Clinical trials: Postoperative Pulmonary Complication
Obesity, Morbid, Complications of Bariatric Procedures
The Effect of Postoperative Incentive Spirometry on Pulmonary Function and Pulmonary Complications in Bariatric Surgery
This study evaluates the omission of incentive spirometry use following bariatric surgery. Half of participants will receive an incentive spirometer while the other half will not.
- Conditions
- Obesity, Morbid, Complications of Bariatric Procedures, Pulmonary Atelectasis, Pneumonia
- Trial name
- NCT02431455
- Testing
- Incentive spirometer, No incentive spirometer
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Coronary; Ischemic, Arrhythmias, Cardiac
Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality
With the increasing aging population demographics and life expectancies, the number of very elderly patients undergoing surgery is rising.
- Conditions
- Coronary; Ischemic, Arrhythmias, Cardiac, Heart Failure, Peripheral Vascular Diseases
- Trial name
- OPTI-AGED (NCT02668250)
- Testing
- OPTI-AGED, Usual Care
- Where
- 29 sites in France
- Volunteers
- 2,495 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Lung Transplant Rejection, Primary Graft Dysfunction
Exhaled Breath Particles in Lung Transplantation
Lung transplantation (LTx) is the only effective treatment for patients with end stage lung disease. Of the major organs transplanted, survival following LTx is the lowest with a mean of 5 years.
- Conditions
- Lung Transplant Rejection, Primary Graft Dysfunction, Chronic Rejection of Lung Transplant
- Trial name
- NCT05375149
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University Hospital
End Stage Liver Disease, Lung Cancer
Antinociceptive Modalities on Ischemia Reperfusion Injury
Postoperative pain caused by surgery-associated tissue injury is a major concern for all the clinical practitioners. Because it affects multiple systems and induces physiological, immunological and psychological changes.
- Trial name
- NCT01932918
- Testing
- Patient controlled analgesia
- Where
- Taiwan
- Volunteers
- 142 people
- Sponsor
- National Taiwan University Hospital
Moderated-high Risk of Postoperative Pulmonary Complication, Abdominal Surgery Expected More Than Two Hours
Individualized Perioperative Open Lung Ventilatory Strategy
The purpose of this study is to determine whether individualized ventilatory management combining the use of low tidal volumes, alveolar recruitment maneuvers, individually titrated positive end-expiratory pressure and…
- Trial name
- iPROVE (NCT02158923)
- Testing
- Alveolar recruitment maneuver, Calculation of optimal PEEP, Postoperative CPAP
- Where
- 7 sites in United States, Argentina and 2 more
- Volunteers
- 920 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Postoperative Sleep Disturbances, Chronic Post-surgical Pain
Effectiveness of Perioperative Percutaneous Acupuncture on Postoperative Sleep Disturbances and Chronic Pain in Patients Undergoing Video-Assisted Thoracoscopic Lung Cancer Resection: A Prospective, Randomized, Single-Blind, Superiority Controlled Trial
This study evaluates whether acupuncture at specific body points before and after surgery can improve sleep quality and reduce long-term postoperative pain in patients undergoing video-assisted thoracoscopic lung cancer…
- Trial name
- PASA-VATS (NCT07662733)
- Testing
- Percutaneous Acupoint Acupuncture
- Where
- 2 sites in China
- Volunteers
- 316 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Postoperative Pain
Comparison of Continuous ESP Versus TEA After Thoracotomy
This prospective, randomized, assessor-blinded study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided continuous erector spinae plane (ESP) block in patients undergoing thoracotomy.
- Trial name
- NCT05008614
- Testing
- Erector spinae plane block group, Thoracic epidural analgesia group
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Seoul National University Hospital
Pulmonary Nodule, Pneumothorax
Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection
Brief Summary The goal of this clinical trial is to evaluate the safety and recovery outcomes of different tubeless strategies in adult patients undergoing uniportal video-assisted thoracoscopic (VATS) wedge resection who are…
- Conditions
- Pulmonary Nodule, Pneumothorax, Postoperative Complications
- Trial name
- NCT07395349
- Testing
- Conventional Chest Tube Drainage, Single Intraoperative Aspiration Tubeless, Double Intraoperative Aspiration Tubeless
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Postoperative Pulmonary Complications (PPCs)
Feasibility of Measuring Volume of Inspiration Via Noninvasive Motion Sensors
Background: Lung problems develop in up to 20% of people after they have surgery. While under general anesthesia, people breathe slower and draw in less air.
- Trial name
- NCT06609616
- Testing
- Motion Sensor, Incentive Spirometer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Spinal Fusion, Transfusion
Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications
Elective spine surgery is associated with a high incidence of perioperative complications, including peri- and postoperative pulmonary complications (PPCs), which occur in nearly 4% of patients.
- Conditions
- Spinal Fusion, Transfusion, Pulmonary Complication
- Trial name
- NCT05661838
- Testing
- transfusion
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Lung Transplant; Complications
Vasoactive-inotropic Support and Levosimendan Use After Lung Transplantation
Bilateral Lung transplantation (LUTX) is performed in selected patients with end-stage respiratory failure. During surgery, pulmonary arteries are sequentially cross-clamped.
- Trial name
- VASO_LUTX (NCT05702333)
- Testing
- Epinephrine Norepinephrine Dobutamine Dopamine Levosimendan
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Policlinico Hospital
COVID-19, Complication of Anesthesia
Association Between Post-covid Infection Status and Perioperative Morbidity: A Ambispective Cohort Study
With the knowledge of currently transmitted omicron variant being less virulent, over 90 percent of the Chinese population is fully vaccinated, and the Chinese health workers have sufficient experience treating the illness.
- Conditions
- COVID-19, Complication of Anesthesia, Complication of Surgical Procedure, Complication,Postoperative
- Trial name
- NCT05689840
- Testing
- Receiving inpatient surgical intervention
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Peking Union Medical College Hospital
Intestines Cancer, Pulmonary Cancer
Main Postoperative Complications After COVID-19
To explore the relationship between SARS-CoV-2 infection in different time before operation and postoperative main complications (mortality, main pulmonary and cardiovascular complications) 30 days after operation; To determine…
- Conditions
- Intestines Cancer, Pulmonary Cancer, Liver Cancer, Trauma
- Trial name
- NCT05694949
- Volunteers
- 100,000 people
- Sponsor
- RenJi Hospital
Lung Transplant; Complications
Live Music Therapy to Reduce Anxiety, Pain and Improve Sleep in Post-Operative Lung Transplant Patients: a Pilot Study
The purpose of this prospective pilot study is to determine if live music therapy reduces patients' perception of pain and anxiety, reduces benzodiazepine use and pain medication use, length of stay in the ICU, and length of stay…
- Trial name
- NCT04975607
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Texas Southwestern Medical Center
Extubation, Postoperative Complications
Does Positive Pressure Extubation Reduce Postoperative Desaturation?
Single-center, prospective, controlled, parallel, randomized, single-blind study comparing the conventional extubation technique to two positive pressure extubation techniques on postoperative desaturations
- Conditions
- Extubation, Postoperative Complications, Lung Ultrasound Score
- Trial name
- EXTUBPOS (NCT05295095)
- Testing
- positive pressure during extubation procedure
- Where
- France
- Volunteers
- 264 people
- Sponsor
- University Hospital, Lille
Malignant Mesothelioma, Perioperative/Postoperative Complications
Radiation Therapy in Preventing Metastatic Cancer in Patients Who Have Diagnostic Procedures to Identify Malignant Mesothelioma
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known if radiation therapy is effective in preventing metastatic cancer following surgery.
- Trial name
- NCT00006231
- Testing
- quality-of-life assessment, standard follow-up care, radiation therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 44 people
- Sponsor
- University of Glasgow
Postoperative Pain, Single-incision Thoracoscopic Surgery
Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery
This is a single center, randomized, single blind study to compare the analgesic effect of different anesthesia and postoperative analgesic methods in uniportal VATS lung surgery.
- Trial name
- CDAAMIUVLS (NCT03311737)
- Testing
- general anesthesia, epidural anesthesia
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Zhongshan Hospital
Surgery, Pneumonia
Multicenter Infection Surveillance Study Following Open Heart Surgery
The main goals of the study are as follows: (1) to determine the correlation between pain management using continuous infusion of local anesthetics and the incidence of pneumonia and surgical infection in cardiac surgery…
- Conditions
- Surgery, Pneumonia, Surgical Site Infection
- Trial name
- NCT00673712
- Testing
- Continuous Sternal Block, Opioid based analgesia
- Where
- 8 sites in United States
- Volunteers
- 647 people
- Sponsor
- Halyard Health
Lung-protective Ventilation
Lung-protective Ventilation During Robot-assisted Laparoscopic Radical Cystectomy
Robot-assisted laparoscopic radical cystectomy (RARC) increases the incidence of postoperative complications. We conducted a study to determine the effect of lung-protective ventilation strategy.
- Trial name
- LPV-RARC (NCT03868319)
- Testing
- lung protective ventilation strategy, nonprotective ventilation
- Where
- China
- Volunteers
- 258 people
- Sponsor
- RenJi Hospital
Lung Neoplasms
The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer
The purpose of this study is to examine the impact of physical activity on the postoperative symptoms, complication, and quality of life.
- Trial name
- NCT03705546
- Where
- South Korea
- Volunteers
- 1,050 people
- Sponsor
- Samsung Medical Center