative complication, quality of life and socioeconomic costs Background: With improved…
- Trial name
- LAPAD (NCT01236625)
- Testing
- Adhesiolysis
- Where
- Netherlands
- Volunteers
- 752 people
- Sponsor
- Radboud University Medical Center
Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions
Adhesion Prevention in ASBO Surgery Using 4DryField® PH
Post-surgical adhesions occur in up to 90% of abdominal surgeries, often leading to complications like adhesive small bowel obstruction (ASBO) and chronic pain.
- Conditions
- Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions, Bowel Obstruction, Abdominal Surgery Complications
- Trial name
- ADHERE (NCT07078981)
- Volunteers
- 189 people
- Sponsor
- Alessio Giordano
Ileus, Post-Operative Adhesions
A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection
The purpose of this study is to establish preliminary evidence of the efficacy, safety, and tolerability of LB1148 for the treatment of post-operative ileus and intra-abdominal adhesions in subjects undergoing elective bowel…
- Trial name
- PROFILE (NCT02836470)
- Testing
- LB1148
- Where
- 28 sites in United States
- Volunteers
- 112 people
- Sponsor
- Palisade Bio
Hernia of Abdominal Wall, Incisional Hernia
"BP as a New Device for Surgery and Solid Cancer and Hematopoietic System Tumors Treatment. Effects of BP Implantation"
Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias in humans, in laparotomic procedures and as a new device…
- Trial name
- DM159 (NCT02328352)
- Testing
- BP selfstanding felt, PP mesh, BP intraperitoneal mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Adhesions, Ileus
A Study to Evaluate the Safety, Tolerability and Efficacy of LB1148 for Subjects Undergoing Elective Bowel Resection
The purpose of this study is to assess the safety, tolerability, and preliminary efficacy of LB1148 in subjects undergoing elective bowel resection.
- Trial name
- NCT04100447
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Ronald Hurst, MD, FACS
Abdominal Adhesions
Evaluation of the Safety and Effectiveness of Sepraspray™ in Reducing Post-surgical Adhesions
This study will examine the safety and efficacy of Sepraspray in the following model of abdominal surgery: total proctocolectomy and pelvic pouch with diverting ileostomy via laparotomy to treat ulcerative colitis or familial…
- Trial name
- NCT00665730
- Testing
- Sepraspray
- Where
- 6 sites in Czechia, Denmark and 3 more
- Volunteers
- 5 people
- Sponsor
- Genzyme, a Sanofi Company
Peritoneal Surface Malignancy, Postoperative Adhesion
SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery
This dual-centre, randomized controlled trial evaluates the safety and efficacy of high-purity Type-I collagen-based biomaterial, as a peritoneal substitute following peritonectomy in patients undergoing cytoreductive surgery…
- Conditions
- Peritoneal Surface Malignancy, Postoperative Adhesion, Bowel Obstruction, Wound Complications
- Trial name
- NCT07241091
- Testing
- High-Purity Type-I Collagen Scaffold, Standard Peritonectomy Closure
- Where
- 2 sites in India
- Volunteers
- 60 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara