Clinical trials: Postoperative Acute Kidney Injury
Acute Kidney Injury, Cardiac Surgery
Pre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery
Cardiac surgery with cardiopulmonary bypass exposes patients to the risk of post-operative acute kidney injury. In the specific setting of cardiac surgery, acute kidney injury is often of multifactorial origindue to particular…
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Sodium/Glucose Cotransporter Inhibitor 2
- Trial name
- SGLT2i-PO-AKI (NCT06432751)
- Testing
- Post Operative Acute Kidney Injury
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Hospices Civils de Lyon
Acute Kidney Injury, Pneumonectomy
Prognostic Significance of Preoperative Nutritional Status on Postoperative Acute Kidney Injury
The incidence of postoperative acute kidney injury (AKI) is high in patients undergoing lung resection surgery, especially in the elderly.
- Trial name
- NCT06496802
- Testing
- no intervention
- Volunteers
- 1,880 people
- Sponsor
- Wanmin Liao
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Postoperative Acute Kidney Injury
Predictive Nomogram for Postoperative Acute Kidney Injury in Older Patients Undergoing Noncardiac Surgery
Postoperative acute kidney injury is associated increased risk of morbidity and mortality. Older patients are at high risk of developing postoperative acute kidney injury.
- Trial name
- NCT05507268
- Testing
- no intervention
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Chinese PLA General Hospital
Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE
NGAL Predictive Value of Acute Kidney Failure After Cardiac Surgery in Patients With Preoperative Chronic Kidney Failure
Primary endpoint: To evaluate predictive value of plasmatic levels of Neutrophil Gelatinase Associated Lipocalin (NGAL) to reveal acute kidney failure after cardiac surgery in patients with preoperative chronic kidney failure…
- Conditions
- Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE, Cardiac Surgical Procedures
- Trial name
- NGAL-CKF (NCT01227122)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Jean Minjoz
Acute Kidney Injury
Effects of BRS and LRS on Postoperative Acute Kidney Injury
1. Title: Effects of Sodium Bicarbonate Ringer's Injection and Sodium Lactated Ringer's Injection on postoperative acute kidney injury in patients undergoing major abdominal surgery: a randomized, controlled, open-label clinical…
- Trial name
- BRS/LRS (NCT04835038)
- Testing
- Sodium Bicarbonate Ringer's Injection, Sodium Lactated Ringer's Injection
- Where
- China
- Volunteers
- 3,400 people
- Sponsor
- Tongji Hospital
Arthroplasty, Replacement, Knee, Acute Kidney Injury
After Surgery Acute Renal Failure Incidence in Total Knee Arthroplasty With and Without Tourniquet
This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial
- Conditions
- Arthroplasty, Replacement, Knee, Acute Kidney Injury, Tourniquets, Knee Osteoarthritis
- Trial name
- NCT03795805
- Testing
- total knee arthroplasty, Tourniquet limb cuff, Intaarticular lidocain
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Surgery--Complications, Perioperative/Postoperative Complications
Telemedicine Notifications With Machine Learning for Postoperative Care
The ODIN-Report study will be a randomized controlled trial of the effect of providing machine learning risk forecasts to providers caring for patients immediately after surgery on serious complications.
- Conditions
- Surgery--Complications, Perioperative/Postoperative Complications, Acute Kidney Injury, Hospital Mortality
- Trial name
- ODIN-Report (NCT03974828)
- Testing
- Anesthesia Control Tower Notification
- Sponsor
- Washington University School of Medicine
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania
Acute Kidney Injury
Risk Factors Related to Postoperative Acute Kidney Injury in Elderly Patients Undergoing Joint Replacement
Total hip arthroplasty refers to the replacement of the femoral head and acetabulum damaged by disease or trauma with an artificial hip joint, thereby restoring joint activity and original function.
