Clinical trials: Postoperative Pain Management, After VATS
Pain, Postoperative, Thoracic Diseases
Liposomal Bupivacaine for Pain Control Following Thoracic Surgery.
The aims of the study are to compare the effectiveness and postoperative outcomes of liposomal bupivacaine vs plain bupivacaine following video-assisted thoracoscopic surgery.
- Conditions
- Pain, Postoperative, Thoracic Diseases, Local Anesthetics Causing Adverse Effects in Therapeutic Use, Opioid Dependence
- Trial name
- NCT03036085
- Testing
- Liposomal bupivacaine, Bupivacaine, Epinephrine
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Postoperative Pain, Lung Cancer
Postoperative Pain Management on Patients Undergoing Lung Tumor Resection
Multimodal analgesia (MMA) is an essential part of Enhanced Recovery After Surgery (ERAS) protocol. The principle of MMA is to manage pain with analgesics of multiple classes acting on distinct target sites through different…
- Conditions
- Postoperative Pain, Lung Cancer, Lung Tumor
- Trial name
- NCT06397807
- Testing
- Dinalbuphine sebacate, Analgesic injectables, Enteral analgesics
- Volunteers
- 400 people
- Sponsor
- China Medical University Hospital
Post Operative Pain, Thoracic Cancer
Thoracic Paravertebral Block With Methylene Blue Visual Confirmation for Postoperative Pain After VATS Lobectomy
The goal of this study is to compare the efficacy in controlling postoperative pain of paravertebral block (PVB) with methylene blue visual confirmation and thoracic epidural anesthesia (TEA).
- Trial name
- NCT05812521
- Testing
- Paravertebral block with methylene blue, Thoracic Epidural Anesthesia
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Campania Luigi Vanvitelli
Thoracic Surgery, Video-Assisted
Erector Spinae Plane Block For Analgesia Following Video-Assisted Thoracoscopic Surgery
Erector spinae (ESP) block is a recently described plane block designed to block the dorsal and ventral rami of the thoracic spinal nerves. It is meant to block the ipsilateral trunk.
- Trial name
- NCT03860480
- Testing
- ESP with Bupivacaine 0.5%, ESP with Saline 0.9%
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Lung Cancer, Pain
Two-Point Versus Single-Point Serratus Anterior Plane Block for Post-Thoracoscopic Surgery Analgesia
Postoperative pain remains a common clinical challenge in patients undergoing video-assisted thoracoscopic surgery (VATS), impairing early recovery and increasing opioid consumption.
- Conditions
- Lung Cancer, Pain, Video-Assisted Thoracoscopic Surgery, Serratus Anterior Plane Block
- Trial name
- NCT07700823
- Testing
- Two-Point Serratus Anterior Plane Block, Single-Point Serratus Anterior Plane Block
- Volunteers
- 88 people
- Sponsor
- Shiyou Wei
Thoracic, Pain, Postoperative
Intercostal Nerve Block for Pain Management After Uniportal Video-assisted Thoracoscopic Surgeries
The goal of this clinical trial is to compare the safety and effectiveness of the three intercostal nerve blocks used in pain management in uniportal (one port) thoracoscopic surgeries: internal intercostal nerve blocks (ICNB)…
- Conditions
- Thoracic, Pain, Postoperative, Analgesia, Satisfaction, Patient
- Trial name
- VATS (NCT06838026)
- Testing
- External Intercostal Nerve Block, Internal Intercostal Nerve Block, Intercostal Catheter
- Where
- 2 sites in Palestinian Territories
- Volunteers
- 90 people
- Sponsor
- Al-Quds University
Postoperative Pain Management
Ultrasound-Guided Erector Spinae Plane Block Versus Intravenous Nalbuphine
2.1. Study population and setting: This prospective, randomized, controlled clinical trial will be conducted at the thoracic surgery operation room, cardiothoracic surgery building, Zagazig University Hospitals, from July 2025 to…
- Trial name
- VATS (NCT07391475)
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Zagazig University
Post-operative Pain, Acute, Post-operative Pain
Postoperative Analgesia y After Uniportal Video-assisted Thoracoscopic Surgery
Ultrasound-guided erector spinae plane block (ESPB) is an interfascial blockade during thoracic anesthesia, first described by Forero in 2016, and is highlighted by technically feasibility and less complication rate.
- Conditions
- Post-operative Pain, Acute, Post-operative Pain, Thoracic Diseases, Post-Op Complication
- Trial name
- NCT05242328
- Testing
- Ultrasound-guided erector spinae plane block, surgical thoracoscopic intercostal nerve block
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Postoperative Pain, Thoracic Surgery, Video Assisted
Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
This prospective randomized controlled trial was conducted to compare the effectiveness of two ultrasound-guided regional anesthesia techniques, erector spinae plane block (ESPB) and serratus posterior superior intercostal plane…
- Trial name
- NCT07426692
- Testing
- Erector Spinae Plane Block (ESPB) group, Serratus posterior superior intercostal plane block, Morfin
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Marmara University
Postoperative Pain, Thoracic Surgery
Intravenous Lidocaine, Ketamine, and Magnesium in Thoracic Surgery
Thoracic surgery often produces severe postoperative pain due to nerve injury and inflammation. Effective pain control is essential to reduce complications and opioid use.
- Conditions
- Postoperative Pain, Thoracic Surgery, Multimodal Analgesia, Opioid Consumption, Postoperative
- Trial name
- LKM-Thorax (NCT07359469)
- Where
- Spain
- Volunteers
- 118 people
- Sponsor
- Universidad Pública de Navarra
Post Operative Pain, Opioid Use
Ultrasound-guided Erector Spinae Plane Block Using Catheter for Video-assisted Thoracoscopy
Different modalities ranging from patient controlled analgesia (PCA) to different regional blocks have been used to control postoperative pain after thoracic surgeries.
- Trial name
- NCT05337956
- Testing
- Erector spinae plane block catheter
- Where
- Saudi Arabia
- Volunteers
- 34 people
- Sponsor
- Security Forces Hospital
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
Chronic Postsurgical Pain
Effect of Oliceridine Patient-Controlled Intravenous Analgesia on Postoperative Chronic Pain After Video-Assisted Thoracoscopic Lung Resection
The primary objective is to evaluate the impact of oliceridine versus sufentanil for perioperative analgesia on the incidence of chronic postsurgical pain (CPSP) with functional impact in patients undergoing video-assisted…
- Trial name
- NCT07018375
- Testing
- Oliceridine, Sufentanil
- Where
- 7 sites in China
- Volunteers
- 320 people
- Sponsor
- Tianjin Medical University General Hospital
Pain Management
Intrapleural Bupivacaine Analgesia for Postoperative Pain Management After Minimally Invasive Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
Postoperative pain is common after video-assisted thoracoscopic surgery (VATS), with pleural irritation caused by chest tube placement being a major contributor.
- Trial name
- IBVATS (NCT07393386)
- Testing
- Bupivacaine 0.125%, Bupivacaine 0.25%, Normal Saline
- Where
- China
- Volunteers
- 249 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Lung Diseases
Rhomboid Intercostal Block for Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Analgesia management is very important for these patients in postoperative period since insufficient…
- Trial name
- NCT04428216
- Testing
- Group RIB
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Anesthesia Recovery Period, Pain, Postoperative
Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery
The main hypothesis of this study is that preoperative administration of controlled-release (CR) oxycodone may reduce acute postoperative pain and improve time to discharge from the post-anesthesia care unit in patients…
- Trial name
- NCT00681174
- Testing
- Morphine, oxycodone, Paravertebral block
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- University of Parma
Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS)
Analgesic Effectiveness of SPSIPB Versus Thoracic Epidural and Systemic Opioid Analgesia After VATS (SPSIPB-VATS)
This prospective observational study aims to compare the postoperative analgesic effectiveness of three commonly used pain management strategies in video-assisted thoracoscopic surgery (VATS): Serratus Posterior Superior…
- Conditions
- Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS), Thoracic Epidural Analgesia, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- SPSIPB-VATS (NCT07238348)
- Volunteers
- 120 people
- Sponsor
- Karadeniz Technical University
Post Operative Pain
Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy
The project is of a comparative nature. It seeks to study pain reduction following two forms of chest surgery and compare results between both procedures. It will use kinesio taping as the studied pain reducer.
- Trial name
- NCT05200689
- Testing
- Kinesiotaping (KT)
- Where
- 5 sites in Egypt, Italy and 2 more
- Volunteers
- 310 people
- Sponsor
- Al-Quds University
Lung Diseases
Erector Spinae Plane Block or Serratus Anterior Plane (SAP) Block Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960762
- Testing
- ESP block (Group ESP), SAP block (Group SAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Pain, Postoperative
Thoracic Paravertebral Block for Postoperative Analgesia After Video-assisted Thoracic Surgery.
The use of paravertebral catheters is a recommended technique to achieve postoperative analgesia after thoracic surgery. To date there is no consensus on which drug regime (local anesthetics with or without opioid) is best.
- Trial name
- PARAVI (NCT01082744)
- Testing
- Ropivacaine + Sufentanil, Ropivacaine
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon