Clinical trials: Postoperative Pain Following Hysterectomy
Post Operative Pain
Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy
In this randomized, controlled, observer-blinded study we plan to evaluate ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management in patients undergoing abdominal hysterectomy.
- Trial name
- TAP (NCT01153503)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Pain
Predictors of Postoperative Pain
The purpose of the study is to prove that pain scores generated from painful stimuli applied preoperatively may help identify the inter-individual variability in pain perception.
- Trial name
- NCT01449318
- Testing
- Thermal Sensory Analyzer (Senselab)
- Where
- 2 sites in Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Postoperative Pain, Laparoscopic Hysterectomy
Impact of Preoperative Quadratus Lumborum Block on Postoperative Opioid Consumption After Laparoscopic Hysterectomy
The goal of this clinical trial is to learn if preoperative nerve block (quadratus lumborum [QL] block) works to improve pain control during and after laparoscopic hysterectomy.
- Conditions
- Postoperative Pain, Laparoscopic Hysterectomy, Nerve Block, Quadratus Lumborum Block
- Trial name
- NCT06709716
- Testing
- Quadratus Lumborum Block (QLB), Quadratus lumborum block, Local Anesthetic Solution
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Walter Reed National Military Medical Center
Postoperative Pain
Pain After Laparoscopic Hysterectomy
The investigators evaluated postoperative pain after total laparoscopic hysterectomy. Two arm are evaluated. During laparoscopic hysterectomy, in one arm; abdominal cavity was washed by saline at normal room temperature.
- Trial name
- NCT05784493
- Testing
- Study group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Namik Kemal University
Postoperative Pain
TAP Block With Magnesium Sulfate Added to Local Anesthetic in Abdominal Hysterectomy
Major abdominal surgeries are associated with severe abdominal pain, which can affect respiratory and cardiac functions, if insufficiently managed. This increases the incidence of post-operative morbidity.
- Trial name
- NCT02930707
- Testing
- Magnesium Sulfate, Bupivacaine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pain, Postoperative
Do Patient Educational Videos Improve Pain and Recovery After Laparoscopic Hysterectomy?
The use of multi-model patient education has been used in a variety of medical specialties to educate patients on expectations for various medical procedures and improve patients' understanding of their own health care.
- Trial name
- NCT06265376
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Pain, Postoperative
Preemptive Analgesia With Amitryptyline for Prevention of Pain in Women After Hysterectomy
The purpose of this study is to determine whether amitryptyline is effective in the prevention of pain in women after a total abdominal hysterectomy.
- Trial name
- NCT03587025
- Testing
- Amitriptyline
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Campinas, Brazil
Pain
Local Infiltration Analgesia After Abdominal Hysterectomy
The aim of the study is to evaluate traditional analgesic therapy after abdominal hysterectomy with single infiltration of local anesthetics in the surgical area at the end of surgery.
- Trial name
- LIA (NCT01782781)
- Testing
- ropivacaine, ketorelac and epinephrine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Postoperative Pain, Hysterectomy
Ibuprofen Versus Ketorolac for Perioperative Pain Control After Open Hysterectomy
The aim of this study is to compare the analgesic effect of intravenous ibuprofen to ketorolac for pain control after open hysterectomy
- Trial name
- NCT05610384
- Testing
- Ketorolac Injectable Solution, Ibuprofen 800 mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Chronic Postsurgical Pain
Vaginal or Laparoscopic Hysterectomy, Persistent Postsurgical Pain
Previous studies have shown that chronic pain after hysterectomy is common. The aim of this study is to investigate the incidence of chronic pain after vaginal or laparoscopic hysterectomy for benign reasons.
- Trial name
- NCT01537731
- Testing
- vaginal or laparoscopic hysterectomy
- Where
- Finland
- Volunteers
- 225 people
- Sponsor
- Tampere University Hospital
Post Operative Pain
Preemptive Acetaminophen for Postoperative Pain Control Following Minimally Invasive Hysterectomy
This study is investigating whether administration of acetaminophen the day before surgery improves post operative pain following minimally invasive hysterectomy.
- Trial name
- NCT04360135
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Postoperative Pain
Transversus Abdominis Plane Block Versus Ilioinguinal-Iliohypogastric Nerve Block for Postoperative Analgesia Following Open Total Abdominal Hysterectomy
The investigators hypothesised that ultrasound-guided transversus abdominis plane (TAP) block would prolong the time to first rescue nalbuphine within 24 hours compared with ultrasound-guided ilioinguinal-iliohypogastric (IIH)…
- Trial name
- NCT05656872
- Testing
- Transverse Abdominis Plane Block, Ilioinguinal-iliohypogastric block
- Where
- 2 sites in Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Hysterectomy, Chronic Pain
Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy
Phase 1 (started in July 2019): Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP), but a complete…
- Conditions
- Hysterectomy, Chronic Pain, Central Sensitisation, Anxiety Depression
- Trial name
- EPOCH (NCT04014829)
- Testing
- Pain-Pressure Threshold, Mechanical Temporal Summation, Hospital Anxiety and Depression Scale
- Where
- Singapore
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Leiomyoma, Pelvic Organ Prolapse
The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures
This study evaluates the influence of the transversus abdominis plane block on the intensity of postoperative pain and the concentration of proinflammatory and pain factors after hysterectomy by laparotomy.
- Conditions
- Leiomyoma, Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Chronic Pain
- Trial name
- TAP (NCT04172272)
- Testing
- Systemic multimodal analgesia administered intravenously, Transversus abdominis plane block (TAP block), Combined transversus abdominis plane block (TAP block) with systemic multimodal analgesia administered intravenously
- Where
- 2 sites in Croatia
- Volunteers
- 75 people
- Sponsor
- General Hospital Pula
Pelvic Organ Prolapse
Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hysterectomy and Pelvic Reconstructive Surgery
This study will investigate pain outcomes for patients undergoing vaginal hysterectomy with pelvic reconstructive surgery using the LigasureTM vessel sealing device as compared to conventional clamping and suturing methods.
- Trial name
- NCT05192954
- Testing
- LigaSureTM vessel sealing device
- Where
- 2 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Marlana McDowell
Laparoscopic Hysterectomy, Postoperative Recovery
Perioperative Duloxetine for Pain Management After Laparoscopic Hysterectomy
The aim of the investigators of the study is to evaluate the effect of peri-operative duloxetine on post-operative recovery in patients undergoing laparoscopic hysterectomy.
- Conditions
- Laparoscopic Hysterectomy, Postoperative Recovery, Postoperative Pain
- Trial name
- NCT03350334
- Testing
- Duloxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Post-Op Complication
Effect of Early Rehabilitation on Recovery Following Abdominal Hysterectomy
Variety of physical therapy treatments have been used after open abdominal surgery to improve cardiopulmonary and physical function as well as to reduce the incidence of postoperative pulmonary complications.
- Trial name
- NCT04686032
- Testing
- Advanced early Rehabilitation Program, Early ambulation
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Postoperative Pain, Post Operative Analgesia
Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy
Dexamethasone has been recognized as an antiemetic agent after surgeries, and the combination of dexamethasone and tramadol remained stable in solution up to 5 days. In addition, i.v.
- Conditions
- Postoperative Pain, Post Operative Analgesia, Patient-Controlled Analgesia, Abdominal Surgeries
- Trial name
- DTMPCA (NCT00564603)
- Testing
- Dexamethasone Sodium Phosphate Injection, 0.9% Saline
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Nanjing Medical University
Pain, Postoperative, Hysterectomy
Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy
The purpose of this study is to evaluate the effect of using ice packs on the abdomen immediately after laparoscopic hysterectomy surgery on pain control and narcotic pain medication use.
- Conditions
- Pain, Postoperative, Hysterectomy, Narcotic Use, Cryotherapy Effect
- Trial name
- NCT03341533
- Testing
- Ice packs plus usual post-op analgesia, Usual post-op analgesia
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Mayo Clinic
Postoperative Pain
The Impact of Chewing Gum on Postoperative Bowel Activity and Postoperative Pain After Total Laparoscopic Hysterectomy
Surgical interventions, such as restoring the health of patients and eliminating their existing symptoms, the surgical process can have many negative effects on the patient.
- Trial name
- NCT05135416
- Testing
- chewing gum Group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital