Clinical trials: Postoperative Infection of Incision
Abdominal Hernia
Light vs Heavy Weighted Mesh Repair in Primary Abdominal Hernia in Terms of Surgical Site Infection
This study compares the incidence of surgical site infections (SSI) in patients undergoing abdominal hernia repair using either light or heavy-weighted polypropylene mesh.
- Trial name
- NCT06644612
- Testing
- Light Weight Mesh, Heavy Weight Mesh
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Khyber Medical University Peshawar
Cesarean Section, Surgical Wound Infection
Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m²
Cesarean delivery is one of the most common surgical procedures in obstetric care. Women with obesity (body mass index [BMI] of 30 kg/m² or higher) are at increased risk for postoperative wound complications, including surgical…
- Conditions
- Cesarean Section, Surgical Wound Infection, Wound Healing, Obesity
- Trial name
- NCT07846930
- Volunteers
- 726 people
- Sponsor
- Assiut University
Surgical Site Infections
Review of Surgical Site Infection Registration Routine at Surgery Departments in Sweden and Validation of One of the Used Routines
This study explores the routines of registration of surgical site infections (SSI) at different surgical centers in Sweden. It explores the sensitivity and specificity of the registration routines of SSI are at Halmstad County…
- Trial name
- NCT01971138
- Testing
- this is a survey
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Halmstad County Hospital
Colorectal Cancer, Incisional Hernia
Comparing Polypropylene Mesh and "Small Bites" Technique in Emergency Colorectal Surgery's Midline Laparotomy Closure. Study for Incisional Hernia Prevention.
The 2023 World Journal of Emergency Surgery guidelines couldn't provide a recommendation for emergency abdominal wall closure due to insufficient consensus (>80% required).
- Conditions
- Colorectal Cancer, Incisional Hernia, Wound Infection
- Trial name
- BITEME (NCT06220058)
- Testing
- Closure of the midline laparotomy using the "small bites" technique, Closure of the midline laparotomy using the "small bites" technique with an absorbable PP mesh
- Where
- Spain
- Volunteers
- 148 people
- Sponsor
- Fernandez Zamora
Surgical Wound Infection
Relation of Skin Closure Method to Groin Wound Infections After Proximal Femoral Artery Exposure.
This study aims to asses whether the rate of surgical wound infections in vascular surgery procedures involving exposure of the proximal femoral artery can be reduced using a different skin closure technique.
- Trial name
- NCT03468621
- Testing
- Wound closure
- Where
- 3 sites in Finland
- Volunteers
- 300 people
- Sponsor
- Turku University Hospital
Surgical Wound Infection
Circular pOlyethylene Drape in preVention of Surgical Site infEction: A Randomized Controlled Trial
This study is to evaluate the effectiveness of the plastic ring wound retractor to reduce the rate of surgical site infection in patients who undergo open abdomen surgery for gastrointestinal tract.
- Trial name
- COVER (NCT03170843)
- Testing
- use of plastic ring wound retractor
- Where
- 13 sites in South Korea
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Saint Vincent's Hospital, Korea
Surgical Site Infections
Efficacy Study of Mupirocin on Infection After Coronary Artery Bypass Grafting
The hypothesis is that application of Mupirocin to the nose before and after coronary artery bypass grafting surgery will reduce the incidence of surgical site infections.
- Trial name
- MIR-CABG (NCT01949935)
- Testing
- Mupirocin
- Where
- Canada
- Volunteers
- 974 people
- Sponsor
- Horizon Health Network
Surgical Site Infection
Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
Many strategies have been attempted to reduce SSI rates. The Centers for Medicare and Medicaid Services introduced the Surgical Care Improvement Project infection project with the aim of reducing SSI incidence and morbidity.
- Trial name
- NCT02509260
- Testing
- Prevena wound management system, Standard wound dressings
- Where
- United States
- Volunteers
- 298 people
- Sponsor
- The Cleveland Clinic
Surgical Site Infection, Antibiotic Prophylaxis
The Role of Guideline-adherent Perioperative Antibiotic Administration and the Risk of Surgical Site Infections After Non-cardiac Surgery.
This study will seek to describe current practice of antibiotic prophylaxis to identify the effect of appropriate perioperative antimicrobial coverage - specifically regarding timing, dose adjustments, and redosing - on surgical…
- Trial name
- NCT03982810
- Testing
- Antibiotics
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Staphylococcus Aureus, Surgical Wound Infection
Advanced Understanding of Staphylococcus Aureus Infections in Europe - Surgical Site Infections
ASPIRE-SSI is a prospective, observational, multicentre cohort study among adult surgical patients, which aims to determine the incidence of healthcare-associated S. aureus infections, particularly S.
- Trial name
- ASPIRE-SSI (NCT02935244)
- Where
- 33 sites in Belgium, Czechia and 8 more
- Volunteers
- 5,004 people
- Sponsor
- UMC Utrecht
Surgical Site Infection
Wound Infection in Obese Women After Cesarean Delivery
The purpose of this study is to determine the surgical site infection rate and patient satisfaction for absorbable versus non absorbable suture in closure of skin at cesarean section in obese women.
- Trial name
- NCT01679379
- Testing
- Absorbable suture group, Non absorbable suture group
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Colorectal Neoplasms, Surgical Wound Infection
Reduction of Surgical Site Infections in Elective Colorectal Surgery After the Implementation of a Bundle of Care.
Background. The Nosocomial Infection Surveillance Program in Catalonia (VINCat) monitors SSI in elective colorectal surgery since 2007 in 56 hospitals (7.5 million population).
- Trial name
- NCT04129177
- Testing
- Implementation of a bundle of surgical infection preventive measures
- Where
- Spain
- Volunteers
- 12,000 people
- Sponsor
- Hospital de Granollers
Surgical Wound Infection
Local Gentamicin Application to Reduce Postoperative Infection Rate
The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of…
- Trial name
- NCT01287780
- Testing
- Collagen-gentamicin sponge
- Where
- 5 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
Surgical Site Infection, Antibiotics Prophylaxis
Cefuroxime vs Ceftriaxone for SSI Prevention in Neurosurgery
BACKGROUND: Surgical site infection (SSI) is potentially catastrophic in neurosurgical procedures, causing poor in-hospital outcomes in more than half of those affected and significantly increased length of hospital stay.
- Trial name
- NCT05398081
- Testing
- Cefuroxime (Zinnat®), Ceftriaxone (Rocephin®)
- Where
- Nigeria
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Dr. Promise Tamunoipiriala Jaja
Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical
Effect of Continuous Versus Interrupted Suturing on Wound Dehiscence and Infection After Abdominal Surgery
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical, Dehiscence of Laparotomy Wound, Suture, Interrupted
- Trial name
- NCT07241507
- Testing
- Continuous suturing, Interrupted suturing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Allama Iqbal Teaching Hospital
Open Fracture, Post-Op Wound Infection
Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens
To demonstrate noninferiority of three different empiric antimicrobial regimens compared to the traditional antimicrobial regimen for the management of grade III open fractures as well as evaluate outcomes among these groups.
- Trial name
- NCT03560232
- Testing
- Ceftriaxone, Ampicillin/sulbactam, Piperacillin/tazobactam
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Mercy Health Ohio
Operation Wound; Infection, Endometritis
Use of Antiseptic Solution for Vaginal Wash Before Cesarean Section
To evaluate the rate of infections after cesarean sections in patients with premature rupture of membranes after vaginal wash either with an antiseptic solution (clorhexidine solution) vs. saline solution (placebo).
- Trial name
- NCT03442218
- Testing
- Clorhexidine, Saline solution
- Where
- Panama
- Volunteers
- 203 people
- Sponsor
- Saint Thomas Hospital, Panama
Surgical Site Infection, Closed Suction Drains
Bacterial Colonization of Suction Drains Following Spine Surgery
Closed suction drains are commonly used following surgery, if the wound is expected to discharge significant amounts of fluid. To this date, no evidence base exists as to the exact post operative time period or discharge volume…
- Trial name
- NCT01803490
- Where
- Israel
- Volunteers
- 224 people
- Sponsor
- Western Galilee Hospital-Nahariya
Coronary Artery Disease, Valvular Heart Disease
Efficacy of Sternum Guard in Post Cardiac Surgery Patient
This is a single-center, single-blind, randomized parallel superiority trial comparing two groups; Sternum GuardTM as the treatment arm and Bone Wax as the active control group.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Congenital Heart Disease in Adolescence, Post Operative Wound Infection
- Trial name
- NCT05229276
- Testing
- Sternum Guard, Bone Wax
- Where
- Indonesia
- Volunteers
- 414 people
- Sponsor
- Universitas Indonesia