Clinical trials: Postoperative Pain Following Hysterectomy
Gynecology
the Effect of Pre-sacral Nerve Block on Post-operative Pain Following Laparoscopic Hysterectomy
40 patients who are consenting to be recruited in the study and are fulfilling the eligibility criteria will be subjected to: Group A Before the removal of uterus and the closure of vaginal cuff, insertion of 6inch 22G needle 2…
- Trial name
- NCT05757011
- Testing
- pre-sacral nerve block (bupivacaine injection into both uterosacral ligaments at the end of laparoscopic hysterectomy.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Postoperative Pain
Nurses' Negative Words and Postoperative Pain Management
Psychological implications expressed pivotal effects on daily activities. Postoperative pain management is always encountered varying influence from the ambience of surgical wards, especially the nurses.
- Trial name
- NWPOP (NCT00495807)
- Testing
- No Words, Positive words, Partially Negative Words
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Nanjing Medical University
Hysterectomy, Postoperative
A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal Hysterectomy
The main objective of this study is to demonstrate the efficacy and safety of multiple-dose application of three different oral doses of CG5503 IR (tapentadol immediate release) compared to placebo in women undergoing abdominal…
- Trial name
- NCT00478023
- Testing
- Morphine, CG5503 IR
- Where
- 52 sites in Hungary, Latvia and 7 more
- Volunteers
- 854 people
- Sponsor
- Grünenthal GmbH
Postoperative Pain Management
Vaginal Cuff Bupivacaine Injection for Postoperative Pain
This randomized controlled study evaluates whether injecting bupivacaine into the vaginal cuff during vaginal hysterectomy reduces postoperative pain. Vaginal hysterectomy is commonly performed for benign gynecologic conditions.
- Trial name
- marcaine (NCT07426666)
- Testing
- Bupivacaine %0.25 (isobaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Havva Betül Bacak
Hysterectomy, Gynecologic Surgical Procedures
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
The study is a prospective, double-blinded, placebo-controlled multi-center trial to measure if postoperative pain and the amount of narcotics used are reduced by a clinically significant amount in women undergoing minimally…
- Conditions
- Hysterectomy, Gynecologic Surgical Procedures, Narcotic Use, Pain, Postoperative
- Trial name
- ON-Q (NCT04130464)
- Testing
- Ropivacaine Infusion from ON-Q Pump, Ropivacaine + Ketorolac Infusion from ON-Q Pump, Normal Saline Infusion from ON-Q Pump
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ying Liu
Postoperative Pain, Opioid Induced Constipation
A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy
Objectives: Primary objective: To demonstrate that the treatment with OXN PR tablets up to 72 hrs after surgery is superior to the treatment with OxyPR with regards to constipation in subjects with postoperative pain after…
- Trial name
- NCT01109511
- Testing
- naloxone, oxycodone
- Where
- Norway
- Volunteers
- 85 people
- Sponsor
- Ullevaal University Hospital
Hysterectomy, Methylprednisolone
The Effect of a Preoperative Single-dose Methylprednisolone on the Postoperative Rehabilitation After Abdominal Hysterectomy
The purpose of this study is to evaluate the effect of 125 mg methylprednisolone, given intravenously 60-90 minutes before abdominal surgery,on the postoperative rehabilitation after abdominal hysterectomy.Sodium Chloride is the…
- Conditions
- Hysterectomy, Methylprednisolone, Postoperative Pain
- Trial name
- NCT01106547
- Testing
- Methylprednisolone 125mg, Sodium Chloride 2 ml
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Postoperative Pain, Chronic Postsurgical Pain
Effect of Erector Spinae Plane Block on Neuropathic Pain After Abdominal Hysterectomy
This study evaluated whether bilateral erector spinae plane block (ESPB) performed before abdominal hysterectomy could reduce postoperative pain and the development of chronic and neuropathic pain.
- Trial name
- NCT07830706
- Testing
- Bupivacaine, Standard Perioperative Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Necmettin Erbakan University
Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal
Effect of Abdominal Ice Pack After vNOTES Hysterectomy
This randomized, controlled, open-label, parallel-group clinical trial is designed to investigate the efficacy of abdominal ice pack application as an adjunct to standard pain management following vNOTES (Vaginal Natural Orifice…
- Conditions
- Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal, vNOTES, Postoperative Pain Following Hysterectomy
- Trial name
- NCT07626684
- Testing
- Abdominal Ice Pack + ERAS
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Erzincan Military Hospital
Pelvic Adhesions, Post Hysterectomy Pain
Effects of Soft Tissue Mobilization and Pelvic Floor Muscle Exercises on Pelvic Adhesions
Adhesions are permanent tissue connections that are created by fibrin deposition between different tissue planes or organs. They are a part of the internal healing process and inflammatory reactions that go through several…
- Trial name
- NCT06658210
- Testing
- soft tissue mobilization with pelvic floor muscle exercises, soft tissue mobilization without pelvic floor muscle exercises
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Chronic Postoperative Pain
Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy: Analysis of Risk Factors and Association With Genetic Polymorphisms
The treatment of postoperative pain continues to be inadequate in the investigators practice setting. Inadequate pain treatment not only contributes to postoperative complications in the short term but can also be a factor that…
- Trial name
- NCT01510496
- Testing
- Inguinal herniorraphy., Hysterectomy., Thoracotomy .
