Clinical trials: Postoperative Insomnia
Hip Fractures
Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality
1. Eligible patients are randomly divided into experimental and control groups； 2. The experimental group is given esketamine combined with dexmedetomidine，while the control group is given normal saline； 3.
- Trial name
- NCT07002723
- Testing
- Esketamine combined with dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University Shenzhen Hospital
Rectal Cancer, Low Anterior Resection Syndrome
Impact of Quality of Life in the Patients With Sleep Disturbance From Low Anterior Resection Syndrome in Advanced Rectal Cancer Patients
The preservation surgery of the anal sphincter has become a standard procedure for the treatment of rectal cancer and is now possible even when the tumor is close to the anus, thanks to the advancement of surgical techniques.
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, Insomnia
- Trial name
- NCT06271629
- Testing
- Insomnia severity index
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Intertrochanteric Fractures, Hip Fractures
Liposomal Bupivacaine Fascia Iliaca Block for Perioperative Sleep Quality in Elderly Patients With Intertrochanteric Fracture
Older adults with hip fracture often experience severe pain before and after surgery. This pain can cause anxiety and poor sleep, and may increase the risk of postoperative delirium (sudden confusion after surgery).
- Conditions
- Intertrochanteric Fractures, Hip Fractures, Sleep Disturbance, Postoperative Delirium
- Trial name
- NCT07892859
- Testing
- Liposomal Bupivicaine, Saline Solution (NaCl 0,9%)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Li Xiaoyuan
Pain, Postoperative
Effects of Lavender Oil on Postoperative Pain, Sleep Quality and Mood
This project will evaluate the integration of lavender essential oil in surgical patients during the perioperative and postoperative phase of care. The study will assess patients' pain, sleep quality, and mood.
- Trial name
- NCT03093454
- Testing
- Lavender Essential Oil
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Scott Hollenbeck, MD
Pain, Postoperative, Shoulder Pain
Comparing Mindfulness-based Breath Training and Heart Rate Variability Biofeedback for Shoulder Surgery Patients in the Postoperative Pain.
Although shoulder surgeries can effectively relieve pain intensity and restore shoulder function, some patients reported persistent post-operative pain at the 6-month post-surgery follow-up visit.
- Trial name
- NCT05917262
- Testing
- Mindfulness-based breathing, HRV biofeedback, cognitive-behavioral pain psychoeducation
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Pain, Preoperative Sleep Quality
The Effect of Sleep Quality Before Breast Surgery on Postoperative Pain
This study aimed to investigate the relationship between preoperative sleep quality and postoperative pain in patients undergoing mastectomy or breast-conserving surgery under general anesthesia.
- Trial name
- NCT07892924
- Testing
- Sleep Quality and Postoperative Pain Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Cystic Adenomatoid Malformation of Lung, Congenital, Bronchopulmonary Sequestration
Effect of Ultrasound-guided Erector Spinae Plane Block on Postoperative Pain and Sleep Quality of Infants With Congenital Pulmonary Cystic Disease After Thoracoscopic Surgery
This study intends to evaluate the effect of erector spinae plane block on postoperative analgesia and sleep quality in infants with congenital cystic pulmonary disease after thoracoscopic surgery, and provides reference for…
- Conditions
- Cystic Adenomatoid Malformation of Lung, Congenital, Bronchopulmonary Sequestration, Bronchogenic Cyst
- Trial name
- NCT06498583
- Testing
- Ropivacaine, erector spinae plane block, Incision infiltration of local anesthesia
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Lei Xiaoming
Total Knee Arthroplasty (TKA)
Effect of Preoperative Sleep Disturbance on Postoperative Pain and Recovery
The study subjects consisted of patients who underwent elective total knee arthroplasty (TKA) at Gansu Provincial Hospital of TCM from November 2023 to January 2024.
- Trial name
- NCT06815744
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Gansu Provincial Hospital
Sleep Quality of Patients Undergoing TURP
Postoperative Sleep Quality of Patients Sedation With i.v. Dexmedetomidine or Midazolam Undergoing TURP
The investigators designed a study to determine whether dexmedetomidine versus midazolam combined with spinal anesthesia would provide same postoperative sleep quality in patients undergoing transurethral prostatic resection.
- Trial name
- NCT02142595
- Testing
- dexmedetomidine, Midazolam
- Where
- China
- Volunteers
- 111 people
- Sponsor
- China Medical University, China
The Effect of Preoperative Administration of Oral Tizanidine, Post Operative Pain
The Effect of Preoperative Administration of Oral Tizanidine on the Postoperative Pain and Sleep Quality
The majority of lower limb fractures treated with surgery often leading to significant morbidity and mortality. Despite improvements in perioperative care, about 20% suffer from severe postoperative complications.
- Trial name
- Tizanidine (NCT07800364)
- Testing
- Tizanidine
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Tanta University
Sex Differences, Postoperative Sleep Quality
Sex Difference Effects on Postoperative Sleep, Inflammation and Cognition in Patients Undergoing General Anesthesia
Video-Assisted Thoracoscopic Surgery(VATS) is among the most common and disabling persistent pain and inflammation conditions, with increasing prevalence in the developed world, and affects women to a greater degree than men.
- Conditions
- Sex Differences, Postoperative Sleep Quality, Postoperative Pain, Inflammation Function
- Trial name
- NCT05059548
- Testing
- Video-Assisted Thoracoscopic Surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Rotator Cuff Tears
Effect of Gabapentin on Sleep and Opioid Use Following Rotator Cuff Repair
The goal of this clinical trial is to compare the effects of gabapentin in patients undergoing rotator cuff repair surgery. The main question it aims to answer is whether gabapentin can improve postoperative pain and sleep…
- Trial name
- NCT05800847
- Testing
- Gabapentin
- Volunteers
- 130 people
- Sponsor
- Hughston Clinic
Uterine Fibroids (UF)
Ultrasound-Guided Stellate Ganglion Block Plus Propofol for Perimenopausal Insomnia With Anxiety
Laparoscopic myomectomy is a commonly performed minimally invasive gynecologic procedure. However, surgical trauma, tracheal intubation, and pneumoperitoneum may induce pronounced perioperative stress responses, resulting in…
- Trial name
- SGB-PROP-PIA (NCT07384468)
- Testing
- Ultrasound-Guided Stellate Ganglion Block
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Xiaochen Ji
Sleep Disorder
Postoperative Sleep Quality and Pain of Patients After Video-Assisted Thoracoscopic Surgery
The goal of this clinical trial is to to explore the effect of perioperative transcutaneous acupoint acupuncture and moxibustion stimulation on sleep quality and postoperative chronic pain in patients undergoing thoracoscopic…
- Trial name
- PSQ (NCT06633432)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Postoperative Pain
Preoperative Versus Postoperative Ultrasound-guided Rectus Sheath Block for Sleep Quality and Cytokines of Patients
Rectus sheath block (RSB) is used for postoperative pain relief in patients undergoing abdominal surgery with a midline incision.
- Trial name
- NCT02477098
- Testing
- preoperative 0.5% ropivacaine hydrochloride preoperative, postoperative 0.5% Ropivacaine hydrochloride
- Where
- China
- Volunteers
- 77 people
- Sponsor
- China Medical University, China
Postoperative Sleep Disturbance, Thoracoscopic Surgery
Lemborexant on Perioperative Sleep Quality in Patients Undergoing Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is the mainstream minimally invasive procedure in thoracic surgery; However, the high-stress state during the perioperative period and severe postoperative pain often lead to…
- Trial name
- NCT07811401
- Testing
- Lemborexant 5 mg
- Volunteers
- 130 people
- Sponsor
- Beijing Tiantan Hospital
Chronic Post-Surgical Pain
Effect of Perioperative Sleep Quality on Chronic Post-Surgical Pain
The goal of this prospective observational cohort study is to assess the impact of perioperative sleep quality on the development of chronic post-surgical pain (CPSP) in adult patients (aged 18-80 years, ASA I-III) undergoing…
- Trial name
- NCT06871891
- Where
- China
- Volunteers
- 1,138 people
- Sponsor
- Peking Union Medical College Hospital