Clinical trials: Postoperative Renal Complication
Cardiac Surgery, Intraoperative Hemodynamic Instability
Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery
Intraoperative hemodynamic instability (IOHI) is a common occurrence during cardiac surgery and is associated with organ hypoperfusion. However, the specific impact of IOHI on composite adverse outcomes remains unclear.
- Conditions
- Cardiac Surgery, Intraoperative Hemodynamic Instability, Postoperative Complication, Acute Kidney Injury
- Trial name
- NCT07324694
- Where
- Turkey (Türkiye)
- Volunteers
- 351 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Ischemia Reperfusion Injury
The Renal Transplant Outcome Prediction and Validation Study
The number of patients with end stage renal disease is increasing continuously and kidney transplantation is the preferred treatment modality.
- Trial name
- TOPVAS (NCT03978065)
- Testing
- Confocal microscopy
- Volunteers
- 113 people
- Sponsor
- Medical University Innsbruck
Kidney Transplantation
A Study to Evaluate the Effect of ASP8597 in Adult Kidney Transplant Patients
The purpose of this study is to evaluate the efficacy, safety and tolerability of a single intravenous dose of ASP8597 in kidney transplant recipients.
- Trial name
- NCT01442337
- Testing
- ASP8597
- Where
- 19 sites in United States
- Volunteers
- 21 people
- Sponsor
- Astellas Pharma Inc
Kidney Stones
7.5F Versus 9.2F Flexible Ureteroscopy for the Treatment of 1-2cm Renal Calculi on Postoperative Infection
Ureteroscopic lithotripsy (RIRS) is the first-line treatment for 1-2 cm upper urinary tract stones, and the stone clearance rate can reach 81.4% - 92.5%.
- Trial name
- NCT05231577
- Testing
- 7.5fr ultra-fine ureteroscopy, 9.2fr Ureteroscopy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Transplant; Complications, Pain, Postoperative
Postoperative Pain Control Following Renal Transplant
This study aims to compare the effectiveness of a regional anesthetic block vs systemic intravenous (IV) lidocaine in controlling post-operative pain in kidney transplantation patients.
- Trial name
- NCT05044429
- Testing
- Intravenous Lidocaine, Transversus abdominis plane (TAP) block, Quadratus Lumborum (QL) Block
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- George Washington University
Nephrectomy
Anesthesia and Acute Kidney Injury After Nephrectomy
This study investigates the influence of type of anesthesia on postoperative renal dysfunction in patients undergoing nephrectomy.
- Trial name
- NCT04474600
- Testing
- Propofol, Desflurane
- Where
- South Korea
- Volunteers
- 324 people
- Sponsor
- Seoul National University Hospital
Liver Diseases, Kidney Diseases
Hypothermic Oxygenated Perfusion Versus Static Cold Storage for Marginal Graft
One of the major challenge in the field of organ transplantation is the shortage of donor organs. Many patients waiting for organ transplantation die during the waiting time and many patients wait for organ transplantation many…
- Trial name
- PIO (NCT03031067)
- Testing
- Machine perfusion
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Matteo Ravaioli
Acute Ischemic Stroke, Acute Renal Injury
Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation
The aim of this trial is to assess the safety and efficacy of conestat alfa (Ruconest®, Pharming Technologies B.V.) on renal and cerebral ischemic events in patients undergoing TAVI for severe symptomatic aortic stenosis (AS)…
- Trial name
- PAIR-TAVI (NCT05145283)
- Testing
- Conestat alfa (Ruconest®), NaCl 0.9%)
- Where
- 2 sites in Switzerland
- Volunteers
- 141 people
- Sponsor
- University Hospital, Basel, Switzerland
Aortic Surgery, Acute Kidney Injury
The Effect of Atorvastatin on Prevention of Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery
Acute kidney injury(AKI) is a common and severe complication after the cardiac surgery. Postoperative AKI increases the in-hospital stay, intensive care unit(ICU) stay and postoperative mortality.
- Trial name
- NCT02157337
- Testing
- Atorvastatin
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Yonsei University
Post Operative Pain
Combined Supraclavicular Block and General Anesthesia in Pediatric Patients With Chronic Kidney Disease
compare the safety and efficacy of ultrasound-guided supraclavicular block in addition to general anesthesia in pediatric patients undergoing upper limb superficialization of arteriovenous fistula for hemodialysis.
