Clinical trials: Postoperative Analgesia After Disc Surgery
Pain
The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen on Postoperative Pain After Spine Surgery
The analgesic effect of dexamethasone is not well described, but studies have shown that dexamethasone can be a safe part of a multimodal analgesic strategy after surgery.
- Trial name
- NCT01953978
- Testing
- Dexamethasone, Morphine, Zofran
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Analgesia After Disc Surgery
Evaluation of Thoracolumbar Interfascial Plane Block for Postoperative Analgesia After Herniated Lumbar Disc Surgery
Several regional anesthesia have been shown to improve postoperative outcomes in many studies. The transversus abdominis plane (TAP) block provides anesthesia to the abdominal wall by introducing local anesthetic to the anterior…
- Trial name
- NCT03285282
- Testing
- Thoracolumber interfascial plane block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Lumbar Disc Herniation
An mTLIP Block for Analgesia Management After Lumbar Spinal Surgery.
Pain management is an important issue following lumbar spinal surgery. Wound infiltration is a technique that a local anesthetic solution is infiltrated into the tissues around the surgical area.
- Trial name
- NCT03967314
- Testing
- TLIP block group (group T), Wound infiltration group (group W)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Acute Pain, Spinal Stenosis
Quadro-Iliac vs Thoracolumbar Interfascial Plane Block for Analgesia After Single-Level Lumbar Disc Surgery
The investigators aim to compare the postoperative analgesic efficacy of the classical thoracolumbar interfascial plane block and the Quadro-iliac plane block for postoperative analgesia management after lumbar disc surgery.
- Trial name
- NCT07348419
- Testing
- Quadro-iliac plane block, Classical thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Samsun University
Spondylolisthesis, Lumbar Disc Herniation
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia.
- Conditions
- Spondylolisthesis, Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Trial name
- RCT-ESPB (NCT05345249)
- Testing
- Ropivacaine Hydrochloride Injection, Sodium chloride
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- Ilse van de Wijgert
Patients Undergoing a Lumbar Slipped Disc Surgery
Co-analgesic Effects of Dexamethasone and Pregabalin After Lumbar Slipped Disc Surgery
The aim of the study is to show a decrease in postoperative pain during the first postoperative mobilization surgery lumbar disc herniation through a co-analgesia with a single dose of dexamethasone, pregabalin, or a combination…
- Trial name
- DEXA-PG-HD (NCT01811251)
- Testing
- Pregabaline (150mg), Dexamethasone (20mg/5ml; 0.2mg/kg)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intervertebral Disc Prolapse
Pregabalin Compared to Gabapentin for Pain Control in Lumbar Disc Surgery
Pregabalin is claimed to have superior analgesic effect at lower doses and better pharmacological profile as compared to gabapentin esp. in perioperative pain control after major surgeries like intervertebral disc surgery.
- Trial name
- NCT02120703
- Testing
- Pregabalin, Gabapentin
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Aga Khan University
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery
Introduction: Improving postoperative pain management after spinal surgery is a significant challenge for surgeons and anesthesiologists.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spine Instability
- Trial name
- NCT05871073
- Testing
- Ropivacaine 0.75% Injectable Solution, dexamethasone 8mg
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Hospital Fattouma Bourguiba
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
Lumbar Spine Instability, Lumbar Spinal Stenosis
Modified-Thoracolumbar Interfascial Plane Block and Erector Spinae Plane Block Following Lumbar Instrumentation Surgery
Ultrasound (US)-guided peripheral nerve blocks have been used increasily due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Conditions
- Lumbar Spine Instability, Lumbar Spinal Stenosis, Lumbar Disc Disease, Lumbar Spine Degeneration
- Trial name
- NCT04189341
- Testing
- Erector spinae plane block (Group E), Modified-thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Lumbar Disc Herniation
Erector Spinae Plane Block and Modified-Thoracolumbar Interfascial Plane Block Following Lumbar Spinal Surgery
Ultrasound (US)-guided peripheral nerve blocks have been used increasily due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Trial name
- NCT04073095
- Testing
- Erector spinae plane block (Group E), modified-thoracolumbar interfascial plane block (Group T)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Lumbar Disc Herniation
Quadratus Lumborum Block for Lumbar Spinal Surgery
Spine surgery in thoracolumbar region is one of the most common surgeries performed for the treatment of leg and back pain. Pain management is especially important for these patients since chronic pain often occurs after surgery.
- Trial name
- NCT04981301
- Testing
- Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Lumbar Disc Herniation
QLB vs mTLIP for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle with the goal of anesthetizing the thoracolumbar nerves.
- Trial name
- NCT05217121
- Testing
- Quadratus Lumborum Block, Modified-thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Posterior Lumbar Interbody Fusion (PLIF), Postoperative Analgesia After Disc Surgery
Comparing Long-Acting Local Pain Relief Methods in PLIF Surgery
This study is being done to compare three ways of using long-acting local pain medicine around the surgical wound during open lumbar fusion surgery.
- Trial name
- NCT07919275
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine, Standard Analgesic Cocktail, Modified Analgesic Cocktail
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Lumbar Spinal Stenisis or Lumbar Herniated Intervertebral Disc
The Analgesic Effect of Nefopam on the Fentanyl Based PCA (Patient-controlled Analgesia) After Lumbar Spinal Surgery
Posterior lumbar spinal surgical pain leads to a severe degree of pain, and, hence, various means of pain management are required.
- Trial name
- NCT01808014
- Testing
- nefopam
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Delirium, Pain, Postoperative
Erector Spinae Plane Block vs Local Infiltration Following Fusion Surgery
The proposed intervention will examine two alternative methods for postoperative pain control. Two treatment arms of this study will include subjects who receive an erector spinae block (ESP) after induction of anesthesia but…
- Conditions
- Postoperative Delirium, Pain, Postoperative, Degenerative Disc Disease
- Trial name
- NCT06199999
- Testing
- Erector Spinae Block, Local infiltration with local anesthetic
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Rashmi Mueller
Lumbar Disc Herniation
QLB vs ESPB for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle to anesthetize the thoracolumbar nerves.
- Trial name
- NCT06477198
- Testing
- QLB, ESPB, Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University