Clinical trials: Postoperative Pulmonary Complication
Complication of Surgical Procedure, Acute Respiratory Failure, Adult
Prospective Evaluation of a RIsk Score for Postoperative Pulmonary COmPlications in Europe
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric…
- Conditions
- Complication of Surgical Procedure, Acute Respiratory Failure, Adult, Postoperative Respiratory Complications, Pulmonary Failure
- Trial name
- PERISCOPE (NCT01346709)
- Where
- 63 sites in Albania, Belgium and 19 more
- Volunteers
- 5,450 people
- Sponsor
- European Society of Anaesthesiology
CABG, Valve Surgery
Effects of Deep Breathing Exercises Two Months After Cardiac Surgery
Hypothesis: Deep breathing exercises performed during the first two months after cardiac surgery, will improve pulmonary function and patient-perceived quality of recovery.
- Trial name
- NCT01282671
- Testing
- Breathing exercises
- Where
- 2 sites in Sweden
- Volunteers
- 357 people
- Sponsor
- Uppsala University
Heart Diseases, Heart Valve Diseases
To Investigate the Effect of Esketamine Hydrochloride on Pulmonary Complications
The objective of this study was to evaluate the effect of esketamine on intraoperative hemodynamics in patients with heart valve replacement and to mitigate postoperative pulmonary complications
- Trial name
- NCT06467513
- Testing
- Esketamine hydrochloride injection
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Zhang XIao Mei
Postoperative Atelectasis, Bariatric Surgery Candidate
Can the Effects of High Flow Nasal Cannula Oxygenation on Postoperative Atelectasis be Evaluated With Lung Ultrasound
Evaluate the effects of high-flow nasal oxygen therapy on atelectasis in the perioperative period by lung ultrasound (LUS) in bariatric surgery patients.
- Conditions
- Postoperative Atelectasis, Bariatric Surgery Candidate, Ultrasound Therapy; Complications
- Trial name
- NCT03828513
- Testing
- High flow nasal cannula oxygen is applied, High flow nasal cannula oxygen is not applied
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Tracheostomy Complication, Inflammation
Postoperative Inflammation and Recovery After Tracheostomy
The main purpose of this study is to examine if there are differences in postoperative inflammation following percutaneous dilatation tracheostomy versus surgical tracheostomy in intensive care unit patients.
- Conditions
- Tracheostomy Complication, Inflammation, Post-operative Complications
- Trial name
- NCT02096640
- Testing
- Type of surgical teqnique for tracheostomy
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Sormland County Council, Sweden
Postoperative Complications, Abdominal Surgery
Intraoperative Lung Protective Ventilation Needs Periodic Lung Recruitment Maneuvers
Postoperative Pulmonary Complications (PPC) are common. It severely affects postoperative recovery, particularly in abdominal surgery.
- Conditions
- Postoperative Complications, Abdominal Surgery, Intraoperative Mechanical Ventilation
- Trial name
- REMAIN-1 (NCT05556174)
- Testing
- periodic lung recruitment maneuvers
- Where
- China
- Volunteers
- 1,060 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Postoperative Complications, Surgical Site Infection
Hierarchy of Effects of Laboratory Markers and Their Interaction With Comorbidity Concerning Outcome and Personalized Treatment of Trauma Patients in Emergency Care and Rehabilitation
At least ten percent of trauma patients suffer from any sort of complication. The study aims to identify a risk factor profile to early identify trauma patients at risk.
- Conditions
- Postoperative Complications, Surgical Site Infection, Wound Infection, Non-healing Wound
- Trial name
- HELICOPTER (NCT06758427)
- Where
- Germany
- Volunteers
- 2,300 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Lung Transplant; Complications, Extracorporeal Circulation; Complications
Routine Versus Selective Intraoperative ECMO in Lung Transplant
Intraoperative hemodynamic management is vital in the success of lung transplantation. Significant intraoperative hemodynamic compromise and hypoxic episodes may contribute to an increase in severe postoperative complications…
- Conditions
- Lung Transplant; Complications, Extracorporeal Circulation; Complications, Postoperative Complications
- Trial name
- NCT05505422
- Testing
- Routine ECMO, On demand ECMO
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Surgical Procedure, Unspecified
Lung Expansion Technics on Chest Wall Mechanics and Preventing Pulmonary Complication After Abdominal Surgery
The lung expansion techniques are widely used to prevent postoperative pulmonary complications. However, the effect of each technique on thoracoabdominal mechanics after abdominal surgery and if it influences the rate of…
- Trial name
- NCT01993602
- Testing
- Breathing exercises
- Where
- Brazil
- Volunteers
- 171 people
- Sponsor
- University of Sao Paulo General Hospital
Lung Cancer, Post-Op Complication
Pre-habilitation in Lung Surgery Candidates
We hypothesize that high intensity respiratory muscle training will improve ventilatory efficiency (VE/VCO2 slope) and will be associated with decreased PPC, decreased mortality and better quality of life in lung resection…
- Trial name
- NCT04826575
- Testing
- High intensity inspiratory and expiratory muscle training
- Where
- 3 sites in Czechia
- Volunteers
- 150 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Primary Graft Dysfunction, Lung Transplantation
Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation
Primary graft dysfunction (PGD) is a severe lung injury that can occur in the days following lung transplant surgery. The purpose of this study is to identify genetic factors that may put someone at risk for developing PGD.
- Trial name
- NCT00457847
- Where
- United States
- Volunteers
- 1,150 people
- Sponsor
- University of Pennsylvania
Hypoxemia, Hypercapnia
Optimising Ventilatory Strategies by Using Positive Respiratory Integer Measurements
Background Intermittent Positive Pressure Ventilation is used during general anesthesia but can lead to serious complications. Respiratory parameter settings can be adjusted to minimize the detrimental effects of this…
- Conditions
- Hypoxemia, Hypercapnia, Ventilator Associated Pneumonia, Complication of Anesthesia
- Trial name
- OPTIMVSPRIME (NCT06298435)
- Testing
- Intermittent Positive pressure ventilation
- Where
- Netherlands
- Volunteers
- 20,000 people
- Sponsor
- University Medical Center Groningen
Postoperative Complications After Lung Transplantation
The Effect of Perioperative Factors on Postoperative Outcomes After Lung Transplantation
1. Evaluate the influence of perioperative factors on postoperative outcomes in patients undergoing lung transplantation patients. 2.
- Trial name
- NCT06603350
- Testing
- No intenvention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Atelectasis, Postoperative Pulmonary Atelectasis
Lung Ultrasound Assessment of Postoperative Atelectasis After Mechanical Ventilation With Minimum Driving Pressure
Brief summary The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure…
- Conditions
- Postoperative Atelectasis, Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications (PPCs), Lung Ultrasonography Score
- Trial name
- NCT07186920
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Lung Cancer, Surgery
Effects of Inspiratory Muscle Training After Lung Cancer Surgery, a Randomized Controlled Trial
The purpose of this study is to evaluate the effects of postoperative inspiratory muscle training on the recovery of respiratory muscle strength in high risk patients referred for lung cancer surgery.
- Trial name
- NCT01793155
- Testing
- Inspiratory muscle training
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aalborg University Hospital
Mechanical Ventilation Complication, Intensive Care Unit
INTELLiVENT-ASV Using Mainstream Versus Sidestream End-Tidal CO2 Monitoring
Background INTELLiVENT-ASV, an automated closed-loop mode of mechanical ventilation, available on Hamilton ventilators for clinical use, uses mainstream end-tidal CO2 (etCO2) monitoring to adjust minute ventilation.
- Conditions
- Mechanical Ventilation Complication, Intensive Care Unit, Postoperative Care
- Trial name
- INTELLiSTREAM (NCT04599491)
- Testing
- Sidestream capnography using the 'Respironics LoFlo Sidestream CO2 Module', Mainstream capnography using the 'Respironics Capnostat 5 Mainstream CO2 sensor'
- Where
- Netherlands
- Volunteers
- 72 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Lidocaine, Analgesia
Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection
The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection.
- Conditions
- Lidocaine, Analgesia, Pain, Postoperative, Thoracic Surgery
- Trial name
- NCT05901389
- Testing
- Lidocaine, Sufentanil
- Where
- China
- Volunteers
- 451 people
- Sponsor
- Qilu Hospital of Shandong University
Postoperative Pulmonary Complications
Respiratory Variability for Respiratory Monitoring During the Postoperative Recovery Period
The research consist of measuring respiratory variability of several variables of the respiratory pattern at rest and during exercise using a thoracic movement measuring technique.
- Trial name
- VariaRessPi (NCT04605250)
- Testing
- Respiratory variability before and after surgery
- Where
- Martinique
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Mechanical Ventilation Complication, Postoperative Pulmonary Atelectasis
Flow Controlled Ventilation in Robot-assisted Laparoscopic Surgery
The optimization of ventilation is especially important during general anaesthesia, when active, physiologic respiration suspends and is replaced by non-physiologic mechanical positive pressure ventilation.
- Trial name
- FCV-IMPALA (NCT06256900)
- Testing
- Flow-controlled ventilation, Pressure-controlled ventilation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Lung Cancer, Surgery--Complications
Assessment of the 90-day Mortality Risk Score After VATS Lobectomy
A five classes (A-E) aggregate risk score predicting 90-day mortality after video-assisted thoracoscopic lobectomy for lung cancer, including as independent factors male sex (3 points), carbon monoxide lung diffusion capacity…
- Conditions
- Lung Cancer, Surgery--Complications, Morality
- Trial name
- NCT04799509
- Testing
- VATS lobectomy
- Volunteers
- 2,209 people
- Sponsor
- Università degli Studi dell'Insubria