Clinical trials: Postoperative Disease Recurrence
Stage IA Non-small Cell Lung Cancer, Stage IB Non-small Cell Lung Cancer
Study to Evaluate NA-NOSE for Monitoring and Detecting Recurrence in Early Stage Lung Cancer
This clinical trial studies nanoscale artificial nose (NA-NOSE) in monitoring response and detecting recurrence after surgery or radiation therapy in patients with stage I or stage II non-small cell lung cancer (NSCLC).
- Conditions
- Stage IA Non-small Cell Lung Cancer, Stage IB Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lung Cancer
- Trial name
- NCT01840150
- Testing
- breath test, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Fox Chase Cancer Center
Non-small Cell Lung Cancer
A Single-arm Pilot Study of First-line Treatment With Carbognilumab Combined With Chemotherapy in Patients With STK11-mutated Advanced or Postoperative Recurrent Non-small Cell Lung Cancer
To evaluate the safety and tolerability of carbognilumab combined with chemotherapy as the first-line treatment for patients with STK11 mutated advanced or postoperative recurrent non-small cell lung cancer (NSCLC).
- Trial name
- NCT06331650
- Testing
- cadonilimab
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Lung Cancer, Non Small Cell Lung Cancer
Trial of ctDNA of Guidance to Determine PostOperative Radiation Therapy
Primary Objective: Evaluate the role of ctDNA positivity in decision making for postoperative therapy for non-small cell lung cancer.
- Conditions
- Lung Cancer, Non Small Cell Lung Cancer, Lung Cancer Recurrent
- Trial name
- PORT (NCT06979661)
- Testing
- Haystack™ ctDNA Assay
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
Rectal Cancer, Treatment
Safety and Efficacy Study of Cylindrical Abdominoperineal Resection to Treat Rectal Cancer
The purpose of this study is to determine whether cylindrical abdominoperineal resection is effective in the treatment of advanced very low rectal cancer
- Conditions
- Rectal Cancer, Treatment, Postoperative Complications, Neoplasm Recurrence, Local
- Trial name
- NCT00949273
- Testing
- cylindrical abdominoperineal resection
- Where
- 7 sites in China
- Volunteers
- 300 people
- Sponsor
- Beijing Chao Yang Hospital
Trigeminal Neuralgia, Microvascular Decompression
Impact of Teflon Technique on Recurrence After Microvascular Decompression for Trigeminal Neuralgia
The study aims to see if shredded Teflon placed away from the trigeminal nerve is equally effective in pain control in Trigeminal Neuralgia while minimizing the risks of pain recurrence due to granuloma formation when this…
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression, Teflon
- Trial name
- NCT07046247
- Testing
- Microvascular decompression for trigeminal neuralgia
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Valencia
Intraocular Melanoma, Melanoma (Skin)
Vaccine Therapy and Interleukin-12 With Either Alum or Sargramostim After Surgery in Treating Patients With Melanoma
RATIONALE: Vaccines made from peptides may make the body build an immune response. Combining vaccine therapy with interleukin-12 and either alum or sargramostim may kill more tumor cells.
- Trial name
- NCT00031733
- Testing
- MART-1 antigen, gp100 antigen, incomplete Freund's adjuvant
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Southern California
Rectum Cancer, Recurrent, Brachytherapy, Radioisotope
The Physical Dosimetry Study and Preliminary Clinical Results of 3D-printing Non Co-planar Template Assisted With CT-guidance for Iodine-125 Seed Brachytherapy in Pelvic Recurrent Rectum Carcinoma After Surgery and External Beam Radiotherapy
This study observes the efficacy and side effects of 3D-printing non co-planar template(3D-PNCT) assisted with CT-guidance for radioactive Iodine-125 seed(RIS) brachytherapy in pelvic recurrent rectum carcinoma retrospectively…
- Trial name
- NCT03890926
- Testing
- radioactive Iodine-125 seed implantation under the guidance of 3D template
- Volunteers
- 66 people
- Sponsor
- Peking University Third Hospital
Pneumothorax
Effect of Dissecting of The Inferior Pulmonary Ligament on Postoperative Pulmonary Reexpansion and Recurrence
This subject analysis of the influence of the dissociating inferior pulmonary ligament on pulmonary reexpansion and recurrence in the treatment of primary spontaneous pneumothorax by video assisted thoracic surgery.
- Trial name
- NCT02558608
- Testing
- DIPL, WR, thoracoscopic surgery
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Chinese Medical Association
Hepatocellular Carcinoma
A Phase III Study in Post-operative HBV-related Hepatocellular Carcinoma
Research Objective and Study End Points To evaluate the anti-HBV as well as HCC recurrence reducing effects of standard (18 months) lamivudine treatment at time of HBV reactivation with hepatitis flare up (HBV DNA > 105 copies/mL…
- Trial name
- NCT00455091
- Testing
- Adefovir Dipivoxil and Lamivudine
- Where
- 8 sites in Taiwan
- Volunteers
- 117 people
- Sponsor
- National Health Research Institutes, Taiwan
Incisional Hernia, Recurrent Hernia
Pulmonary Ventilation Function Between Patients With Primary and Recurrent Incisional Hernia: a Cross-sectional Study
Purpose Chronic obstructive pulmonary disease (COPD) is a risk factor for incisional hernia, COPD has persistent airflow restriction and pulmonary ventilation dysfunction.
