Clinical trials: Postoperative Atrial Fibrillation
Atrial Fibrillation
Intravenous Lidocaine and Postoperative Outcomes After Cardiac Surgery
This study is being done to determine if lidocaine, administered during surgery and for 24 hours after surgery can reduce inflammation, thereby reducing the risk of atrial fibrillation and 30 day mortality after surgery.
- Trial name
- NCT00840918
- Testing
- Lidocaine
- Where
- India
- Volunteers
- 123 people
- Sponsor
- The Cleveland Clinic
Atrial Fibrillation
Interest of a Hybrid Connected Watch for Cardiac Rhythm Monitoring in Post-operative Cardiac Surgery
The objective of this single-center pilot study is, with the help of a connected watch, to show the absence of recurrence or maintenance of sinus rhythm in patients with a Post Operative Atrial Fibrillation (POAF) and to help…
- Trial name
- MONHYCARD (NCT05664308)
- Testing
- Clinical follow-up (ECG), Ongoing monitoring
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Nantes University Hospital
Atrial Fibrillation, Lung Transplant; Complications
Intraoperative Amiodarone to Prevent Atrial Fibrillation in Lung Transplant Patients
This study will prospectively evaluate the use of an amiodarone releasing hydrogel applied to the pulmonary veins and atria at the time of lung transplantation.
- Trial name
- NCT03221764
- Testing
- Amiodarone with CoSeal, CO2 driver
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
Hemorrhage, Atrial Fibrillation, Postoperative
Prevention of Retained-Blood Outcomes With Active Clearance Technology
Postoperative bleeding is a common consequence after heart surgery which can significantly impact outcomes and costs . When bleeding occurs, reliable postoperative blood evacuation of the pleural, mediastinal and pericardial…
- Trial name
- NCT02145858
- Testing
- Blood drainage post cardiac surgery using PleuraFlow System
- Where
- 2 sites in United States
- Volunteers
- 891 people
- Sponsor
- ClearFlow, Inc.
AF - Atrial Fibrillation
Predictors of Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Prospective Cohort Study
There are a wide range of significant epidemiological, clinical, and operative predictors for the development of post-CABG AF including older age, female gender, large LA diameter, higher CHA2DS2-VASc score, valve replacement and…
- Trial name
- NCT04193813
- Testing
- Observational
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Ain Shams University
Postoperative Atrial Fibrillation
The Effect of Ligament of Marshall Excision During Minimally Invasive Cardiac Surgery-Coronary Artery Bypass Grafting (MICS-CABG) on the Prevention of Postoperative New-Onset Atrial Fibrillation: A Multicenter, Prospective, Randomized, Triple-Blinded Study
After heart bypass surgery, many patients develop a heart rhythm problem called postoperative atrial fibrillation, or POAF for short. This issue happens to 20%-40% of all bypass patients.
- Trial name
- NCT07755072
- Testing
- MICS-CABG combined with excision of the Ligament of Marshall
- Where
- China
- Volunteers
- 628 people
- Sponsor
- Peking University Third Hospital
Postoperative Atrial Fibrillation, Lung Surgery
Perioperative Statins to Prevent AFib After Lung Surgery
The goal of this clinical trial is to learn whether short-term treatment with atorvastatin can prevent new abnormal rapid heart rhythms after lung surgery in adults aged 60 years or older who are scheduled to have a lung segment…
- Trial name
- STAT-LUNG (NCT07727681)
- Testing
- Atorvastatin
- Where
- 2 sites in China
- Volunteers
- 540 people
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation, Stroke
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who…
- Conditions
- Atrial Fibrillation, Stroke, Bleeding
- Trial name
- PACES (NCT04045665)
- Testing
- Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
- Where
- 106 sites in United States, Brazil and 3 more
- Volunteers
- 3,200 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Atrial Fibrillation, Cardiac Surgery
Diagnosis of Postoperative Atrial Fibrillation by a Smartwatch
The incidence of postoperative atrial fibrillation (POAF) after on-pump cardiac surgery remains high, at around 30%. POAF increases the risk of cardiac decompensation, stroke, acute myocardial infarction, and death, resulting in…
- Trial name
- FAWATCH (NCT05573633)
- Testing
- ECG, scanwatch
- Where
- France
- Volunteers
- 324 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Atrial Fibrillation
Atorvastatin Using as a Possible Prophylaxis of Postoperative Atrial Fibrillation After Cardiac Surgery
The purpose of this study is to evaluate the effectiveness of atorvastatin therapy (both during preoperative and postoperative period), as prophylaxis against postoperative atrial fibrillation after cardiac surgery, in a valve…