- Trial name
- NCT05580094
- Testing
- general anesthesia only., general anesthesia plus supraclavicular block.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Kidney Calculi, Nephrolithiasis
Supine vs. Prone PCNL for Large Renal Stones: A Randomized Trial in Yemen.
The goal of this clinical trial is to compare the safety, cost-effectiveness, and patient recovery of two different surgical positions for percutaneous nephrolithotomy (PCNL) in adults aged 18 to 70 years who have kidney stones…
- Trial name
- NCT07627503
- Testing
- Supine Percutaneous Nephrolithotomy (PCNL), Prone Percutaneous Nephrolithotomy (PCNL)
- Where
- Yemen
- Volunteers
- 140 people
- Sponsor
- Sana'a University
Renal Cell Carcinoma
Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study
patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block, and the quadratus lumborum block.
- Trial name
- NCT05810571
- Testing
- preoperative remifentanil consumption, postopeartive controlled anlagesia with morphine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Kidney Calculi, Nephrolithiasis
Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones.
- Trial name
- NCT07749807
- Testing
- Nebulized Glubran 2-Assisted Tubeless PCNL, Conventional PCNL With Nephrostomy Tube
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Renal Cell Carcinoma (Kidney Cancer)
Patient Reported Outcomes and Different Renal Artery Clamping Techniques During Robot Assisted Kidney Resection
The target population for this study consists of all patients undergoing kidney surgery at Haukeland University Hospital, Norway, with the primary focus being patients undergoing robot-assisted partial nephrectomy.
- Trial name
- RAPTOR (NCT07853001)
- Testing
- Standard clamping strategy, Early declamping strategy
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Bjarte Almas
Cardiac Surgery, Extracorporeal Circulation
RRI Compared With NephroCheckTM to Predict Acute Renal Failure After Cardiac Surgery.
Postoperative acute renal failure is a frequent complication after cardiac surgery. The current practice cannot predict Acute Kidney Injuries (AKI) early enough to reduce a significant kidney assault and prevent an organic…
- Conditions
- Cardiac Surgery, Extracorporeal Circulation, Nephrocheck, Renal Failure
- Trial name
- NCT02325726
- Testing
- Renal Resistive Index compared with NephroCheckTM
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Bordeaux
Kidney Function, Kidney Transplant; Complications
Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation
Furosemide is an old drug that has been used frequently in the postoperative period of kidney transplantation, aiming to achieve adequate urine output.
- Conditions
- Kidney Function, Kidney Transplant; Complications, Delayed Graft Function
- Trial name
- FOSTIK (NCT03071536)
- Testing
- Furosemide Injection
- Where
- Thailand
- Volunteers
- 360 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Acute Kidney Injury
Perfusion - Pressure - Creatinine Trial
In Denmark around 3500 procedures are conducted involving a heart-lung-machine per year. An increase in the prevalence of postoperative kidney insufficiency have been observed following these procedures, during the last years.
- Trial name
- PPC (NCT01408420)
- Testing
- MAP > 60 mmHg
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiac Surgery, Vasoplegia
Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II
The study intervention focuses on exploring the use of angiotensin II as a primary vasopressor compared to norepinephrine in cardiac surgery patients to investigate whether angiotensin II can reduce the occurrence of…
- Trial name
- PAN-AKI (NCT06615102)
- Testing
- Angiotensin II, Noradrenalin
- Where
- 4 sites in Germany
- Volunteers
- 1,022 people
- Sponsor
- Universität Münster
Kidney Diseases, Postoperative Complications
High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Nephrectomy
The aim of this study is to investigate the effect of a single preoperative high-dose steroid injection on complications in the immediate postoperative phase after open kidney surgery (kidney resection, heminephrectomy…
- Trial name
- DEX-NEF (NCT03160729)
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ureter Cancer, Renal Pelvic Carcinoma
Postoperative Adjuvant Immunotherapy Combined with Radiotherapy Versus Surgery Alone in Locally Advanced UTUC
This is a prospective cohort study to analyse the safety and efficacy of postoperative adjuvant radiotherapy combined with immunotherapy versus surgery alone group of UTUC patients with T3-4 stages or lymph nodes metastasis(N+)…
- Conditions
- Ureter Cancer, Renal Pelvic Carcinoma, Advanced Urothelial Carcinoma
- Trial name
- NCT06598761
- Testing
- Immunotherapy+radiotherapy, surveillance alone
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital