Clinical trials: Postoperative Ileus.
Postoperative Complications, Postoperative Gastrointestinal Dysfunction (POGD)
Abdominal Acupuncture for Gastrointestinal Function Recovery After Gynecologic Laparoscopic Surgery
Current research on the role of abdominal acupuncture in promoting postoperative gastrointestinal recovery remains limited, characterized by a lack of large-scale, standardized clinical trials, particularly with respect to…
- Conditions
- Postoperative Complications, Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus
- Trial name
- NCT07293026
- Testing
- Abdominal acupuncture, Standard postoperative management protocol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Mengyao Han
Ileus
Thoracic Epidural for Postoperative Ileus
The investigators try to find whether thoracic epidural analgesia (TEA) shortens the first gas-out time compared to iv-PCA and promotes earlier discharge after major upper abdominal surgery.
- Trial name
- NCT02491385
- Testing
- thoracic epidural analgesia, iv-PCA
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Samsung Medical Center
Complication, Postoperative
Early Initiation of Oral Feeding Versus Traditional Feeding Post Caesarean Section
Early initiation of oral feeding, within 6-12 hours post-caesarean section, has been noticed to be well tolerated by patients and helps them recover fast.
- Trial name
- NCT06539117
- Testing
- Early feeding post caesarean section
- Where
- Nigeria
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Postoperative Ileus, Colorectal Cancer
Role of Tibial Nerve Stimulation for Enhanced Postoperative Recovery After Colorectal Surgery
Aim of the study is to evaluate the role of postoperative tibial nerve stimulation in the enhancement of the recovery of bowel function and in shortening the hospital stay.
- Trial name
- TiRex (NCT02433938)
- Testing
- Tibial nerve stimulation
- Volunteers
- 160 people
- Sponsor
- University of Florence
Postoperative Ileus
The Effect of Hot Pack Application on Postoperative Ileus Undergoing Surgery for Gynecologic Malignancies
Postoperative ileus (POI), is an extensively known complication characterized by an impairment of normal gastrointestinal motor activity after abdominal surgery and may also occur after surgery at other sites due to…
- Trial name
- NCT04833699
- Testing
- rubber water bag
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Erzincan Military Hospital
Postoperative Ileus
A Tolerability and Efficacy Study of TU-100 For The Treatment of Postoperative Ileus
Postoperative ileus (POI), a transient impairment of gastrointestinal (GI) motility, commonly occurs in patients who have undergone abdominal surgery and contributes to postoperative morbidity, including delayed enteral…
- Trial name
- NCT00266461
- Testing
- Daikenchuto Extract Granules (TU-100)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Tsumura USA
Ileus, Post-Operative Adhesions
A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection
The purpose of this study is to establish preliminary evidence of the efficacy, safety, and tolerability of LB1148 for the treatment of post-operative ileus and intra-abdominal adhesions in subjects undergoing elective bowel…
- Trial name
- PROFILE (NCT02836470)
- Testing
- LB1148
- Where
- 28 sites in United States
- Volunteers
- 112 people
- Sponsor
- Palisade Bio
Rectal Cancer Surgery, Middle and Low Rectal Cancer
Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery
The goal of this clinical trial is to determine whether closing the pelvic floor peritoneum during laparoscopic radical resection of mid-low rectal cancer can reduce the incidence of postoperative ileus.
- Conditions
- Rectal Cancer Surgery, Middle and Low Rectal Cancer, Intestinal Obstruction, Ileus
- Trial name
- TOWER-1 (NCT07432542)
- Testing
- Pelvic floor peritoneum reconstruction
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Sun Yat-sen University
Ileus
Effect of Chewing Gum on Post-operative Ileus (GUMPI)
The purpose of this study is to determine whether chewing gum post-operatively decreases the time to first flatus or defecation in patients undergoing spine surgery as a indirect indicator of post-operative ileus.
- Trial name
- GUMPI (NCT02847364)
- Testing
- chewing gum
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Postoperative Ileus
Effect of TU-100 in Patients Undergoing Laparoscopic Colectomy
TU-100 is a gastrointestinal drug produced from the three botanical raw materials, Asian ginseng, Zanthoxylum fruit (Japanese pepper), and ginger, based on proprietary aqueous decoction and granulation technology.
