Clinical trials: Postoperative Infection of Incision
Surgery, Nasal Disease
Assessing the Efficacy of Photodynamic Therapy for Preventing Surgical Site Infections
This is a randomised, unblinded interventional device proof of concept pilot trial in which patients undergoing nasal surgery will be selected for either photodisinfection therapy (PDT) with the Steriwave™ ND System, or control…
- Conditions
- Surgery, Nasal Disease, Light; Therapy, Complications
- Trial name
- LIGHT (NCT06731881)
- Testing
- Nasal PDT, Photosensitizer formulation only, Standard follow-up
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Surgical Site Infection, Wound Heal
The Efficacy of Purse-string Skin Closure With Negative Pressure Wound Therapy (NPWT) After Ileostomy Reversal
Evaluating the effectiveness of the existing 'linear suture + wound drain placement' and 'purse-string suture + negative pressure wound therapy' through a prospective comparative study
- Trial name
- NCT04986111
- Testing
- Linear skin closure with wound drain, Purse-string skin closure with negative pressure wound therapy
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Seoul National University Bundang Hospital
Bariatric Surgery Candidate
The Effect of the Care Bundle to be Applied to Obesity Surgery Patients on Surgical Site Infection and Patient Comfort
One of the most effective treatment methods of obesity is surgery. Bariatric surgery is classified as a clean-contaminated wound. The expected benefit from surgery is weight loss.
- Trial name
- NCT05930639
- Testing
- Surgical Site Infection (SSI) prevention package
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Malatya Turgut Ozal University
Thyroid Diseases, Wound Healing
Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control
The goal of this clinical trial is to evaluate the therapeutic efficacy and safety of non-thermal plasma (NTP) as an adjuvant treatment for surgical bed decontamination and accelerated tissue repair in patients undergoing total…
- Conditions
- Thyroid Diseases, Wound Healing, Thyroidectomy, Surgical Wound Infection
- Trial name
- NCT07382973
- Testing
- Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Post-Op Complication, Spine Surgery
Irrisept Solution for Instrumented Spine Surgery
Various spine surgeons perform wound irrigation using saline mixed with vancomycin, relying on mechanical debridement of non-viable tissue, physical disruption of biofilm, and bacteriostatic effect against gram positive flora.
- Conditions
- Post-Op Complication, Spine Surgery, Site Infection, Surgical Site Infection
- Trial name
- NCT06439953
- Testing
- Chlorhexidine gluconate solution, Vancomycin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rhode Island Hospital
Colorectal Neoplasms, Surgical Wound Infection
Reduction of Surgical Site Infections in Elective Colorectal Surgery After the Implementation of a Bundle of Care.
Background. The Nosocomial Infection Surveillance Program in Catalonia (VINCat) monitors SSI in elective colorectal surgery since 2007 in 56 hospitals (7.5 million population).
- Trial name
- NCT04129177
- Testing
- Implementation of a bundle of surgical infection preventive measures
- Where
- Spain
- Volunteers
- 12,000 people
- Sponsor
- Hospital de Granollers
Late Effects of Surgery, Staphylococcus Aureus
Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery
This investigation is a prospective, open-label pharmacokinetic study of daptomycin prophylaxis in patients undergoing coronary artery bypass graft surgery without valvular replacement.
- Conditions
- Late Effects of Surgery, Staphylococcus Aureus, Surgical Site Infection
- Trial name
- NCT00701636
- Testing
- daptomycin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Surgical Wound Infection
Post Cesarian Section Wound Infections At Emergency Room
The goal of this observational study is to compare the incidence of post-cesarean section wound infections between emergency and elective cesarean deliveries at El-hussien Hospital.
- Trial name
- NCT06491381
- Testing
- Cesarean delivery
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Al-Azhar University
Surgical Site Infection
Surgical Site Infection Rates in Obese Patients After Cesarean Delivery
The aim of this study is to determine the surgical site infection rate and patient satisfaction for subcuticular versus interrupted mattress suture in closure of skin at Cesarean delivery in obese patients.
- Trial name
- NCT01713751
- Testing
- Interrupted suturing, Subcuticular suturing
- Volunteers
- 500 people
- Sponsor
- Ain Shams University
Surgical Wound Infection
Determining the Worldwide Epidemiology of Surgical Site Infections After Gastrointestinal Surgery
Surgical site infection (SSI) is the most common complication following major gastrointestinal surgery, affecting between 25-40% of patients.
