Clinical trials: Postoperative Hypoxemia
Acute Respiratory Distress Syndrome (ARDS), Pneumonia
Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.
Pre-market clinical trial on 81 aldults participants to evidence safety and performance of the non-CE-marked medical device INBENTUS VERSATILE ventilator.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Pneumonia, COPD (Chronic Obstructive Pulmonary Disease), Postoperative Respiratory Distress
- Trial name
- NCT07432191
- Testing
- INBENTUS VERSATILE
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Iconic Solutions By Murcia SL
Postoperative Hypoxemia
Preoperative ROX Index for Predicting Early Postoperative Hypoxemia in ENT Surgery
Early postoperative hypoxemia is a frequent complication after elective ear, nose, and throat (ENT) surgery and may adversely affect recovery in the post-anesthesia care unit (PACU).
- Trial name
- NCT07344103
- Testing
- rox ındex
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istinye University
Postoperative Hypoxemia
Optiflow® to Prevent Post-Extubation Hypoxemia afteR Abdominal Surgery (the OPERA Trial)
To evaluate whether early application of nasal high flow oxygen therapy after extubation can reduce the incidence of postoperative hypoxemia (defined as a PaO2/FiO2 ratio <300) after abdominal surgery in patients with…
- Trial name
- OPERA (NCT01887015)
- Testing
- Nasal high flow cannula (OptiflowTM, MR850 heated humidified, Fisher & Paykel Healthcare, Auckland, New Zealand)
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Clermont-Ferrand
Aortic Dissection
Angiotensin II Pathway and Postoperative Hypoxemia
Acute type A aortic dissection is often accompanied by postoperative hypoxemia, the cause of which is not fully understood. Angiotensin II is an important component of the renin-angiotensin system (RAS), which has been suggested…
- Trial name
- NCT05055570
- Testing
- No intervention
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Beijing Anzhen Hospital
Hypoxemia
Reminder-enhanced Incentive Spirometry Evaluation
The purpose of this study is to test whether automatic reminders with a light and a soft sound help patients improve deep breathing exercises after surgery.
- Trial name
- RISE (NCT07728214)
- Testing
- Alarms ON
- Volunteers
- 88 people
- Sponsor
- University of Colorado, Denver
Heart; Dysfunction Postoperative, Cardiac Surgery
Non-invasive Mechanical Ventilation After Cardiac Surgery
Non-invasive mechanical ventilation (NIV) has been used in hypoxic post-operative cardiac patients but more studies are necessary to clarify its respiratory and hemodynamic effects.
- Trial name
- NCT01457898
- Testing
- VPAP II®
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Irmandade Santa Casa de Misericórdia de Porto Alegre
Perioperative Diaphragmatic Excursion
Diaphragmatic Excursion Changes and Postoperative Oxygenation After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy and the associated pneumoperitoneum can impair diaphragmatic mechanics and reduce postoperative oxygenation.
- Trial name
- NCT07332728
- Testing
- Standard perioperative care with observational diaphragm ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istinye University
Pulmonary Disease, Postoperative Respiratory Complications
Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography
The purpose of this study is to determine whether Electrical Impedance Tomography can be used as sensitive and specific predictor in the detection of postoperative pulmonary complications (e.g.
