Clinical trials: Postoperative Recovery After Cardiac Surgery
Valvular Heart Disease
The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass
This study evaluates the enhanced recovery after surgery (ERAS) concept over conventional postoperative care in patients with heart valve disease undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- ERAS (NCT02479581)
- Testing
- ERAS group, Conventional control group
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Xiangya Hospital of Central South University
Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure
Serum Phosphatemia Predictive Marker for AKI Diagnosis After Cardiac Surgery
Cardiac surgery associated acute kidney injury is an independent factor of morbidity and mortality . Despite its delayed elevation, serum creatinine (Cr) remains the goal standard to diagnose AKI.
- Conditions
- Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure, Complete Serum Creatinine Measure
- Trial name
- PhosphoIRA (NCT02900313)
- Testing
- cardiac surgery
- Where
- France
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Pain, Post Operative Analgesia
The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery
The goal of this single-center, pragmatic, randomized, blinded, placebo-controlled trial is to evaluate the impact of intravenous (IV) lidocaine within the existing Enhanced Recovery After Surgery (ERAS)program on outcomes in…
- Conditions
- Pain, Post Operative Analgesia, Opioid Consumption, Postoperative
- Trial name
- IMPALA ERAS (NCT07224711)
- Testing
- Lidocaine HCl 0.8% in D5W, Dextrose 5% in water
- Where
- United States
- Volunteers
- 2,290 people
- Sponsor
- Vanderbilt University Medical Center
Heart Transplant
Non-Intubated Anesthesia for Adult Heart Transplantation
This prospective, multicenter, randomized controlled trial aims to evaluate whether non-intubated spontaneous ventilation anesthesia (NISVA) supported by a supraglottic airway can reduce cardiopulmonary complications and promote…
- Trial name
- NISVA-HTx (NCT07758894)
- Testing
- Non-Intubated Spontaneous Ventilation Anesthesia, Conventional Anesthesia, Standardized Perioperative Anesthetic and Analgesic Medication Regimen
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Delirium - Postoperative, Agitation
Responsive Nature-Driven Imagery to Reduce Delirium After Cardiac Surgery
The goal of this clinical trial is to learn if a novel device (MindfulGarden) is beneficial in a population of patients undergoing cardiac surgery.
- Conditions
- Delirium - Postoperative, Agitation, Anxiety, Cardiac Surgery Recovery
- Trial name
- RESPITE (NCT07051096)
- Testing
- A novel device developed providing nature-driven responsive imagery that responds to the patient's physiological to distract, engage, and de-escalate behaviours of delirium., Routine post-operative management and standard delirium reduction measures.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft (CABG)
Effects of a Recovery-Promoting Program in Patients Undergoing CABG Surgery
Patients undergoing coronary artery bypass graft (CABG) surgery often experience physical limitations, psychological stress, and challenges during recovery after hospital discharge.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft (CABG), Postoperative Recovery
- Trial name
- NCT07392021
- Testing
- Recovery Promotion Program for CABG patients, Standard Postoperative CABG Care
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Analgesia, Surgery
High Versus Low Dose Serratus Anterior Plane Block After Minimally Invasive Valve Surgery.
This study aims to compare the efficacy and quality of pain relief provided by the high-dose serratus anterior plane (SAP) block with the standard SAP block in preventing and treating acute postoperative pain after total…
- Conditions
- Analgesia, Surgery, Cardiac Disease, Post Operative Pain
- Trial name
- NCT06205875
- Testing
- High dose serratus anterior plane block (2.4 mg/kg patient ideal body weight), Low dose serratus anterior plane block (1.2mg/kg patient ideal body weight), PCIA with morphine
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Pericardial Effusion, Inflammatory Response After Surgery
Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window
Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation.
- Conditions
- Pericardial Effusion, Inflammatory Response After Surgery, Postoperative Complications, Procedural Sedation and Analgesia
- Trial name
- RNIVATS (NCT07800767)
- Testing
- Systemic opioid-based analgesia during NIVATS, Thoracic regional analgesia during NIVATS
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Cardiac Surgery Patients
High-dose Opioid Versus Opioid-sparing Anaesthesia in Cardiac Surgery
BACKGROUND In cardiac surgery, high-dose opioid contributes to adverse events associated with poor postoperative outcomes. There is growing evidence that nerve block-based multi-modal anesthesia protocols may reduce…
- Trial name
- NCT06437886
- Testing
- opioid-sparing protocol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Enhanced Recovery After Surgery, Open Heart Surgery
The Effect of Advanced Improvement Program (ERAS) on Postoperative Outcomes in Patients Undergoing Open Heart Surgery
Investigation of the effect of Enhanced Recovery After Surgery (ERAS) program on postoperative results of patients operated for open heart surgery.
- Trial name
- NCT03799965
- Testing
- ERAS (Enhanced Recovery After Surgery ) are evaluated, ERAS are not evaluated
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Mechanical Ventilation, Cardiac Surgery
Planned Operating-Room Extubation After Cardiac Surgery
The goal of this clinical trial is to learn whether removing the breathing tube in the operating room after cardiac surgery helps adults recover faster than removing the breathing tube later in the intensive care unit (ICU)…
- Conditions
- Mechanical Ventilation, Cardiac Surgery, Fast Track Program,(Enhanced Recovery After Surgery (ERAS))
- Trial name
- NCT07874607
- Testing
- Planned Operating-Room Extubation, Standard Early ICU Extubation
- Where
- 2 sites in Canada
- Volunteers
- 336 people
- Sponsor
- Nova Scotia Health Authority
Postoperative Quality of Recovery, Postoperative Quality of Recovery in the Postanesthesia Care Unit
Quality of Recovery in the Post-anesthesia Care Unit
This prospective observational study aims to identify the minimal clinically important difference of the QoR-PACU2 questionnaire.
- Trial name
- MiDiQoR (NCT06905353)
- Volunteers
- 188 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cardiac Surgery, Enhanced Recovery After Surgery
The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in Adult
Among adults, patients undergoing elective extracorporeal circulation for cardiac surgery are included in the ERAS strategy intervention plan, which mainly includes preoperative education, preoperative oral intake of…
- Trial name
- NCT05914090
- Testing
- ERAS
- Where
- 2 sites in China
- Volunteers
- 3,600 people
- Sponsor
- Yan Fuxia
Cardiac Surgery, Adult
Erector Spinae Plane Block and Pain Management in Cardiac Surgery
Evaluation of the benefit effects of Peri-Operative analgesia by Continuous Bilateral Erector Spinae Plane block(ESP) for Open Cardiac Surgery: A case series prospective study with a comparison a retrospective case series (Before…
- Trial name
- ESPCATHEART (NCT03541837)
- Testing
- Ropivacaine
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Vinmec Healthcare System
Patients Undergoing Open Heart Surgery, Patients Undergoing Lung Surgery
CAM in Post Surgical Management in Cardiothoracic Surgery
This is a randomized controlled clinical trial in which the combination of 4 different CAM modalities (Complementary \& Alternative Medicine) will be applied during the postoperative period to patients undergoing open heart- or…
- Trial name
- NCT01650363
- Testing
- Acupuncture, homeopathy, osteopathy- and reflexology
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Postoperative Recovery, Cardiac Surgery
Development, Validation and Clinical Application of a Recovery Scale After Cardiac Surgery: the Fuwai-CRS (Fuwai- Cardiac Recovery Scale)
Improving patient recovery after cardiac surgery is a critical priority. While improved surgical techniques have substantially reduced procedural mortality over the past decades, the inherent physiological insult of median…
- Conditions
- Postoperative Recovery, Cardiac Surgery, PROM
- Trial name
- NCT05782036
- Where
- China
- Volunteers
- 3,043 people
- Sponsor
- China National Center for Cardiovascular Diseases
Systemic Inflammatory Response Syndrome, Acute Kidney Injury
High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery
A high cut off dialyzer (septeX) is tested in patients after cardio-thoracic surgery with incidence of "systemic inflammatory response syndrome" (SIRS) and associated increased risk for acute kidney injury (AKI).
- Trial name
- HICOSIRS (NCT01579396)
- Testing
- septeX, standard therapy
- Where
- Germany
- Sponsor
- Vantive Health LLC
Heart Valve Diseases
Interdisciplinary Perioperative Care in Minimally-invasive Heart Valve Surgery
Valvular heart diseases are among the most common cardiac pathologies in adult patients in Germany. Currently, the process of care before, during and after heart valve surgery does not follow a standardized and interdisciplinary…
- Trial name
- INCREASE (NCT04977362)
- Testing
- Enhanced Recovery After Surgery, Treatment as Usual
- Where
- 2 sites in Germany
- Volunteers
- 201 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Functional Recovery After Cardiac Surgery : Does Delirium and Calorie Intake Matter?
The aims of the cohort study is to describe the rates of 30-day surgical complication, functional decline, frailty and one-year mortality for patients experienced cardiac surgery and to delineate the trajectory of functional…
- Trial name
- NCT02212509
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Sternal Closure
Montage-Enhanced Sternal Closure
Post-operative recovery after cardiac surgery is influenced by early sternal bone stability. Traditional sternal closure of median sternotomy usually entails the use of 6-10 stainless steel wires.
- Trial name
- NCT03365843
- Testing
- Montage bone putty, Conventional Sternal Closure
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Calgary