- Conditions
- Incisional Hernia, Recurrent Hernia, COPD, Pulmonary Ventilation Function
- Trial name
- NCT05991024
- Testing
- the incisional hernia recurrent
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Fudan University
Postoperative Pain, Flare up
Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence
This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical…
- Conditions
- Postoperative Pain, Flare up, Flare Up, Symptom
- Trial name
- NCT07084194
- Testing
- Chitosan Nanoparticles Irrigant, aloe vera nanoparticles irrigant, Diode Laser Activation
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Minia University
Hepatocellular Carcinoma, Lenvatinib
Study of TACE Combined With Lenvatinib to Prevent Postoperative Recurrence in Patients With MVI Positive HCC
single-center clinical trial studies have verified the safety and effectiveness of transcatheter arterial chemoembolization (TACE) combined with lenvatinib in preventing postoperative recurrence of microvascular invasion (MVI)…
- Trial name
- NCT04911959
- Testing
- Lenvatinib, TACE
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Rectal Carcinoma
Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer
The purpose of this study is to evaluate the safety and oncological feasibility of robot-assisted surgery for mid/low rectal carcinoma compared with laparoscopic surgery.
- Trial name
- REAL (NCT02817126)
- Testing
- Robot-assisted resection, Laparoscopic resection
- Where
- 11 sites in China
- Volunteers
- 1,240 people
- Sponsor
- Fudan University
Crohn's Disease (CD)
Unraveling the Blood Microbiome in Postoperative Recurrence of Crohn's Disease
Crohn's disease, a chronic inflammation of the gastro-intestinal tract, is a disease with a complex pathogenetic background. Hereditary factors, environmental factors and the gut flora play a varying role in its onset, however…
- Trial name
- IBDbloom (NCT06770140)
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Survival, Postoperative Morbidity
Abdominal or Transanal TME for Rectal Cancer Therapy
This study assessed whether transanal TME in patients with rectal cancer is superior to open, laparoscopic, and robotic TME (abdominal TME (abTME)) regarding oncological outcome, postoperative morbidity and 90-day mortality.
- Conditions
- Survival, Postoperative Morbidity, Mortality, Recurrence
- Trial name
- NCT04969107
- Testing
- taTME, abdTME
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Cantonal Hospital of St. Gallen
Periapical Diseases, Periapical Periodontitis
Postoperative Pain After Conservative Root Canal Preparation
The goal of this clinical trial is to compare the pain experienced by healthy participants after root canal treatment with small versus large root canal sizes. The main questions it aims to answer are: 1.
- Conditions
- Periapical Diseases, Periapical Periodontitis, Postoperative Pain, Pulp Necroses
- Trial name
- NCT06545773
- Testing
- Root Canal Treatment with ProTaper Next Nickel-Titanium File (PTN), Root Canal Treatment withTruNatomy Nickel-Titanium File (TN)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Chronic Subdural Hematoma
Endovascular Embolization of Chronic Subdural Hematomas After Surgery
Chronic subdural hematomas (CSH) are one of the most frequent pathologies in emergency neurosurgical practice. Standard therapy for symptomatic CSH is surgical drainage.
- Trial name
- ENCLOSURE (NCT05220826)
- Testing
- Post surgical embolization of middle meningeal artery with liquid embolic agents (ethylene vinyl alcohol copolymers as Onix, Squid, Phil or Libro)
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Colorectal Cancer, Polyps
The Correlation of Postoperative Polyp Recurrence and Colorectal Cancer
Postoperative endoscopic polyp recurrence correlation of colorectal cancer: a retrospective cohort open-label study
- Trial name
- NCT07708415
- Testing
- Endoscopic polypectomy
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Gansu Provincial Hospital
Chronic Subdural Hematoma, Recurrence
The Effectiveness and Safety of Body Posture in Preventing Postoperative Recurrence for Chronic Subdural Hematoma
This study aims to investigate the effectiveness and safety of body posture to improve intracranial pressure in preventing postoperative recurrence for chronic subdural hematoma
- Trial name
- NCT06401772
- Testing
- Intracranial Hypotension Targeted(IHT) Body Posture
- Where
- China
- Volunteers
- 830 people
- Sponsor
- Huashan Hospital
Yiwu Cold Knife Technique for Multiple Endometrial Polyps
Yiwu Cold Knife Technique Versus Electrocision for Multiple Endometrial Polyps
# Clinical Trial Summary Template (Based on your endometrial polyp study) The goal of this clinical trial is to learn if cold knife hysteroscopic polypectomy (Yiwu procedure) works to treat multiple endometrial polyps in women.
- Trial name
- NCT07737301
- Testing
- Cold knife hysteroscopic polypectomy (Yiwu procedure), Electroresection hysteroscopic polypectomy
- Volunteers
- 850 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine