Clinical trials: Postoperative Ileus.
Post-operative Ileus
G-Tech Feasibility Study for Early Detection of a Post-op Ileus
This feasibility study is for the purpose of determining if the G-Tech Device can differentiate between normal return of GI activity post-operatively and the myoelectric activity in patients who develop a POI.
- Trial name
- GTECHPOI (NCT02673671)
- Testing
- G-Tech Myoelectric recording device
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- G-Tech Corporation
Postoperative Ileus, Postoperative Complications
Coffee After Pancreatic Surgery
Postoperative ileus is a common complication after major abdominal surgery. A positive effect of coffee to bowel movement has been described after colorectal and gynecologic interventions.
- Conditions
- Postoperative Ileus, Postoperative Complications, Bowel Dysfunction, Pancreatic Diseases
- Trial name
- COPS (NCT04205058)
- Testing
- Standard coffee, Caffeine-free coffee, Drinking water
- Where
- Italy
- Volunteers
- 204 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Ileus
Neurostimulation for the Treatment of Post-Operative Ileus
The primary goal of this study is to validate the design of the ElectroCore RMS-1100 Resolution Motility System™ and the ability to safely place a stimulation electrode in the epidural space of the spine in a post-operative…
- Trial name
- NCT00854074
- Testing
- ElectroCore RMS-1100 Resolution Motility System™
- Where
- 3 sites in United States
- Sponsor
- ElectroCore INC
Postoperative Ileus
Anti-inflammatory Effect of Pre-operative Stimulation of the Cholinergic Anti-Inflammatory Pathway
Hypothesis: Prucalopride can mimic electrical stimulation of the abdominal vagus nerve and has an anti-inflammatory effect. Aims: In the present pilot study, the investigators want to evaluate the anti-inflammatory effect of…
- Trial name
- NCT02425774
- Testing
- Vagus stimulation, Prucalopride
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- KU Leuven
Postoperative Ileus
Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery
The purpose of this study is to determine whether TZP-101 is effective in the management of post operative ileus in subjects undergoing major open abdominal surgery (i.e. partial large bowel resection).
- Trial name
- NCT00617552
- Testing
- 5% dextrose in water, TZP-101
- Where
- 27 sites in United States, India and 1 more
- Volunteers
- 267 people
- Sponsor
- Tranzyme, Inc.
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Ileus
Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/ Postoperative Ileus
Patients undergoing major abdominal surgery are at highest risk for developing postoperative ileus (POI), occurring in nearly all cases.
- Trial name
- NCT00388479
- Testing
- Alvimopan
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Postoperative Ileus
Tibial Nerve Stimulation and Postoperative Ileus
Postoperative ileus (POI) causes patient's discomfort and leads to an increase of cost of management after colorectal surgery because of an increase of the morbidity rate or of the rate of early rehospitalization after discharge.
- Trial name
- pre-TAPIOCA (NCT02815956)
- Testing
- percutaneous tibial nerve stimulation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Postoperative Ileus, Bowel Paralysis
Gastrointestinal Stimulation As a Treatment of Postoperative Ileus Following Extensive Surgery
The goal of this clinical trial is to investigate the effect of gastrointestinal stimulation with a pacemaker on the length of postoperative bowel paralysis in patients undergoing major abdominal surgery due to metastasizing…
- Trial name
- STIMULATE (NCT05752071)
- Testing
- Gastric electrical stimulation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Colorectal Cancer, Bowel Ileus
Efficacy of Mosapride on Recovery of Intestinal Motility After Elective Colorectal Cancer Surgery
Postoperative ileus (POI) is one of the most common causes of prolonged hospital stays after abdominal surgery. The pathophysiology of POI is multifactorial and complex.It is known to be associated with sympathetic neural…
- Trial name
- NCT04905147
- Testing
- Mosapride
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Mahidol University
Post-operative Ileus
Nicotine Gum Recovery After Colorectal Surgery
The purpose of this study is to evaluate whether the use of nicotine gum in the postoperative period influences surgical outcome in patients undergoing colorectal surgery.