- Trial name
- PROFACE (NCT01570530)
- Testing
- Cardiac surgery
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Fundación General Universidad de Valladolid
Atrial Fibrillation, Postoperative Atrial Fibrillation
SGB for Prevention of Postop A-Fib After Cardiac SurgeryTrial
This research study is being conducted to determine whether a stellate ganglion block, a small injection in the neck that temporarily reduces sympathetic nervous system activity, can help reduce the risk of developing…
- Trial name
- NCT07893275
- Testing
- Stellate Ganglion Block Injection with 10 mL 0.5% Bupivacaine, Stellate Ganglion Block Injection with 10 mL Normal Saline
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Atrial Fibrillation
Prophylaxis for Patients at Risk to Eliminate Post-operative Atrial Fibrillation
After surgery on the lungs or esophagus, 12-46% of patients experience an irregular heart rhythm called atrial fibrillation. Although usually transient, post-operative atrial fibrillation is associated with longer stay in…
- Trial name
- PREP-AF (NCT04392921)
- Testing
- Amiodarone
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Ottawa Hospital Research Institute
Coronary Artery Disease, Atrial Fibrillation
Postoperative Lactate and Atrial Fibrillation After CABG
Postoperative atrial fibrillation (POAF) is associated with increased mortality and morbidity in patients undergoing isolated coronary artery bypass grafting (CABG).
- Trial name
- NCT05448521
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Post-operative Atrial Fibrillation (POAF)
Anthocyanin-Rich Table Grape Powder for Prophylaxis of Post-Operative Atrial Fibrillation
Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery and leads to worse outcomes. POAF is thought to be caused by the inflammatory state following cardiac surgery.
- Trial name
- NCT05991700
- Testing
- Freeze-Dried California Table Grape
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Michigan
Atrial Fibrillation, Post-operative Atrial Fibrillation
Gene Therapy for Post-Operative Atrial Fibrillation
This clinical trial will have 2 components: a brief dose-ranging study and a randomized comparison of 2 doses of AdKCNH2-G628S with control cardiac surgery patients.
- Trial name
- AFGT01 (NCT05223725)
- Testing
- AdKCNH2-G628S
- Where
- United States
- Sponsor
- University of Massachusetts, Worcester
Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
Colchicine for the Prevention of Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Single-Center, Strategy-Stratified, Randomized, Double-Blind, Placebo-Controlled Trial
Post-operative atrial fibrillation after coronary artery bypass grafting (CABG)
- Trial name
- NCT07611019
- Testing
- Colchicine 0.5 MG oral tablet twice daily
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation
Post-operative Corticosteroid Treatment After Mitral Valve Surgery
The aim of the study is to intestigate whether three days intravenous corticosteroid management prevent atrial fibrillations in adults after mitral valve surgery.
- Trial name
- MitralPOCS (NCT03682393)
- Testing
- Hydrocortisone
- Where
- Finland
- Sponsor
- Kuopio University Hospital
Atrial Fibrillation, Cardiac Surgery
Prevention of Atrial Fibrillation by Low-dose Landiolol Administration After Cardiac Surgery
Postoperative atrial fibrillation (POAF) is a common complication that occurs in 30-50% of patients after cardiac surgery and increases morbidity and mortality and hospital length of stay.
- Trial name
- LANDIPROTEC (NCT04607122)
- Testing
- Landiolol, Saline
- Where
- 3 sites in France
- Volunteers
- 400 people
- Sponsor
- CMC Ambroise Paré
CABG, Visceral Adipose Tissue
Impact of Visceral Adiposity on Postoperative Atrial Fibrillation After CABG
Obesity has become a major public health problem in both developed and developing countries, with a continuous increase particularly since the 1980s.
- Conditions
- CABG, Visceral Adipose Tissue, Atrial Fibrillation (AF)
- Trial name
- NCT07467941
- Testing
- Postoperative AF Group, Non-AF Group
- Volunteers
- 300 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
New Onset Atrial Fibrillation, Complications; Cardiac, Postoperative
Nifekalant Versus Amiodarone in New-Onset Atrial Fibrillation After Cardiac Surgery
Postoperative atrial fibrillation is a major complication of cardiac surgery, which could lead to high morbidity and mortality, increase duration of hospital stay and increase the cost of treatment.
- Trial name
- NCT05169866
- Testing
- Nifekalant, Amiodarone
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Beijing Anzhen Hospital