- Trial name
- TU100P2T3 (NCT02232893)
- Testing
- Daikenchuto (TU-100)
- Where
- 13 sites in United States
- Volunteers
- 69 people
- Sponsor
- Tsumura USA
Gastrointestinal Cancer
Rocking Motion: Physiologic Effect on the Surgical Stress Response
After having abdominal surgery, patients often experience a lack of bowel function that can cause nausea, vomiting, abdominal swelling, pain, and/or discomfort.
- Trial name
- NCT01200316
- Testing
- Standard of Care, Rocking Chair Motion, Questionnaire
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- M.D. Anderson Cancer Center
Ileus Postoperative
The Effects of Combined Gum-chewing and Parenteral Metoclopramide on Post-operative Ileus
A delay in the return of bowel function is a common occurrence after abdominal surgeries.1 The goal of this study was to test the effect of the combined use of chewing a gum and administering metoclopramide intravenously on the…
- Trial name
- NCT05669781
- Testing
- Metoclopramide 10mg, Gum and metoclopramide, Gum
- Where
- Nigeria
- Volunteers
- 105 people
- Sponsor
- Ikechukwu Bartholomew Ulasi
Ileus
A New Approach of Neostigmine in Unavoidable Post Operative Ileus
Postoperative ileus (POI) in the absence of any mechanical obstruction remains a commonly encountered clinical problem.So, this study aimed to show the effective way to decrease the rate of postoperative Ileus (POI).
- Trial name
- NCT00676377
- Testing
- Neostigmine, Saline
- Where
- Iran
- Volunteers
- 3 people
- Sponsor
- Baqiyatallah Medical Sciences University
Postoperative Ileus
Does Coffee Consumption Prevent or Shorten Postoperative Ileus After Colon Resection?
The purpose of this study is to determine if consuming an 8 ounce cup of coffee with breakfast and lunch is effective in preventing or reducing postoperative ileus.
- Trial name
- NCT01130675
- Testing
- caffeinated coffee
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Massachusetts, Worcester
Colorectal Cancer
Effect of Intravenous Lidocaine on the Tolerability of Early Oral Feeding After Laparoscopic Colorectal Surgery
The purpose of this study is to determine whether intravenous lidocaine increase the tolerability of early oral feeding after laparoscopic colorectal surgery in patients with colorectal cancer. Degree of nausea/vomiting.
- Trial name
- NCT01346917
- Testing
- Lidocaine, Normal saline
- Where
- South Korea
- Volunteers
- 77 people
- Sponsor
- Kangbuk Samsung Hospital
Postoperative Ileus
Pilot Study: Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve
Hypothesis: Electrical stimulation of the abdominal vagus nerve has an anti-inflammatory effect and represents a new therapeutic approach to shorten postoperative ileus.
- Trial name
- NCT01572155
- Testing
- Vagus stimulation 1, Vagus stimulation 2
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- KU Leuven
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Postoperative Ileus, Gastrointestinal Cancer
Acupuncture for the Treatment of Postoperative Ileus After Gastrointestinal Surgery
The goal of this study is to learn if electro-acupuncture is a feasible treatment option for postoperative ileus after abdominal surgery.
- Trial name
- NCT04713241
- Testing
- Electro-acupuncture, Standard of Care Bowel rest
- Sponsor
- Case Comprehensive Cancer Center
Postoperative Gastrointestinal Dysfunction (POGD)
Drainage Fluid Biomarkers and Postoperative Gastrointestinal Dysfunction in Laparoscopic Colorectal Surgery
Postoperative gastrointestinal dysfunction (POGD), often referred to as postoperative ileus (POI) after colorectal surgery, is characterized by symptoms such as nausea, vomiting, abdominal distension, and delayed bowel movements.
- Trial name
- NCT06263101
- Testing
- Biochemical testing of abdominal drainage fluid, Cytological examination of abdominal drainage fluid, Peripheral blood cytology tests
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Chaoyang Hospital of China Medical University
Postoperative Ileus, Surgery-Complications
Intestinal Microbiota and Postoperative Ileus After Colorectal Surgery
Postoperative ileus (POI) after colorectal surgery is frequent and is a burden for national health authority because it increases the morbidity and the length of hospital stay.
- Trial name
- MICRO-IPO (NCT05512741)
- Testing
- Feces collection
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Angers