- Where
- 26 sites in Spain
- Volunteers
- 3,979 people
- Sponsor
- Fundacion IMIM
Postoperative Care, Pain Management
Effectiveness of Curcuminoids in Controlling Postoperative Pain Following Total Laparoscopic Hysterectomy
Total hysterectomy is one of the most common surgical procedures in gynecology. Total laparoscopic hysterectomy (TLH) has several advantages over open surgery, such as better cosmetic outcomes, faster recovery, and an earlier…
- Trial name
- NCT06886035
- Testing
- liposomal curcumin
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Uterine Myoma, Persistent Post-menpausal Bleeding
Intravenous or Intra-abdominal Local Anesthetics for Postoperative Pain Management.
Local anesthetics (LA) are increasingly used for postoperative pain management. Speicifically, several studies have found benefit of LA injected intra-abdominally following abdominal hysterectomy.
- Conditions
- Uterine Myoma, Persistent Post-menpausal Bleeding, Uterine Cancer
- Trial name
- PoPuLAR (NCT01492179)
- Testing
- Normal saline, Intravenous Lidocaine, Intra-abdominal Lidocaine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Örebro University, Sweden
Pain, Postoperative
PREEMPTİVE PARA-CERVİCAL BLOCK FOR POSTOPERATİVE PAIN AFTER LAPAROSCOPIC HYSTERECTOMY
Total hysterectomy is one of the most common surgical procedure in gynecology. The laparoscopic route for the performance of hysterectomies are on the rise [1].
- Trial name
- NCT05341869
- Testing
- Para-cervical block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Postoperative Pain
Clinical Analysis of Pain After Hysterectomy
Patients undergone either laparoscopic or vaginal hysterectomy will called for a clinical examination 1-3 years after surgery, if they suffer from pain 6 months after surgery. The aims of the study are: 1.
- Trial name
- NCT01706549
- Where
- Finland
- Volunteers
- 16 people
- Sponsor
- Tampere University Hospital
Intertransverse Process Block, Mtapa Block
Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Hysterectomy
This randomized clinical trial aims to evaluate and compare the analgesicefficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients…
- Conditions
- Intertransverse Process Block, Mtapa Block, Laparoscopic Hysterectomy, Postoperative Pain
- Trial name
- NCT07599787
- Testing
- Intertransverse Process Block, M-TAPA Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Post Operative Pain, Laparoscopic Hysterectomy
Preoperative Acetazolamide
The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain.
- Conditions
- Post Operative Pain, Laparoscopic Hysterectomy, Referred Pain
- Trial name
- NCT07101250
- Testing
- Acetazolamide 500 MG Extended Release Oral Capsule
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Prisma Health-Upstate
Postoperative Pain Following Total Laparoscopic Hysterectomy
COMPARISON OF THE POSTOPERATIVE ANALGESIC EFFECTS OF ULTRASOUND-GUIDED QUADRO-ILIAC PLANE AND TRANSVERSUS ABDOMINIS PLANE BLOCKS IN PATIENTS UNDERGOING TOTAL LAPAROSCOPIC HYSTERECTOMY
Postoperative pain management is an important component of recovery after total laparoscopic hysterectomy. Regional anesthesia techniques may reduce postoperative opioid consumption and improve patient comfort.
- Trial name
- QIPB-TAP-TLH (NCT07899190)
- Testing
- Ultrasound-Guided Bilateral Quadro-Iliac Plane Block, Ultrasound-Guided Bilateral Transversus Abdominis Plane Block
- Volunteers
- 60 people
- Sponsor
- Hitit University
Pain, Postoperative, Hernia, Ventral
An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries
This is a multicenter, Phase 3, open-label, safety, tolerability, and characterization of pharmacokinetics study of the INL 001 (bupivacaine HCl) implant, at 300 mg, in patients following various soft-tissue surgeries: open…
- Conditions
- Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy
- Trial name
- NCT04785638
- Testing
- INL-001 (bupivacaine hydrochloride) implant
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Innocoll
Pain, Postoperative
Ketamine Effects as Preemptive Analgesia
The goal of this randomized controlled trial is to compare the effect of preemptive ketamine administration to placebo administration in patients underwent hysterectomy surgery. The main questions it aims to answer are: 1.
- Trial name
- NCT06040060
- Testing
- Ketamine
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Padjadjaran