Clinical trials: Postoperative Hypoxemia
Pulmonary Atelectasis, Postoperative Complications
poStoperative Anesthesia Care: Facial Mask vs Hfnc and Thoracic Ultrasound for Reduction of Atelectasis Incidence
The primary aim of this study is to assess the efficacy of post-operatory HFNC in reducing the incidence of hypoxemia after gynecological oncology surgery, compared to the standard application of O2 through a Venturi mask; The…
- Conditions
- Pulmonary Atelectasis, Postoperative Complications, Gynecologic Cancer, Anesthesia
- Trial name
- SAMURAI (NCT04566419)
- Testing
- HFNC - Airvo 2, Oxygen
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Surgery, Trauma to the Abdomen
Non Invasive Ventilation in Abdominal Postoperative Period
Acute respiratory failure may occur early in the postoperative course, requiring endotracheal intubation and mechanical ventilation in selected patients, thus increasing morbidity and mortality and prolonging intensive care unit…
- Conditions
- Surgery, Trauma to the Abdomen, Acute Respiratory Failure
- Trial name
- NIVAS (NCT01971892)
- Testing
- Non Invasive ventilation (facial mask and NIV ventilator), Standard oxygen therapy with facial mask
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Postoperative Atelectasis, Postoperative Hypoxemia
REMINDers for Incentive Spirometry in PACU (REMIND-IS in PACU)
The purpose of this study is to determine if the frequency of use of incentive spirometry during the stay in the Post-Anesthesia Care Unit (PACU) increases with visual and auditory electronic reminders, as compared to not having…
- Conditions
- Postoperative Atelectasis, Postoperative Hypoxemia, Postoperative Pneumonia, Postoperative Pulmonary Complications
- Trial name
- NCT06304493
- Testing
- Alarms
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- University of Colorado, Denver
Postoperative Hypoxemia, Position Differences
Effect of Postural Changes on Postoperative Hypoxemia
The goal of this clinical trial is to learn which positioning strategy works better to prevent postoperative hypoxemia in surgical patients: semirecumbent positioning or lateral positioning.
- Trial name
- NCT07161817
- Testing
- Lateral positioning, Semirecumbent positioning
- Volunteers
- 1,200 people
- Sponsor
- Yuhu Ma
Hypoxemia, Ventilator Lung
Driving Pressure-guided Lung Protective Ventilation
The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving…
- Trial name
- DPV (NCT06361420)
- Testing
- Driving pressure-guided positive end expiratory pressure, Optimal oxygenation-guided positive end expiratory pressure, Ventilation strategy
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Yong Lin, PhD
Cardiac Surgery, Delirium - Postoperative
Effect of Hyperoxia or Hypoxemia on the Incidence of Delirium in Patients After Cardiac Surgery
Our goal was to study the effect of hyperoxia or hypoxemia on the incidence of delirium in patients after cardiac surgery.
- Conditions
- Cardiac Surgery, Delirium - Postoperative, Hyperoxia, Hypoxemia
- Trial name
- NCT07548905
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Southeast University, China
Elderly Patients, Laparoscopic Surgery
Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery
This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia…
- Conditions
- Elderly Patients, Laparoscopic Surgery, Postoperative Hypoxemia, Capnography
- Trial name
- NCT07652385
- Testing
- EtCO₂ Monitoring, Routine Monitoring
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Postoperative Respiratory Complication
The Effect of Continuous Pulse Oximetry Monitoring and Early Intervention Using Wearable Device on the Incidence of Postoperative Hypoxemia
Vital signs of postoperative patient are monitored intensively in post-anesthesia care unit or intensive care unit, but the frequency of surveillance decreases in typical surgical wards.
- Trial name
- NCT04694599
- Testing
- Low flow oxygen
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Lung Diseases
Comparison of Two Strategies of One-lung Ventilation in Patients Undergoing Carcinological Lung Resection Surgery.
During thoracic surgery, one-lung ventilation (OLV) is associated with hypoxemia, lung injury, and perioperative respiratory complications.
- Trial name
- I-PEEP-THO (NCT05525312)
- Testing
- "Open-lung" protective ventilation strategy, "Standard" protective ventilation strategy
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Hypoxemia
CPAP in Liver Transplant
The purpose of this study is to determine the effectiveness of continuous positive airway pressure compared to standard treatment in preventing the need for intubation and mechanical ventilation in patients who develop acute…
- Trial name
- NCT00510770
- Testing
- CPAP application
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Turin, Italy
Anesthesia, Atelectasis
Comparison of Two FiO2 (1 or 0.5) for Tracheal Extubation in Post-anesthesia Care Unit
The purpose of the study is to assess the optimal fraction of inspired oxygen (0.5 or 1) for extubation or removal of a supraglottic airway device after general anesthesia.