- Conditions
- Pulmonary Disease, Postoperative Respiratory Complications, Malignant Neoplasm of Stomach, Liver Diseases
- Trial name
- NCT02337673
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Johannes Gutenberg University Mainz
Postoperative Complications, Respiratory Insufficiency
Optimal PEEP for Postoperative Oxygenation and Lung Aeration (ULTRASVENT-2)
The purpose of this multicenter, randomized controlled trial (ULTRASVENT-2) is to evaluate the effect of different positive end-expiratory pressure (PEEP) levels on postoperative oxygenation and lung aeration in adult patients…
- Conditions
- Postoperative Complications, Respiratory Insufficiency, Pulmonary Atelectasis, Positive-End Expiratory Pressure
- Trial name
- ULTRASVENT-2 (NCT07613177)
- Testing
- Intraoperative Positive End-Expiratory Pressure (PEEP) Regulation
- Where
- Russia
- Volunteers
- 360 people
- Sponsor
- Moscow Multidisciplinary Clinical Center "Kommunarka"
Pain, Postoperative, Obesity
TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean Analgesia
Cesarean deliveries are the most commonly performed surgery in the United States and account for 32.9% of all births.8,9 The ASA recommends the use of neuraxial opioids of post-cesarean analgesia partly because respiratory…
- Conditions
- Pain, Postoperative, Obesity, Respiratory Insufficiency
- Trial name
- NCT03282669
- Testing
- Intrathecal Morphine, Intravenous hydromorphone
- Sponsor
- Northwestern University
Morbid Obesity
Effects of Preoperative Respiratory Physical Therapy on Postoperative Respiratory Function After Bariatric Surgery
Background. Morbidly obese patients show an increased risk of hypoxemia and a higher incidence of postoperative pulmonary complications during the postoperative period resulting in prolonged hospital length of stay when compared…
- Trial name
- NCT01828632
- Testing
- Respiratory Physical Therapy
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Cerebral Hypoxia, Postoperative Delirium
Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery
The aim of this study is to distinguish possible differences in frequency of delirium after Volatile Induction and Maintenance of Anesthesia and Total Intravenous Anesthesia in case of undeliberate cerebral desaturation during…
- Trial name
- NCT02133638
- Testing
- Sevoflurane, Propofol
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- Negovsky Reanimatology Research Institute
Intraoperative Hypertension, Pain Threshold
Post SARS-Cov-2 Disease Anesthesia Events
Estimating and recording the rate of occurrence of pulmonary and cardiovascular complications during the perioperative period in patients with past covid infection
- Conditions
- Intraoperative Hypertension, Pain Threshold, Postoperative Pain, Postoperative Hypoxemia
- Trial name
- NCT05252234
- Testing
- Observation of hemodynamic status and post operative pain
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Postoperative Pulmonary Complications (PPCs), Hypoxemia
Lung Ultrasound Score and Postoperative Pulmonary Complications in Major Non-Thoracic Surgery
This prospective observational cohort study aims to evaluate the predictive value of perioperative lung ultrasound (LUS) score in determining early postoperative oxygen requirement and pulmonary complications in patients…
- Trial name
- LUS-POSTOP (NCT07515001)
- Volunteers
- 97 people
- Sponsor
- Dicle University
Bariatric Surgery
Does Pulmonary Compliance Optimization Through PEEP Manipulations Reduces the Incidence of Postoperative Hypoxaemia in Bariatric Surgery?
General anesthesia, even in patients in good health, impairs gas exchanges and ventilatory mechanics. These effects result primarily from atelectasis formation.
- Trial name
- NCT02579798
- Testing
- PEEP (positive end-expiratory pressure)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Brugmann University Hospital
Acute Aortic Dissection
A Pilot Study of Sivelestat Sodium to Shorten Mechanical Ventilation in Acute Aortic Dissection
This is A prospective, randomized, placebo-controlled, reestimable adaptive clinical study to evaluate the efficacy and safety of perioperative application of sivelestat sodium to shorten the duration of postoperative invasive…
- Trial name
- NCT05874700
- Testing
- Sivelestat sodium was given intravenously
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xiaotong Hou
Hypoxemia
Transcutaneous Auricular Vagus Nerve Stimulation for Reducing Postoperative Hypoxemia
Hypoxemia is a common complication in the post-anesthesia care unit (PACU) and represents one of the most meaningful factors associated with poor patient prognosis. Obese patients have a relatively higher incidence of hypoxemia.
- Trial name
- NCT07827131
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulator
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Hypoxemia, ARDS
Soluble VE-cadherin in Prediction and Diagnosis of Early Postoperative Hypoxemia After Cardiopulmonary Bypass
More than 2 million patients worldwide receive heart surgery every year, majority of these surgical patients will undergo cardiopulmonary bypass.
- Conditions
- Hypoxemia, ARDS, Lung Injury, Acute, Cardiopulmonary Bypass
- Trial name
- NCT05647382
- Testing
- blood cell analysis, blood gas surveillance, chest radiograph and echocardiography
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhuan Zhang
Hypoxemia, Acute Respiratory Failure
SuperNO2VA™ and General Anesthesia Postoperative Care
The purpose of the study is to randomly and prospectively evaluate the differences in outcomes between the control group (closed full facemask immediate post-extubation with standard oxygenating device used post-operatively in…
- Trial name
- NCT03969615
- Testing
- SuperNO2VA nasal positive airway pressure devic, Supplemental oxygen
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Vyaire Medical
Hypoxemia, Recruitment
Comparison of Four Different Recruitment Maneuvers in Patients After Coronary Surgery
The risk of respiratory failure after cardiac surgery is high, and it may result in many complications. The maneuver of alveolar recruitment may improve the oxygen transport in the human organism.
- Trial name
- RECR-CABG (NCT01457651)
- Testing
- Alveolar recruitment
- Where
- Russia
- Volunteers
- 76 people
- Sponsor
- Northern State Medical University