Clinical trials: Postoperative Bronchospasm
Respiratory Failure, Respiratory Infection
Avoiding Neuromuscular Blockers to Reduce Complications
The goal of this study to evaluate whether eliminating the use of non-depolarizing neuromuscular blocking agents (NMBA) for maintenance of general anesthesia reduces postoperative pulmonary complications in higher risk patients.
- Conditions
- Respiratory Failure, Respiratory Infection, Aspiration Pneumonia, Pneumonitis
- Trial name
- NCT03962725
- Testing
- Neuromuscular Blocking Agents, Anesthetic Adjuncts
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications
Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications
The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure (ΔP), in…
- Conditions
- Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications, Postoperative Respiratory Failure, Postoperative Bronchospasm
- Trial name
- NCT07186933
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Surgical Procedures, Operative, Anaesthesia
POPULAR: POst-operative PULmonary Complications After Use of Muscle Relaxants in Europe
International multicenter observational study of a random-sample cohort of patients undergoing any in-hospital surgical procedure under general or regional anaesthesia during a continued 14-day period of recruitment.
- Trial name
- POPULAR (NCT01865513)
- Where
- 2 sites in Germany, Sweden
- Volunteers
- 22,000 people
- Sponsor
- European Society of Anaesthesiology
Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis)
Intraoperative Paravertebral Block and Postoperative Complications
This study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis), Pulmonary Infections, Respiratory Failure Without Hypercapnia
- Trial name
- IPVB and POCs (NCT07211529)
- Testing
- Paravertebral Block (PVB)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Complication of Surgical Procedure, Acute Respiratory Failure, Adult
Prospective Evaluation of a RIsk Score for Postoperative Pulmonary COmPlications in Europe
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric…
- Conditions
- Complication of Surgical Procedure, Acute Respiratory Failure, Adult, Postoperative Respiratory Complications, Pulmonary Failure
- Trial name
- PERISCOPE (NCT01346709)
- Where
- 63 sites in Albania, Belgium and 19 more
- Volunteers
- 5,450 people
- Sponsor
- European Society of Anaesthesiology
Respiratory Failure, Pneumothorax
Driving Pressure And EFL in Adult Cardiac Surgery
During general anesthesia, functional residual capacity (FRC) is reduced. If the FRC is lower than the minimum volume required to maintain the opening of the airways, there is a derecruitment of the lung parenchyma, leading to…
- Conditions
- Respiratory Failure, Pneumothorax, Atelectasis, Respiratory Infection
- Trial name
- NCT03064659
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Ospedale San Raffaele