- Trial name
- GlobalSurg 2 (NCT02662231)
- Testing
- Emergency, or elective gastrointestinal resection
- Where
- 2 sites in United Kingdom
- Volunteers
- 12,539 people
- Sponsor
- University of Edinburgh
Surgical Wound Infection
Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection in Herniated Disk Surgery
The purpose of the study is to determine whether a single, pre-operative dose of cefuroxime is effective in preventing surgical site infection in patients undergoing surgery for herniated disk
- Trial name
- NCT00530400
- Testing
- cefuroxime
- Where
- 2 sites in Switzerland
- Volunteers
- 1,369 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Surgical Wound Infection
A Randomized Controlled Trial Exploring the Ability of Negative Pressure Wound Therapy (NPWT) to Reduce Colorectal Surgical Site Infections (SSI)
The study will explore the ability of negative pressure wound therapy (Prevena dressing) to reduce post operative superficial surgical site infection rate in elective colorectal surgery.
- Trial name
- NCT02348034
- Testing
- Prevena Dressing
- Where
- 3 sites in Canada
- Volunteers
- 126 people
- Sponsor
- University of Saskatchewan
Surgical Site Infections
Safety, Efficacy and Tolerability Study of up to 20 mL of DFA-02 in Patients Undergoing Abdominal Surgery
This is a randomized, blinded, placebo and standard of care controlled study of the efficacy of a novel antibiotic containing gel compared to placebo gel in preventing surgical site infection after abdominal surgery.
- Trial name
- NCT01888367
- Testing
- DFA-02 Antibiotic Gel
- Where
- 31 sites in United States
- Volunteers
- 445 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Femur Fracture, Periprosthetic Fracture of Hip
Dose-Response Association Between Cerclage Wire Number and Infection Risk
The purpose of this dual-center retrospective study is to investigate the relationship between the number of metallic cerclage wires used in femoral fracture surgery and the risk of developing deep infections.
- Conditions
- Femur Fracture, Periprosthetic Fracture of Hip, Periprosthetic Fracture of the Femur, Surgical Site Infection (SSI)
- Trial name
- C-INFECT (NCT07434258)
- Testing
- 1 Metallic Cerclage Wiring, 2 metalic cerclage wire, 3 metalic cerclage wire
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Surgical Site Infection
Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections
The purpose of this study was to compare the rate of surgical site infections in patients randomized to Irrisept versus SoC, who had an open abdominal laparotomy for abdominal trauma or acute surgical abdomen.
- Trial name
- NCT02255487
- Testing
- IrriSept System, No Intervention - Standard of Care (SoC) only
- Where
- 17 sites in United States
- Volunteers
- 627 people
- Sponsor
- Irrimax Corporation
Surgical Site Infections, Hypothermia
Feedback on Perioperative Temperature Management and Patient Outcomes: Three-arm Trial to Compare Feedback
The investigators aim to assess the impact of benchmarked and ranked feedback on anesthesiologists' perioperative temperature management and subsequent patient outcomes.
- Trial name
- NCT02414191
- Testing
- Benchmarked Feedback, Ranked Feedback
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Surgical Site Infection, Hip Fractures
Wound Contamination During Orthopaedic Surgery
In the present study we will compare bacteriological findings and the incidence of SSI in relation to laminar airflow (LAF) ventilated ORs, conventional (also called displacement or mixed) ventilated ORs and conventional…
- Conditions
- Surgical Site Infection, Hip Fractures, Orthopedic Disorder, Implant Infection
- Trial name
- Clean Care (NCT04676841)
- Testing
- Conventional ventilation + instrumental tables with integrated laminar airflow, Conventional ventilation + standard instrumental tables, Laminar airflow ventilation + standard instrumental tables
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Vastra Gotaland Region
Rectal Cancer, Organ-Space Surgical Site Infection
Concordance Between Monitoring Systems for Organ/Space Surgical Site Infections in Rectal Surgery
The Catalan Cancer Plan (CCP) undertakes periodic audits of cancer treatment outcomes, including organ/space surgical site infections (O/S-SSI) rates, while the Catalan Healthcare-associated Infections Surveillance Programme…
- Trial name
- NCT06104579
- Testing
- Person-level linkage of both databases looking for concordance in the diagnosis of organ-space surgical site infection
- Where
- Spain
- Volunteers
- 11,367 people
- Sponsor
- Hospital de Granollers
Surgical Site Infection
Application of Hyperoxygenated Fatty Acids in a Surgical Wound After Laparoscopic Cholecystectomy.
TITLE: Application of hyperoxygenated fatty acids (PrevOmega) in a surgical wound of the umbilical trocar after laparoscopic cholecystectomy with placement of prostheses in patients with risk factors.
- Trial name
- NCT04341805
- Testing
- PrevOmega, Physiological saline
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Surgical Site Infection
Wound Infection in Obese Women After Cesarean Delivery
The purpose of this study is to determine the surgical site infection rate and patient satisfaction for absorbable versus non absorbable suture in closure of skin at cesarean section in obese women.
- Trial name
- NCT01679379
- Testing
- Absorbable suture group, Non absorbable suture group
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University