Clinical trials: Postoperative Outcomes
Cognitive Impairment, Frail Elderly Syndrome
Preoperative Cognitive Screening in Older Spinal Surgical Patients
The objectives of this study are to determine whether identifying patients with baseline cognitive deficits or frailty predict postoperative delirium.
- Trial name
- NCT02922634
- Testing
- Mini Cog
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
High-risk, Non-cardiovascular Surgeries
Esmolol for Treatment of Perioperative Tachycardia
The purpose of this study is to find out if Esmolol is a safe and effective alternative treatment compared to standard treatment using a long acting beta blocker drug, in controlling abnormal heart rate before, during and…
- Trial name
- NCT01208402
- Testing
- Esmolol
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Duke University
Rotator Cuff Tears, Hemorrhage, Surgical
Effect of Intravenous Tranexamic Acid on Visual Clarity During Shoulder Arthroscopy in the Beach Chair Position
Shoulder arthroscopy offers numerous advantages and has led to a continuous increase in procedural complexity. Adequate intraoperative visual clarity is essential for successful performance of the procedure and is primarily…
- Conditions
- Rotator Cuff Tears, Hemorrhage, Surgical, Shoulder Injuries
- Trial name
- NCT05397652
- Testing
- Tranexamic Acid Injectable Product
- Where
- Croatia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Nikola Matejcic
Meniscus Disorder, Meniscus, Torn Tibial
Blood Flow Restriction After Meniscus Repair
The purpose of this study is to evaluate post-operative outcomes after meniscus surgery in participants undergoing blood flow restriction training as a rehabilitative adjunct compared to those with standard rehabilitation.
- Conditions
- Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial
- Trial name
- NCT04436523
- Testing
- Blood flow restriction (Delfi Personalized Tourniquet System), Standard rehabilitation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Pain
Utility of Pharmacogenomic Testing and Postoperative Dental Pain Outcomes
Opioid analgesics are the most common postoperative pain medications used among dentists in the United States.Although these medications are highly effective in the postoperative dental pain management, not all patients optimally…
- Trial name
- NCT02932579
- Testing
- Pharmacogenomic Testing, Ibuprofen, hydroxycontin/acetominophen
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Phantom Limb Pain
Mixed Reality Based System to Manage Phantom Pain Phantom Pain for Patients With Lower Limb Amputation
The primary goals of this pilot research project are a) to design and develop the a mixed reality based system for managing phantom pain and b) to evaluate the feasibility and preliminary functional outcomes of this system in a…
- Trial name
- MrMAPP (NCT04529083)
- Testing
- Mr. MAPP
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Dallas VA Medical Center
Laminectomy
The Effects of Ketamine and Methadone on Postoperative Pain for Laminectomy
The purpose of this research is to determine the pain-reducing effects of ketamine (Ketalar, an FDA-approved drug for anesthesia) and methadone (Dolophine, a long-acting narcotic) after lumbar laminectomy.
- Trial name
- NCT02252432
- Testing
- Ketamine, Methadone, Ketamine + methadone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Cedars-Sinai Medical Center
Kidney Calculi
Stone Access and Removal (STAR) Study
The purpose of the study is to assess procedural completion, the post-operative stone clearance and the safety profile following robotic mini-Percutaneous Nephrolithotomy (PCNL) performed with the MONARCH Platform, Urology.
- Trial name
- STAR (NCT06330701)
- Testing
- Robotic-assisted mini-PCNL
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Auris Health, Inc.
Ventral Hernia, Hernia
Pilot Trial of Abdominal Core Rehabilitation To Improve Outcomes After Ventral Hernia Repair
This study aims to evaluate the potential role of physical therapy in improving outcomes after ventral hernia repair.
- Conditions
- Ventral Hernia, Hernia, Herniorrhaphy, Abdominal Wall
- Trial name
- ABVENTURE-P (NCT05142618)
- Testing
- Supervised Physical Therapy, Post-operative Precautions
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Ohio State University
Cataract
A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.
This is a prospective, multi-center, masked, three-arm, randomized clinical study of the TECNIS Eyhance Toric II IOL (test #1) and TECNIS Synergy Toric II (test #2) compared to the TECNIS Toric 1-Piece IOL (control).
- Trial name
- NCT05396599
- Testing
- Model DIU, Model DFW, Model ZCT
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Prostate Cancer
Platelet Rich Plasma During Radical Prostatectomy
Can platelet rich plasma applied to nerve bundles at time of surgery help the nerve bundles heal? Subjects undergoing a Radical Prostatectomy who meet study inclusion/exclusion criteria will be consented to receive an…
- Trial name
- NCT02957149
- Testing
- Autologous Platelet-Rich Plasma, Angel Concentrated Platelet Rich Plasma System
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Pain, Postoperative
Preoperative IV Versus Oral Acetaminophen
The current study proposes to examine whether there is a significant difference in patient outcomes related to the administration route of preoperative Acetaminophen.
- Trial name
- NCT03468920
- Testing
- IV Acetaminophen, PO Acetaminophen
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- TriHealth Inc.
Hernia, Ventral Hernia
Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair Scenarios
This prospective, single-arm clinical study evaluates the safety, feasibility, and early clinical outcomes of High-Purity Type I Collagen (HPTC; Surgicoll-Mesh®) when used as a biologic reinforcement in selected hernia repair…
- Conditions
- Hernia, Ventral Hernia, Incisional Hernia, İnguinal Hernia
- Trial name
- NCT07360691
- Testing
- High-Purity Type I Collagen Mesh
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Spine Surgery
Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery
The purpose of this study is determine if epidural anesthesia administered after surgery or lidocaine administered during surgery will decrease inflammation after spinal surgery and decrease the need for post operative pain…
- Trial name
- NCT00840996
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- The Cleveland Clinic
Post Operative Pain, Recurrence
Video-assisted Anal Fistula Treatment Versus Seton in the Management of High Peri Anal Fistula
Anal fistula is the most common Peri anal disease. It's a disease with an incidence of 9 in 100,000. Anal fistula is classified on the basis of its location into high and low anal fistula, above or below dentate line…
- Trial name
- NCT02313597
- Testing
- SETON, VAAFT
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Dr. SamiUllah
Femoro Acetabular Impingement, Pain, Postoperative
Outcomes of CPM Usage Following Arthroscopic Acetabular Labral Repair
The purpose of this study is to measure whether CPM (continuous passive motion) usage improves outcomes following arthroscopic hip surgery that includes labral repair.
- Conditions
- Femoro Acetabular Impingement, Pain, Postoperative, Hip Labral Tear
- Trial name
- NCT03407612
- Testing
- Continuous Passive Motion
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Ohio State University
Knee Meniscus Tear
A Prospective, Post-market, Multi-center Feasibility Study of the BioDuct® Meniscal Repair Device
To demonstrate repair of the meniscus at 6 months, as evaluated by MRI, will be observed; and clinical qualitative assessments will improve from preoperative to postoperative time points with the BioDuct® Meniscal Repair Device.
- Trial name
- NCT01270919
- Testing
- BioDuct Meniscal Repair Device
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- Stryker Orthopaedics
Acquired Antithrombin III Deficiency, Coronary Artery Bypass
Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass
The purpose of this trial is to study the effects of preoperative antithrombin supplementation in patients undergoing cardiac surgery with cardiopulmonary bypass in order to maintain antithrombin levels in a range greater than…
- Trial name
- NCT00823082
- Testing
- Antithrombin III
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Instituto Grifols, S.A.
Cesarean Section
Cesarean Section Via Enhanced Recovery
Enhanced Recovery After Surgery (ERAS) protocols have been proven to be very successful in specific patient populations. An example is with ERAS for colorectal surgery.
- Trial name
- NCT03552822
- Testing
- ERAS Protocol Implementation
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Colorectal Surgery
Effect of Ketamine on Postoperative Clinical Outcomes
The purpose of this research is to evaluate the effectiveness of ketamine as an analgesic adjuvant in decreasing the narcotic (opioids) analgesics during surgery, on pain management and on the later recovery after surgery in…
- Trial name
- NCT01365195
- Testing
- Ketamine high-dose, Ketamine low-dose
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Cedars-Sinai Medical Center