- Conditions
- Anesthesia, Atelectasis, Postoperative Complications, Hypoxemia
- Trial name
- EXTUBO2 (NCT04879290)
- Testing
- FiO2 0.5, FiO2 1
- Where
- France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Caen
Laparoscopic Bariatric Surgeries, Hypoxemia
Intra-Operative Modified Ventilator Mechanical Power in Laparoscopic Bariatric Surgeries
To compare the effects of two levels of mechanical power on the incidence of post-operative hypoxemia in morbid obese patients undergoing laparoscopic bariatric surgeries.
- Conditions
- Laparoscopic Bariatric Surgeries, Hypoxemia, Obese Patients
- Trial name
- NCT07065370
- Testing
- Group I ( volume-controlled ventilation with tidal volume 6-8ml/kg (predicted body weight) with respiratory rate 12-14 cycle/minute., Group II: (volume-controlled ventilation with tidal volume 6-8ml/kg )
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Hypoxemia, Postoperative Complications
Sigh Ventilation on Postoperative Hypoxemia in Cardiac Surgery
Postoperative pulmonary complications (PPCs) remain a frequent event after pump-on cardiac surgery and are mostly characterized by postoperative hypoxemia.These complications are significant contributors to prolonged intensive…
- Conditions
- Hypoxemia, Postoperative Complications, Cardiac Disease, Acute Lung Injury
- Trial name
- NCT06248320
- Testing
- Sigh ventilation
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Zhongda Hospital
Atelectasis, Postoperative Pulmonary, Bariatric Surgery
Postoperative Hypoxemia in Obese Patients
Postoperative atelectasis can cause postoperative hypoxia which might be avoided by applying pressure support during extubation of obese patients undergoing bariatric surgeries.
- Trial name
- RCT (NCT06589011)
- Testing
- Pressure Support Ventilation, spontaneously assisted breathing
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Theodor Bilharz Research Institute
Hypoxia, Post Pulmonary Resection
The Effect of Nasal Cannulae During the First 2 Hours Postoperative in Patient Undergoing Thoracotomy
At our institute,during the first 2 hour postoperative, we used to give supplement oxygen via face mask in patient having lung resection surgery.
- Trial name
- NCT01700088
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Mahidol University
Esophageal Carcinoma, Esophageal Adenocarcinoma
Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy
This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)<80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy.
- Conditions
- Esophageal Carcinoma, Esophageal Adenocarcinoma, Esophagectomy, PaO2
- Trial name
- NCT07309991
- Where
- 6 sites in China
- Volunteers
- 2,500 people
- Sponsor
- Sun Yat-sen University
Hypoxemia, Postoperative Complications
Heated Humidified Oxygen in PACU Patients
This study aims to determine whether heated and humidified oxygen therapy, compared with conventional room-temperature oxygen therapy, reduces the incidence of early hypoxemia in adult patients recovering from general anesthesia…
- Conditions
- Hypoxemia, Postoperative Complications, Anesthesia Recovery Period
- Trial name
- NCT07778420
- Testing
- Heated and Humidified Oxygen Therapy, Room-Temperature Oxygen Therapy
- Where
- 8 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Postoperative Residual Curarisation, Postoperative Hypoxemia
Postoperative Residual Curarisation at Arrival in the Post-anesthesia Care Unit
Several studies have documented that neuromuscular block often persists in the postanesthesia care unit (PACU). Residual paralysis is associated with postoperative complications such as hypoxia, weakness, and respiratory failure.
- Conditions
- Postoperative Residual Curarisation, Postoperative Hypoxemia, Postoperative Airway Obstruction
- Trial name
- NCT01362647
- Testing
- neuromuscular transmission monitoring, Pulse oximetry measurement
- Where
- Belgium
- Volunteers
- 625 people
- Sponsor
- Onze Lieve Vrouw Hospital
Hypoxemia, Hypercapnia
Optimising Ventilatory Strategies by Using Positive Respiratory Integer Measurements
Background Intermittent Positive Pressure Ventilation is used during general anesthesia but can lead to serious complications. Respiratory parameter settings can be adjusted to minimize the detrimental effects of this…
- Conditions
- Hypoxemia, Hypercapnia, Ventilator Associated Pneumonia, Complication of Anesthesia
- Trial name
- OPTIMVSPRIME (NCT06298435)
- Testing
- Intermittent Positive pressure ventilation
- Where
- Netherlands
- Volunteers
- 20,000 people
- Sponsor
- University Medical Center Groningen
Pulmonary Resection Surgery, One Lung Ventillation (OLV)
BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic Surgery
One-lung ventilation (OLV) is required during many thoracic surgical procedures and is associated with reduced functional residual capacity, atelectasis, ventilation-perfusion mismatch, hypoxemia, and potentially…
- Conditions
- Pulmonary Resection Surgery, One Lung Ventillation (OLV), General Anesthetic
- Trial name
- SIMPLE-PEEP (NCT07851740)
- Testing
- Fixed PEEP, BMI-adjusted PEEP
- Where
- 4 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Jesús Manuel Nieves Alonso