- Trial name
- NCT04132921
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Xuzhou Medical University
Femur Fracture, Acute Renal Failure
Preventive Norepinephrine Infusion During Surgery for Upper Femoral Fracture and Post-operative Acute Renal Failure
The fracture of the upper extremity of the femur (FESF) is one of the most common fractures in traumatology. In France, FESF affects more than 65,000 individuals per year and could involve up to 150,000 people per year by 2050…
- Trial name
- NORAKI (NCT05566132)
- Where
- France
- Volunteers
- 676 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Renal Insufficiency, Acute, Cardiac Surgery Associated - Acute Kidney Injury
Renal Resistive Index in Early Detection of Postoperative Acute Kidney Injury
The primary aim of our study was to investigate the role of renal doppler ultrasonography (USG) and preoperative/postoperative renal resistive index (RRI) in the early prediction of AKI.
- Trial name
- NCT06791304
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Acute Kidney Injury
Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery
This project aims to conduct an international, prospective, multicentre, observational study to determine the incidence of Postoperative Acute Kidney Injury (PO-AKI) in hospitalized children after noncardiac surgery.
- Trial name
- POAKIDS (NCT07351149)
- Where
- 16 sites in Australia, Brazil and 8 more
- Volunteers
- 2,000 people
- Sponsor
- Uppsala University
Postoperative Acute Kidney Injury, Arthroplasty
Risk Factors for Acute Kidney Injury in Patients Undergoing Arthroplasty
The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty.
- Trial name
- NCT06296108
- Testing
- acute kidney injury
- Where
- Turkey (Türkiye)
- Volunteers
- 911 people
- Sponsor
- Ankara University
Acute Kidney Injury, Surgery-Complications
Development of Synthetic Medical Data Generation Technology to Predict Postoperative Complications
<Development of synthetic medical data generation technology to predict postoperative complications> In order to develop a model for predicting the occurrence of complications after surgery, it is necessary to establish a cohort…
- Conditions
- Acute Kidney Injury, Surgery-Complications, Nephropathy
- Trial name
- NCT05986474
- Where
- South Korea
- Volunteers
- 410,000 people
- Sponsor
- Seoul National University Hospital
Hypotension
Decision Support for Intraoperative Low Blood Pressure
The purpose of this study is to determine whether a decision support system can improve the adherence to thresholds for low blood pressure by anesthesia providers, which in turn prevents their patients from having organ injury.
- Trial name
- NCT02726620
- Testing
- Attending real-time decision support, In-room real-time decision support, Attending feedback emails
- Where
- United States
- Volunteers
- 22,435 people
- Sponsor
- Vanderbilt University Medical Center
Acute Kidney Injury
Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI
Acute kidney injury (AKI) occurs in up to 30% of patients undergoing coronary artery bypass graft (CABG) surgery, and often requires patients to go on dialysis.
- Trial name
- NCT03810417
- Testing
- Digoxin Antibodies Fab Fragments, Baseline EO > 360 pM, EO < 360 pM
- Where
- 2 sites in United States
- Volunteers
- 267 people
- Sponsor
- University of Maryland, Baltimore
Acute Kidney Injury, Acute Kidney Disease
The Effect of Preoperative Biological Age on Hemodynamics and Renal Function
Background The aim of this study is to explore the potential value of preoperative biological age as a predictor of intraoperative hemodynamic changes and postoperative renal function injury.
- Conditions
- Acute Kidney Injury, Acute Kidney Disease, Intraoperative Hypotension, Post-induction Hypotension
- Trial name
- NCT07080086
- Volunteers
- 268,833 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Acute Kidney Injury, Liver Transplant; Complications
Effect of Terlipressin on the Incidence of Early Postoperative Acute Kidney Injury in Liver Transplantation Patients
The goal of this clinical trial is to evaluate the effect of intraoperative terlipressin on the incidence of early postoperative acute kidney injury in deceased doner liver transplantation.
- Trial name
- NCT06108362
- Testing
- Terlipressin, normal saline
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy
Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC
Acute renal injury (AKI) is a common complication after cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), and is associated with worse outcomes.
- Conditions
- Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy, Hydration, Diuresis
- Trial name
- NCT05939193
- Testing
- Urine-guided hydration, Routine hydration, Forced administration of furosemide
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Peking University First Hospital