Clinical trials: Postoperative Pulmonary Complication
Segmentectomy
Comparison of Energy Instruments and Stapling Device to Dissect Intersegmental Plane in Segmentectomy
According to published studies, there are two main approaches in the dissection of intersegmental plane: stapling devices and energy instrument separation.
- Trial name
- NCT03192904
- Testing
- Energy Instruments, Stapling Device
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Ruijin Hospital
Prolonged Air Leak, Post-operative Pain
Phrenic Nerve Infiltration: Pulmonary Expansion and Pain Control
Between January 2021-2023, 65 consecutive patients at risk for PAL (defined in accordance to "2019 Society of Thoracic Surgery score-criteria of PAL") underwent lung resection (lobectomy or sublobar resection) for malignancy.
- Trial name
- NCT06356038
- Testing
- intra-operative phrenic nerve infiltration
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Azienda Ospedaliera "Sant'Andrea"
Postoperative Pulmonary Complications
Using Thoracic Paravertebral Block for Perioperative Lung Preservation During VATS Pulmonary Surgery
Background: Postoperative pulmonary complications (PPCs) may extend the length of stay of patients and even increase perioperative mortality after video-assisted thoracoscopic (VATS) pulmonary surgery.
- Trial name
- NCT05922449
- Testing
- Thoracic Paravertebral Block
- Where
- 2 sites in China
- Volunteers
- 302 people
- Sponsor
- Beijing Tongren Hospital
Non-Small Cell Lung Cancer
20-Fr Versus 24-Fr Chest Drains After Uniportal VATS Lobectomy for NSCLC
This randomized clinical trial compared two different chest drain sizes, 20 Fr and 24 Fr, in patients undergoing lung lobectomy for lung cancer.
- Trial name
- DRAIN2024 (NCT07827885)
- Testing
- 20-Fr Thoracic Drain, 24-Fr Thoracic Drain
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Lung Transplant
Intraoperative Versus Postoperative Thymoglobulin in Lung Transplantation
The purpose of this study is to take a population of lung transplant recipients who meet UCLA criteria for induction chemotherapy with thymoglobulin and prospectively study weather giving the first dose intraoperatively versus…
- Trial name
- NCT00592306
- Testing
- thymoglobulin (intraoperative), thymoglobulin (postoperative)
- Where
- United States
- Sponsor
- University of California, Los Angeles
Hypoxic-Ischemic Encephalopathy, Bronchopulmonary Dysplasia
Efficacy Evaluation of UCB-MNCs in the Treatment of Refractory Neonatal Diseases
Hypoxic-ischemic encephalopathy (HIE), bronchopulmonary dysplasia (BPD), short bowel syndrome (SBS) are refractory in clinical treatment.
- Conditions
- Hypoxic-Ischemic Encephalopathy, Bronchopulmonary Dysplasia, Short Bowel Syndrome
- Trial name
- NCT06427642
- Testing
- Mononuclear cells, Mild hypothermia therapy, Breathing support technique
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shandong Qilu Stem Cells Engineering Co., Ltd.
Pulmonary Dysfunction, Median Sternotomy Recovery
FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy
Background and Rationale: Open-heart surgery via a median sternotomy is associated with severe acute postoperative pain. This pain can impair a patient's ability to take deep breaths and cough effectively which increases the risk…
- Conditions
- Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
- Trial name
- FROST-STERN (NCT07637370)
- Testing
- Intercostal Nerve Cryoablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Postoperative Complications
Use of Disposable Spirometer for Recovery of Pulmonary Function
We hypothesize that the addition of modified incentive spirometry to standard postoperative chest physiotherapy will be associated with faster return to baseline/predicted pulmonary function and fewer postoperative pulmonary…
- Trial name
- NCT01789177
- Testing
- Incentive Spirometry, Postoperative chest physiotherapy
- Where
- Malawi
- Volunteers
- 150 people
- Sponsor
- University of North Carolina, Chapel Hill
Postoperative Pulmonary Complications
Different Algorithm Models to Predict Postoperative Pulmonary Complications in Elderly Patients
Although a number of clinical predictive models were developed to predict postoperative pulmonary complications, few predictive models have been used in elderly patients.
- Trial name
- NCT05671939
- Volunteers
- 10,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Incentive Spirometry, Postoperative Pulmonary Complication
Effectivity of Incentive Spirometry on Postoperative Pulmonary Complication After Major Abdominal Surgery
This study is the first clinical trial study in Indonesia to assess the benefits of using incentive spirometry in the incidence of pulmonary complications after major abdominal surgery.
- Conditions
- Incentive Spirometry, Postoperative Pulmonary Complication, Major Abdominal Surgery
- Trial name
- NCT05795608
- Testing
- respiratory exercise with incentive spirometry
- Volunteers
- 46 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Neuromuscular Blockade
Neuromuscular Blockade Improves Surgical Conditions
This study is designed to test the clinical hypothesis that a neuromuscular block improves surgical conditions, operation time, and post-operative pain.
- Trial name
- NISCO (NCT00895778)
- Testing
- Neuromuscular blockade with rocuronium and reversal with sugammadex
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Technical University of Munich
C.Surgical Procedure; Cardiac, Right-Sided Heart Failure
Evaluation of Monitoring TECHNOlogies in the PERI-OPerative Care of Cardiac Surgical Patients
The purpose of this prospective observational cohort study is to evaluate multimodal monitoring technologies in the perioperative care of cardiac surgical patients.
- Conditions
- C.Surgical Procedure; Cardiac, Right-Sided Heart Failure, Acute Kidney Injury, Respiratory Insufficiency
- Trial name
- TechnoPeriOp (NCT02658006)
- Testing
- Cardiac surgery
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Montreal Heart Institute
Lung Cancer, Pulmonary Complications
Study of CPAP as Intervention After Lung Resection
The aim of this study was to compare the oxygenation index (OI), dyspnea, and pain scale and evaluate the duration of thoracic drainage and pleural air leaks after lung resection in two groups of patients: chest physiotherapy…
- Trial name
- CPAP (NCT01285648)
- Testing
- Cpap
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Campinas, Brazil
Neuromuscular Block, Residual
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are…
- Trial name
- NCT05724550
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Lung Transplantation
Prediction Model for PPCs in Patients Undergoing Lung Transplantation Using Machine Learning
Since the first human lung transplantation in 1963, significant advancements in immunosuppressive agents from the mid-1990s have greatly improved the quantity and quality of such procedures.
- Trial name
- NCT06218758
- Testing
- General anesthesia
- Where
- South Korea
- Volunteers
- 214 people
- Sponsor
- Pusan National University Yangsan Hospital
COPD, Malignant Neoplasm of Thorax
Evaluation of Post-operative Respiratory Complications After Thoracic Surgery in Patients With COPD
Evaluation of post-operative respiratory complications after thoracic surgery for pulmonary resection in patients with COPD Introduction: Postoperative pulmonary complications following pulmonary resection occur in 12-40% of…
- Trial name
- NCT02268708
- Testing
- Oncological pulmonary resection
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hôpital Cochin
Coronary Heart Disease, Anemia
The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.
Study is conducted to assess the prevalence and structure of comorbidity among patients undergoing abdominal surgery and produce the stratification of the risk of postoperative complications by identifying independent predictors…
- Conditions
- Coronary Heart Disease, Anemia, Bronchial Asthma, Stroke
- Trial name
- STOPRISK (NCT03945968)
- Where
- 38 sites in Russia
- Volunteers
- 16,000 people
- Sponsor
- Russian Federation of Anesthesiologists and Reanimatologists
Carcinoma, Non-Small-Cell Lung, Pain, Postoperative
Why in Hospital After VATS Lobectomy
The study aims to identify specific or potential reasons that prolong the length of hospital stay after video-assisted thoracoscopic surgery lobectomy.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Pain, Postoperative, Postoperative Nausea and Vomiting, Infection
- Trial name
- NCT04294108
- Testing
- Prolong in-hospital stay
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Pain, Postherniotomy Pain
Neurophysiological Characterization of Postherniotomy Pain
Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome.
- Conditions
- Postoperative Pain, Postherniotomy Pain, Neuropathic Pain
- Trial name
- NCT00719368
- Where
- 2 sites in Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre