Clinical trials: Postoperative Hypoxia, active
Hypoxemia, Postoperative Complications
Heated Humidified Oxygen in PACU Patients
This study aims to determine whether heated and humidified oxygen therapy, compared with conventional room-temperature oxygen therapy, reduces the incidence of early hypoxemia in adult patients recovering from general anesthesia…
- Conditions
- Hypoxemia, Postoperative Complications, Anesthesia Recovery Period
- Trial name
- NCT07778420
- Testing
- Heated and Humidified Oxygen Therapy, Room-Temperature Oxygen Therapy
- Where
- 8 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Acute Respiratory Distress Syndrome (ARDS), Pneumonia
Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.
Pre-market clinical trial on 81 aldults participants to evidence safety and performance of the non-CE-marked medical device INBENTUS VERSATILE ventilator.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Pneumonia, COPD (Chronic Obstructive Pulmonary Disease), Postoperative Respiratory Distress
- Trial name
- NCT07432191
- Testing
- INBENTUS VERSATILE
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Iconic Solutions By Murcia SL
Postoperative Hypoxemia, Position Differences
Effect of Postural Changes on Postoperative Hypoxemia
The goal of this clinical trial is to learn which positioning strategy works better to prevent postoperative hypoxemia in surgical patients: semirecumbent positioning or lateral positioning.
- Trial name
- NCT07161817
- Testing
- Lateral positioning, Semirecumbent positioning
- Volunteers
- 1,200 people
- Sponsor
- Yuhu Ma
Hypoventilation, Hypoxemia
Postoperative Respiratory and Activity Monitoring
This study plans to learn more about specific breathing and activity recommendations for patients after surgery. Participants will be monitored after abdominal surgery to identify what activities help them breathe better and…
- Conditions
- Hypoventilation, Hypoxemia, Postoperative Pulmonary Complications
- Trial name
- NCT06239831
- Testing
- ExSpiron and ActivPAL Monitors
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Postoperative Complications, Respiratory Insufficiency
Optimal PEEP for Postoperative Oxygenation and Lung Aeration (ULTRASVENT-2)
The purpose of this multicenter, randomized controlled trial (ULTRASVENT-2) is to evaluate the effect of different positive end-expiratory pressure (PEEP) levels on postoperative oxygenation and lung aeration in adult patients…
- Conditions
- Postoperative Complications, Respiratory Insufficiency, Pulmonary Atelectasis, Positive-End Expiratory Pressure
- Trial name
- ULTRASVENT-2 (NCT07613177)
- Testing
- Intraoperative Positive End-Expiratory Pressure (PEEP) Regulation
- Where
- Russia
- Volunteers
- 360 people
- Sponsor
- Moscow Multidisciplinary Clinical Center "Kommunarka"
Hypoxemia
Transcutaneous Auricular Vagus Nerve Stimulation for Reducing Postoperative Hypoxemia
Hypoxemia is a common complication in the post-anesthesia care unit (PACU) and represents one of the most meaningful factors associated with poor patient prognosis. Obese patients have a relatively higher incidence of hypoxemia.
- Trial name
- NCT07827131
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulator
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Pulmonary Complications, Hypoxemia During Surgery
Association of Different Tidal Volumes and Postoperative Pulmonary Complications
The incidence of lung cancer in China is increasing year by year. Currently, the treatment primarily based on video-assisted thoracoscopic surgery (VATS) is still considered the optimal approach for early-stage non-small cell…
- Conditions
- Pulmonary Complications, Hypoxemia During Surgery, Thoracic Surgery, Video Assisted, One Lung Ventillation (OLV)
- Trial name
- NCT07372378
- Volunteers
- 650 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Hypoxia, Airway Obstruction, Postoperative
Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia
The goal of this study is to determine whether omitting tracheal suctioning immediately prior to extubation is non-inferior to routine tracheal suctioning with respect to early postoperative oxygenation among adult surgical…
- Conditions
- Hypoxia, Airway Obstruction, Postoperative, Sore Throat, Cough, Postoperative
- Trial name
- NCT07287293
- Testing
- Routine Endotracheal Suctioning, Omission of Endotracheal Suctioning
- Where
- Thailand
- Volunteers
- 408 people
- Sponsor
- Mahidol University
Atelectasis, Postoperative, Hypoxia
Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in ICU Patients
Atelectasis, hypoxemia, and ineffective sputum clearance are common problems in ICU patients. Continuous High-Frequency Oscillation (CHFO) is often considered to have a protective effect on the lungs.
- Conditions
- Atelectasis, Postoperative, Hypoxia, Critical Illness
- Trial name
- NCT06702813
- Testing
- High-Frequency Oscillatory Ventilation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shanghai Zhongshan Hospital
Postoperative Pulmonary Complications (PPCs), Hypoxemia
Lung Ultrasound Score and Postoperative Pulmonary Complications in Major Non-Thoracic Surgery
This prospective observational cohort study aims to evaluate the predictive value of perioperative lung ultrasound (LUS) score in determining early postoperative oxygen requirement and pulmonary complications in patients…
- Trial name
- LUS-POSTOP (NCT07515001)
- Volunteers
- 97 people
- Sponsor
- Dicle University
Coronary Artery Disease, Coronary Artery Bypass Grafting
Roxadustat and Myocardial Injury After Off-Pump Coronary Artery Bypass Surgery
Myocardial injury and infarction are common after cardiac surgery and are associated with worse perioperative outcomes. Hypoxia-inducible factor (HIF) is an important metabolic regulator that protects the myocardium.
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Hypoxia-Inducible Factor 1, Alpha Subunit, Prolyl-Hydroxylase Inhibitors
- Trial name
- NCT07912801
- Testing
- Roxadustat
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Hypoxemia, Ventilator Lung
Driving Pressure-guided Lung Protective Ventilation
The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving…
- Trial name
- DPV (NCT06361420)
- Testing
- Driving pressure-guided positive end expiratory pressure, Optimal oxygenation-guided positive end expiratory pressure, Ventilation strategy
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Yong Lin, PhD
Pulmonary Resection Surgery, One Lung Ventillation (OLV)
BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic Surgery
One-lung ventilation (OLV) is required during many thoracic surgical procedures and is associated with reduced functional residual capacity, atelectasis, ventilation-perfusion mismatch, hypoxemia, and potentially…
- Conditions
- Pulmonary Resection Surgery, One Lung Ventillation (OLV), General Anesthetic
- Trial name
- SIMPLE-PEEP (NCT07851740)
- Testing
- Fixed PEEP, BMI-adjusted PEEP
- Where
- 4 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Jesús Manuel Nieves Alonso
Hypoxemia
Reminder-enhanced Incentive Spirometry Evaluation
The purpose of this study is to test whether automatic reminders with a light and a soft sound help patients improve deep breathing exercises after surgery.
- Trial name
- RISE (NCT07728214)
- Testing
- Alarms ON
- Volunteers
- 88 people
- Sponsor
- University of Colorado, Denver
Hypoxemia
Preoperative ROX Index and Postoperative Hypoxemia in Bariatric Surgery
This prospective observational study evaluates whether the preoperative ROX index can predict early postoperative hypoxemia in patients undergoing bariatric surgery.
- Trial name
- NCT07303205
- Testing
- Preoperative ROX Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istinye University
Hypoxemia, Extubation
Postoperative Extubation in Hypoxemic Patients
The objective of this clinical trial is to assess whether early extubation of patients with hypoxemia during the spontaneous breathing trial (SBT) shortens the duration of ventilatory support.
- Conditions
- Hypoxemia, Extubation, Postoperative Respiratory Complication
- Trial name
- EPHYRE (NCT06688487)
- Testing
- early extubation of hypoxemic patients
- Where
- 12 sites in France
- Volunteers
- 152 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Post-Cardiac Arrest Syndrome, Post Cardiac Arrest Brain Injury
Cerebral Oximetry in Management of Post Cardiac Arrest
Resuscitation from a cardiac arrest is a common reason for admission to an intensive care unit (ICU). Because the brain is highly vulnerable to oxygen deprivation, severe brain damage often occurs during a cardiac arrest.
- Conditions
- Post-Cardiac Arrest Syndrome, Post Cardiac Arrest Brain Injury, Hypoxic-Ischemic Brain Injury
- Trial name
- COMPACT (NCT07829887)
- Testing
- Cerebral oximetry-guided treatment
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of Calgary
Out-of-Hospital Cardiac Arrest, Hypoxic-Ischemic Brain Injury
Minimal Sedation Versus Standard Continuous Sedation After Out-of-Hospital Cardiac Arrest
Most patients resuscitated from out-of-hospital cardiac arrest (OHCA) remain comatose on hospital admission and are routinely managed with continuous sedation.
- Conditions
- Out-of-Hospital Cardiac Arrest, Hypoxic-Ischemic Brain Injury, Post-Cardiac Arrest Syndrome
- Trial name
- NCT07895771
- Testing
- Minimal sedation, Standard continuous sedation
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Oxygen Deficiency
Postoperative SpO₂/FiO₂ in Obese and Non-Obese Patients: Role of STOP-BANG
The aim of this study is to evaluate the effect of the Reverse Trendelenburg position on oxygenation (SpO₂/FiO₂ ratio) in the early postoperative period in patients undergoing laparoscopic surgery.
- Trial name
- NCT07188649
- Testing
- oxygen deficiency
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istinye University
Achilles Tendon Rupture, Blood Flow Restriction Therapy
Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair
The goal of this clinical trial is to determine whether blood flow restriction resistance training (BFR-RT) improves postoperative muscle recovery and functional outcomes following primary surgical repair of acute Achilles tendon…
- Conditions
- Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
- Trial name
- NCT07498166
- Testing
- Blood Flow Restriction Resistance Training (BFR-RT), Standard Physical Therapy
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital