Clinical trials: Postoperative Cataract
Cataract
Retained Lens Fragments After Phacoemulsification
The purpose of this study is to investigate postoperative events in patients noted to have retained nuclear fragments in the anterior vitreous during routine phacoemulsification and in those who did not.
- Trial name
- NCT02058394
- Testing
- Phacoemulsification
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Ophthalmic Consultants, Corneal and Refractive Surgery Associates, PC
Posterior Capsule Opacification, Postoperative Complications
Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract Surgery
This prospective, randomized, clinical trial looks to compare children undergoing congenital cataract surgery with intraocular lens (IOL) implantation in terms of visual axis obscuration as well as postoperative complications…
- Trial name
- NCT02491918
- Testing
- cataract surgery, Intraocular lens implantation
- Volunteers
- 61 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Postoperative Pain, Cataract
Midazolam Additive to Local Anesthetic in Peribulbar Block
Regional eye blocks are usually preferred for ophthalmic procedures. Peribulbar block (PBB) is a safe alternative for patients undergoing cataract surgery.
- Conditions
- Postoperative Pain, Cataract, Local Anaesthetic Complication, Midazolam
- Trial name
- NCT03397069
- Testing
- Peribulbar block (control), Peribulbar block(M1), Peribulbar block(M2)
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Corneal Endothelial Cell Loss, Pseudoexfoliation Syndrome
Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome
To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.
- Trial name
- NCT05447130
- Testing
- phacoemulsification
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Dry Eye
Role of Postoperative Lubrication in Cataract Surgery
Cataract and dry eye are two conditions occurring frequently in the elderly. Several reports suggested a deterioration of dry eye after cataract surgery, causing a significant impact on patients' postoperative satisfaction as…
- Trial name
- NCT06555224
- Testing
- Systane Hydration MDPF eye drops
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Endophthalmitis Following Cataract Surgery
Compare PPV With and Without Silicone Oil in Managing Postoperative Endophthalmitis
Comparing PPV with and without silicone oil in managing postoperative endophthalmitis
- Trial name
- Endopthalmitis (NCT06990607)
- Testing
- Pars plana Vitrectomy, Silicone Oil
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Cataract
Postoperative Total Wavefront Pattern Between Two Types of Intraocular Lenses Implanted in Cataract Surgery
With the advancement of cataract eye surgery and wavefront sensors, the previously unquantifiable refractive measurements have been identified and the high order aberrations have shown their effect on high resolution imaging.
- Trial name
- NCT04701255
- Testing
- phacoemulsification with intraocular lens implantation, ocular aberrometer assesment
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cataract Surgery, Shallow Anterior Chamber
FLACS vs Phaco in Shallow Anterior Chamber
Phacoemulsification in eyes with a shallow anterior chamber (ACD < 2.2mm) presents with problems of safe access to the cataract and increased vulnerability of the endothelium and a higher tendency of complications such as…
- Conditions
- Cataract Surgery, Shallow Anterior Chamber, Phacoemulsification
- Trial name
- NCT03587909
- Testing
- Phacoemulsification Cataract SUrgery, Femtosecond Cataract Surgery
- Where
- India
- Volunteers
- 91 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract Senile
Axial Length Variability
The accuracy of IOL calculation relies on the one hand on axial length measurements and on the other hand on corneal and lens thickness measurements.
- Trial name
- NCT04580550
- Testing
- Axial length variability
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract Senile
Evaluating App-Based Vision Testing (WHOeyes) Combined With the Questionnaire as a Substitute for One-Week Postoperative In-Clinic Follow-Up in Age-Related Cataract Patients: A Multi-center Randomized Controlled Trial
The goal of this clinical trial is to learn if an app-based vision testing (WHOeyes) combined with a questionnaire can recognize those who have to go back to the hospital, and thus replace the in-clinic 1-week review after an…
- Trial name
- NCT06429527
- Testing
- WHOeyes combined with a questionnaire.
- Where
- China
- Volunteers
- 334 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract, Lens Opacities
Premium Trifocal IOL Comparative Analysis
Short and long-term analysis of the refraction correction and optical image quality of modern premium intraocular lenses (IOLs) with the establishment of a database for quality assurance and optimization the computation constants…
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT04875455
- Testing
- POD F GF (BVI Medical), POD F (BVI Medical), Panoptix (Alcon Inc) IOL implantation
- Where
- 4 sites in Germany
- Volunteers
- 133 people
- Sponsor
- Beaver-Visitec International, Inc.
Inflammation Eye Pain, Postoperative Cataract
A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
This was a randomized, double-masked, vehicle-controlled, Phase 3 study evaluating the efficacy and safety of OCS-01 QD compared to vehicle in the treatment of inflammation and pain following cataract surgery.
- Trial name
- OPTIMIZE-1 (NCT05147233)
- Testing
- OCS-01, Vehicle
- Where
- 25 sites in United States
- Volunteers
- 241 people
- Sponsor
- Oculis
Microphthalmos With Congenital Cataracts
Long-term Postoperative Outcomes After Bilateral Congenital Cataract Surgery in Eyes With Microphthalmos
Cataract surgery in infantile eyes, which are microphthalmic, can be even more demanding. In addition, the frequent presence of other ocular and systemic anomalies such as nystagmus, glaucoma, amblyopia, and higher rate of…
- Trial name
- NCT01818037
- Testing
- Cataract surgery
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract, Retinitis Pigmentosa (RP)
Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients
This is a self-controlled randomized clinical trial to investigate the effect of capsular tension ring (CTR) implantation on intraocular lens (IOL) position in cataract patients with retinitis pigmentosa(RP).
- Trial name
- NCT07126470
- Testing
- CTR implantation
- Where
- 3 sites in China
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute
Cataract, Cataract Surgery
Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)
This study aims to generate data that characterizes visual outcomes, including the binocular distance-corrected intermediate visual acuity (DCIVA) at 66cm or defocus behavior, of the Clareon TruPlus modified monofocal intraocular…
- Conditions
- Cataract, Cataract Surgery, Cataract Bilateral, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- BMVDI (NCT07589894)
- Testing
- Clareon TruPlus IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colvard Kandavel Eye Center
Cataract, Glaucoma
To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.
The objective of this study is to evaluate ocular outflow dynamics of the eye using intraoperative tonographic biometry and assess its predictive value in improving postoperative outcomes.
- Trial name
- NCT07425496
- Testing
- disposable Deltran I pressure sensor
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The New York Eye & Ear Infirmary
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Evaluation of Visual Outcomes, Complications, and Neuroadaptation Following Bilateral Implantation of enVista Envy Trifocal Intraocular Lenses
The enVista Envy intraocular lens (IOL) manufactured by Bausch + Lomb is a new multifocal intraocular lens based on diffractive optics.
- Trial name
- NCT07696130
- Testing
- cataract surgery
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin
Introcular Lens Position
Axial Stability in Short and Long Eyes After Cataract Surgery
Post operative intraocular lens position is being measured after cataract surgery in 34 patients with long and short eyes.
- Trial name
- ACDC (NCT07210372)
- Where
- Austria
- Volunteers
- 34 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Postoperative Endophthalmitis
Intracameral Levofloxacin Versus Moxifloxacin After Cataract Surgery
This randomized study aims to compare the safety and efficacy of intracameral levofloxacin versus intracameral moxifloxacin administered at the end of phacoemulsification cataract surgery.
- Trial name
- NCT07850414
- Testing
- Levofloxacin, Moxifloxacin
- Volunteers
- 93 people
- Sponsor
- Assiut University