- Trial name
- NCT01662115
- Testing
- Nicotine gum, Regular chewing gum
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The Cleveland Clinic
Colon Cancer, Splenic Flexure Mobilization
Surgical Outcomes in Splenic Flexure Cancers: A Multicenter Comparison of Segmental vs. Extended Hemicolectomy (SPARROW Study)
SPARROW Study: Surgical Outcomes in Splenic Flexure Cancer Colonic cancers located at the splenic flexure where the transverse colon turns into the descending colon are uncommon and represent less than 10% of all colorectal…
- Conditions
- Colon Cancer, Splenic Flexure Mobilization, Right Hemicolectomy, Left Hemicolectomy
- Trial name
- SPARROW (NCT07289568)
- Testing
- Colectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Acibadem University
Paralytic Ileus
Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy
A multicenter randomized-controlled trial of daikenchuto (TJ-100), a traditional Japanese herbal medicine (Kampo), to investigate its effect on intestinal dysmotility and for the prevention of postoperative paralytic ileus.
- Trial name
- JAPAN-PD (NCT01607307)
- Testing
- Oral/enteral TJ-100 solution
- Where
- 5 sites in Japan
- Volunteers
- 220 people
- Sponsor
- Wakayama Medical University
Ileus Postoperative, Gastrointestinal Function
Oral Lactulose for Gastrointestinal Recovery After Complex Appendectomy
This is a prospective, triple-blind, placebo-controlled, single-center randomized clinical trial to evaluate the efficacy and safety of early oral lactulose for promoting postoperative gastrointestinal functional recovery in…
- Conditions
- Ileus Postoperative, Gastrointestinal Function, Complicated Appendicitis
- Trial name
- NCT07589465
- Testing
- Lactulose oral solution
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanchong Central Hospital
Post-operative Ileus
Evaluating the Efficacy of Current Treatments for Reducing Postoperative Ileus
Aim was to investigate efficacy of current treatments - water, chewing gum, and olive oil, in resolving postoperative ileus.
- Trial name
- NCT01869231
- Testing
- olive oil, olive oil and chewing gum, chewing gum
- Where
- Italy
- Volunteers
- 360 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Post Operative Ileus
Alvimopan Use in Polytraumatized Patients
To evaluate the efficacy and safety of Alvimopan(12 mg) in recovery of bowel function in an emergency trauma setting without the pre-operative dosage in patients that will receive abdominal surgery.
- Trial name
- NCT03068975
- Testing
- Alvimopan
- Where
- Puerto Rico
- Volunteers
- 3 people
- Sponsor
- University of Puerto Rico
Postoperative Ileus
Effects of Chewing Gum Against Postoperative Ileus
The purpose of this study is to determine whether the use of chewing gum effects postoperative ileus after pancreaticoduodenectomy.
- Trial name
- NCT02319512
- Testing
- Chewing gum, Glucose
- Volunteers
- 65 people
- Sponsor
- Thomas Andersson
Postoperative Ileus
Electroacupuncture for Postoperative Ileus After Laparoscopic Rectal Cancer Surgery
Postoperative ileus remains a significant medical problem after colorectal surgery that adversely influences patients' recovery.
- Trial name
- NCT01844908
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Ileus, Bowel Obstruction
Stoma Tube Decompression and Postoperative Ileus After Major Colorectal Surgery
Postoperative ileus is common after colorectal surgery, occurring in up to 20% of patients. Stomas are frequently created in conjunction with major colorectal surgery.
- Trial name
- NCT01911793
- Testing
- Stoma Tube
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Ileus
Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery
A double blind, placebo controlled, randomized control trial studying the safety and efficacy of pyridostigmine as a rescue therapy for postoperative ileus.
- Trial name
- PESTI (NCT05334485)
- Testing
- Pyridostigmine Bromide
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stefan Holubar MD MS FACS, FASCRS