Clinical trials: Postoperative Pulmonary Complication
Positive End Expiratory Pressure, Lung Ultrasound
Comparison of PEEP Effect on Perioperative Oxygenation and Postoperative Pulmonary Complications in Lithotomy Position
The main purpose of the study is to compare the effectiveness of PEEP application in terms of perioperative oxygenation level in the use of classical LMA and i-gel, which is often preferred.
- Trial name
- NCT05261295
- Testing
- PEEP, ZEEP
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete
Reperfusion Injury
Pulmonary Protection of Transcutaneous Electrical Acupoint Stimulation in Gynecologic Laparoscopic Surgery
TEAS might protect against postoperative pulmonary such as ischemia-reperfusion injury (IRI) and atelectasis. We tested the hypothesis that transcutaneous electrical acupoint stimulation protects against postoperative pulmonary…
- Trial name
- NCT02850471
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Postoperative Pain, Thoracic Surgery
Intravenous Lidocaine, Ketamine, and Magnesium in Thoracic Surgery
Thoracic surgery often produces severe postoperative pain due to nerve injury and inflammation. Effective pain control is essential to reduce complications and opioid use.
- Conditions
- Postoperative Pain, Thoracic Surgery, Multimodal Analgesia, Opioid Consumption, Postoperative
- Trial name
- LKM-Thorax (NCT07359469)
- Where
- Spain
- Volunteers
- 118 people
- Sponsor
- Universidad Pública de Navarra
Pneumothorax, Cardiac Surgery
Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery
What is the purpose of this study? This study is being done to find out if medical trainees (such as residents and fellows) can learn to use lung ultrasound to detect a collapsed lung (pneumothorax) after heart surgery.
- Conditions
- Pneumothorax, Cardiac Surgery, Lung Ultrasound, Chest Tube Removal
- Trial name
- CLEARVGRD (NCT07018856)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Jacobo Moreno Garijo
General Anesthesia, COVID-19
Postoperative Sugammadex After COVID-19
Researcher want to compare and evaluate the effect of sugammadex on postoperative recovery, with a focus on the occurrence of postoperative urinary dysfunction, in patients who have undergone regular abdominal surgery within a…
- Trial name
- NCT05817019
- Testing
- Sugammadex Sodium, neostigmine 50µg/kg + glycopyrollate 0.01mg/kg
- Volunteers
- 300 people
- Sponsor
- Korea University Ansan Hospital
Pulmonary Complication, Post Operative Complication
Lung Ultrasound Score as Post Operative Predictive Value of Pulmonary Complications in Living Liver Transplant Recipient
The aim of this study is to determine if lung ultrasound score has a strong predictive value for post operative pulmonary complications in living liver transplant recipient
- Trial name
- NCT06498895
- Testing
- lung ultrasound
- Volunteers
- 25 people
- Sponsor
- Ain Shams University
Robotic Surgery, Post Operative Pulmonary Complications
Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study
The aim of the study is to assess whether a bundle of protective low-intensity mechanical ventilation interventions reduces perioperative atelectasis and postoperative pulmonary complications, compared with standard care in a…
- Trial name
- VIOLET (NCT07277244)
- Testing
- Low Intensity Mechanical Ventilation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Beth Israel Deaconess Medical Center
Intestines Cancer, Pulmonary Cancer
A Retrospective Cohort Study for Main Postoperative Complications After SARS-CoV-2 Infection
To explore the relationship between SARS-CoV-2 infection in different time before operation and postoperative main complications (mortality, main pulmonary and cardiovascular complications) 30 days after operation; To determine…
- Conditions
- Intestines Cancer, Pulmonary Cancer, Liver Cancer, Trauma
- Trial name
- NCT05781581
- Testing
- no intervention
- Volunteers
- 50,000 people
- Sponsor
- RenJi Hospital
Postoperative Pulmonary Complications, Impaired Oxygenation
PEEP Strategies and Mechanical Power in Robotic Surgery
Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications.
- Conditions
- Postoperative Pulmonary Complications, Impaired Oxygenation, Mechanical Ventilation
- Trial name
- NCT07536464
- Testing
- Fixed PEEP Ventilation, Decremental PEEP Strategy, Incremental PEEP Strategy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Adult, Guideline Adherence
Adherence to LPV in SICU and Associated Clinical Outcomes
Lung Protective Ventilation strategy (LPV) with low tidal volume and adequate positive end-expiratory pressure is recommended for not only patients with acute respiratory distress syndrome (ARDS) but also those without ARDS too.
- Conditions
- Adult, Guideline Adherence, Humans, Intensive Care Units
- Trial name
- NCT03698799
- Where
- Thailand
- Volunteers
- 306 people
- Sponsor
- Mahidol University
Postoperative Pain, Postoperative Complications
Protocol for Accelerated Recovery in Patients Undergoing Thoracic Surgical Procedures (PROSM). Study Randomized Comparative Between the Adoption of the Proposed Guidelines and the Traditional Method Currently Used in the Institution
Introduction: Aiming at reducing costs and optimizing the use of these financial resources, several postoperative recovery protocols have emerged that aim to reduce the length of hospital stay by accelerating surgical…
- Conditions
- Postoperative Pain, Postoperative Complications, Postoperative Nausea, Lung Cancer
- Trial name
- PROSM (NCT03271749)
- Testing
- PROSM guidelines for preoperative, anesthesia and postoperative care for lung resections
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Igor Renato Louro Bruno de Abreu
Robotic Surgery, Mechanical Ventilation
Assessment of Ventilatory Management During General Anesthesia for Robotic Surgery
The aim of this study is to assess the incidence of postoperative pulmonary complications in patients undergoing mechanical ventilation during general anesthesia for robotic surgery, to characterize current practices of…
- Trial name
- AVATaR (NCT02989415)
- Testing
- Mechanical Ventilation
- Where
- 12 sites in United States, Belgium and 4 more
- Volunteers
- 1,015 people
- Sponsor
- Hospital Israelita Albert Einstein
Thoracic Surgery
The Effect of Permissive Hypercapnia on Oxygenation and Post-operative Pulmonary Complication During One-lung Ventilation
Permissive hypercapnia increased the survival rate in patients with acute respiratory distress syndrome (ARDS) who required mechanical ventilation in critical care medicine.
- Trial name
- NCT04175379
- Testing
- group 40, group 50, group 60
- Where
- South Korea
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Artificial Intelligence (AI)
Effectiveness of Artificial Intelligence Algorithms
Introduction Throughout human history, surgical interventions have been frequently used in human treatment. However, despite their therapeutic properties, the pain experienced by patients, especially in the acute postoperative…
- Trial name
- NCT06770985
- Testing
- Artificial Intelligence
- Where
- Turkey (Türkiye)
- Volunteers
- 601 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Lung Transplant Failure
Biomolecular Phenotyping of Lung Transplant Recipients
Primary graft dysfunction (PGD) is a common problem after a lung transplant. It's a sudden lung injury that affects around 30% of patients within 72 hours of getting a new lung.
- Trial name
- LUTX_phenotype (NCT06125535)
- Testing
- Sub-phenotyping by biomarkers concentration
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Policlinico Hospital
Postoperative Pulmonary Complications
Different Algorithm Models to Predict Postoperative Pneumonia in Elderly Patients
The researchers aim to compare different algorithms to predict postoperative pneumonia in elderly patients and to assess the risk of pneumonia in elderly patients.
- Trial name
- NCT05671926
- Volunteers
- 10,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Subcutaneous Treprostinil as a Bridge to Lung Transplantation in Severe Pulmonary Hypertension: A Single-Arm Retrospective Study
This single-arm, retrospective study aims to evaluate the safety and efficacy of subcutaneous treprostinil as a bridge therapy for lung transplantation in patients with severe pulmonary hypertension (PH).
- Conditions
- Pulmonary Hypertension, Pulmonary Arterial Hypertension, Chronic Lung Disease-Associated Pulmonary Hypertension, Lung Transplantation
- Trial name
- NCT06605326
- Testing
- Subcutaneous Treprostinil
- Volunteers
- 46 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Postoperative Pulmonary Complications (PPCs)
Impact of Lung Function Prehabilitation to Postoperative Pulmonary Complications
The aim of this study is to compare the effect of lung function prehabilitation to postoperative pulmonary complications on patient undergoing upper abdominal surgery treated in intensive care unit.
- Trial name
- NCT06862076
- Testing
- Lung Function Prehabilitation
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Breast Cancer, COVID-19
Timing of Surgery and the Evolution of Postoperative Outcomes in Breast Cancer Patients Undergoing Surgical Intervention Following Recovery From SARS-CoV-2 Infection
Perioperative SARS-CoV-2 infection significantly increases the risk of postoperative complications and mortality, while also exerting long-lasting impacts on multiple organs and systems.
- Conditions
- Breast Cancer, COVID-19, Postoperative Complications
- Trial name
- NCT06319209
- Testing
- Preoperative resolved COVID-19
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Fujian Medical University Union Hospital