Clinical trials: Postoperative Pain
Knee Replacement, Total, Pain, Postoperative
Two Different Blocks for Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty
The frequency of femoral nerve block and adductor canal block for analgesia after TKA(total knee arthroplasty) increases with the use of ultrasonography in regional anesthesia.
- Conditions
- Knee Replacement, Total, Pain, Postoperative, Anesthesia, Regional
- Trial name
- NCT04286035
- Testing
- Bupivacaine Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Total Knee Arthroplasty
Dexamethasone in Total Knee Arthroplasty
The purpose of this study is to determine the most efficacious and safest dexamethasone dose given intraoperatively during total knee arthroplasty that reduces postoperative opioid consumption and pain, improves postoperative…
- Trial name
- NCT05018091
- Testing
- Dexamethasone 4mg, Dexamethasone 8 Mg/mL Injectable Suspension, Dexamethasone 16mg
- Where
- 10 sites in United States
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Pain Management, Anaesthesia Complication
Efficacy of Variable Volume Truncal Blocks in Upper Limb Orthopedic Surgery
aim of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist…
- Trial name
- NCT06664203
- Testing
- Selective turuncus block with 25 ml bupivacain, Selective turuncus block with 15 ml bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Moderate to Severe Acute Postoperative Pain
Evaluate the Safety and Efficacy of HL-1186 Tablet for Moderate to Severe Acute Pain After Surgery
This is a multiple-center, randomized, double-blind, placebo-controlled study design evaluating the safety, efficacy, and pharmacokinetics (PK) parameter of HL-1186 tablet for moderate to severe acute pain after surgery.
- Trial name
- NCT07147049
- Testing
- HL-1186
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.
Cesarean Delivery
Comparing 2 Types of Pain Relief After Cesarean Delivery: Spinal Morphine and TAP Block
Summary Brief Summary Standard care for pain relief after cesarean delivery is spinal morphine. Spinal morphine may be unsuitable for patients having general anesthetic or prior morphine-related side effects and can be less…
- Trial name
- NCT00799955
- Testing
- Ultrasound-guided TAP block
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postoperative Pain, Laparoscopic Hysterectomy for Benign Conditions
Randomized Clinical Trial: Effect of an Exercise Routine on Postoperative Shoulder Pain in Laparoscopic Hysterectomy
This is a clinical trial aimed at understanding the impact of a shoulder exercise routine on postoperative shoulder pain in patients who have undergone laparoscopic hysterectomy. Main Questions: 1.
- Trial name
- ERPOSP (NCT06195176)
- Testing
- Shoulder exercises, Hand exercises
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Anesthesia
The Efficacy of Pregabalin on the Duration of the Spinal Anesthesia and the Early Postoperative Pain After Total Knee Arthroplasty
the purpose of this study is to evaluate the effectiveness of administration of pregabalin 2 hours preoperatively on the onset and the duration of the spinal anesthesia in total knee arthroplasty and the role of pregabalin in…
- Trial name
- NCT05071118
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Postoperative Pain
Methadone Versus Placebo in Spine Fusion
What is the influence of methadone on postoperative analgesia after lumbar interbody fusion in opioid naïve patients or patients who are taking less than equivalent of 15 mg IV morphine each day? What is the incidence of opioid…
- Trial name
- NCT01125059
- Testing
- Methadone, Saline
- Where
- United States
- Sponsor
- Northwestern University
Living Kidney Donation, Preoperative Anxiety
Preoperative Psychotherapy and Its Effects on Anxiety, Hemodynamics, and Pain in Living Kidney Donors
Chronic kidney failure is a condition in which the kidneys progressively lose their ability to filter waste, maintain fluid and electrolyte balance, and support essential physiological functions.
- Conditions
- Living Kidney Donation, Preoperative Anxiety, Postoperative Pain
- Trial name
- PREPSY-KD (NCT07261917)
- Testing
- Preoperative Psychiatric Consultation, No Intervention: Standard Preoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Postoperative Pain
Postoperative Pain After the Use of Different Root Canal Sealers
This study evaluated the postoperative pain after the endodontic treatment using AH Plus, Endoseal MTA and EndoSequence BC sealers in root canal obturation.
- Trial name
- NCT03919318
- Testing
- Root Canal Filling Sealers
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Postoperative Pain, Breast Cancer
Administration of Ketamine to Prevent the Post-operative Pain
The surgery of breast cancer is responsible for post-operative pain, needing in about 30% some morphine consumption; like that, the association of ketamine with general anaesthesia may decrease morphine's use and so its adverse…
- Trial name
- KETAMINE (NCT00210210)
- Testing
- Ketamine, Saline solution
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Institut Bergonié
Postoperative Pain
To Evaluate the Safety, Tolerability and Analgesic Efficacy of SAF312 in Postoperative Dental Pain Patients
The study will assess the analgesic efficacy and safety and tolerability of a single oral dose of SAF312 in postoperative dental pain patients after 3rd molar extraction.
- Trial name
- NCT00986882
- Testing
- SAF312A, Ibuprofen
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Novartis
Infertility (IVF Patients), Infertility Treatment
Ketorolac Use and Fresh Embryo Transfer Outcomes
Ketorolac is a medication often used to relieve pain after surgery. In the past, infertility doctors have been cautious about using ketorolac after egg retrieval for patients planning a fresh embryo transfer (usually done 5 days…
- Conditions
- Infertility (IVF Patients), Infertility Treatment, Post-op Pain, Fresh Embryo Transfer
- Trial name
- NCT07185724
- Testing
- Ketorolac 30 mg IV
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Jessica D. Kresowik
Acute Pain, Burns
Oliceridine in Patients With Acute Burn Injuries
Pain after acute burn injury is complex with much still not understood. The primary mechanism is believed to be nociceptive, but is interwoven with aspects of somatogenic, neuropathic, and psychogenic pathways.
- Conditions
- Acute Pain, Burns, Adverse Drug Event, Respiratory Depression
- Trial name
- RELIEVE (NCT05465226)
- Testing
- Oliceridine, Historical opioid use
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Tennessee
Analgesia
Safety of F14 Following Total Knee Replacement
Open-label single-arm study in which all subjects receive F14 as part of a scheduled TKR and multimodal analgesia
- Trial name
- NCT04860635
- Testing
- F14 (sustained release celecoxib)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Arthritis Innovation Corporation
Cesarean Section, Postoperative Pain
TAP vs QLB in Patients After Cesarean Delivery
Comparison of two types of analgesia after cesarean section All patients will be anesthetized with spinal technique. Ultrasound-guided transversus abdominis plane or quadratus lumborum block to treat postoperative pain.
- Trial name
- NCT03404908
- Testing
- TAP (transversus abdominis plane block), QL (quadratus lumborum block), Ropivacaine
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Lublin
Relapse, Quality of Life
Ingrown Toenails : Surgery Only Versus Surgery + Chemical Cauterization With TCA
Ingrown toenail is a very common disease in the general population that touches young adults. There are lots of treatments from local care of pedicure to surgery with matricectomy.
- Conditions
- Relapse, Quality of Life, Complication, Pain, Postoperative
- Trial name
- NCT04921540
- Testing
- Ingrown toenails with surgery with chemical cauterisation, Ingrown toenails with only surgery
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Caen
Primary Osteoarthritis Requiring Total Hip Replacement
Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA)
Postoperative pain following total hip arthroplasty (THA) (1) is often considered moderate to severe and can therefore influence the postoperative course of event and result in delayed postoperative mobilization and prolonged…
- Trial name
- HÖFTPLASTIK (NCT01281891)
- Testing
- LIA, I/T morphine
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Örebro County
Inguinal Hernia Repair (Not Urgent)
Dexamethasone and Bupivacaine for Pain After Hernia Surgery
This study looked at whether a combination of two medicines, dexamethasone and bupivacaine, can reduce pain after laparoscopic hernia surgery.
- Trial name
- DEXA-BUPI (NCT07208253)
- Testing
- Bupivacaine + Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Gürkan Değirmencioğlu
Pain, Chronic, Pain, Postoperative
Evaluation of Dermatomal Distribution in the Erector Spinae Plane (ESP) Block
Interventional study that evaluate dermatomal distribution and its demographic determinants in patients who underwent to Erector Spinae Plane (ESP) block
- Trial name
- NCT03831581
- Testing
- Erector Spinae Plane Block
- Where
- Colombia
- Volunteers
- 16 people
- Sponsor
- Universidad de Antioquia