Clinical trials: Postoperative Renal Complication
Renal Cancer
Laparoscopic Versus Hand Assisted Laparoscopic Trans-peritoneal Laparoscopic Nephrectomy as One Day Surgery (i.e.: Are There Differences in Postoperative Outcome / Convalescence)
The purpose of this study is to describe the postoperative outcomes after laparoscopic transperitoneal nephrectomy and compare them with hand assisted laparoscopic nephrectomy with a focus on the limiting factors that prevent an…
- Trial name
- NCT02295982
- Testing
- Hand assisted laparoscopic nephrectomy
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Zealand University Hospital
Kidney Transplant; Complications, Postoperative Residual Curarization
Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation Surgery
The purpose of this study is to compare two medications that reverse muscle paralysis at the end of kidney transplant surgery with the goal of reducing residual muscle weakness and insufficient respiratory function after surgery.
- Conditions
- Kidney Transplant; Complications, Postoperative Residual Curarization, Postoperative Residual Weakness
- Trial name
- NCT03923556
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Colorado, Denver
AKI - Acute Kidney Injury, PAI-1 4G/5G Polymorphism
Correlation Study of PAI-1 4G/5G Polymorphism and Postoperative AKI in Patients With Aortic Dissection
To explore the association between PAI-1 4G5G polymorphism and the risk of CSA-AKI in Stanford type A dissection patients undergoing open-heart repair surgery.
- Conditions
- AKI - Acute Kidney Injury, PAI-1 4G/5G Polymorphism, Aortic Dissection
- Trial name
- NCT05490394
- Where
- China
- Volunteers
- 283 people
- Sponsor
- Xijing Hospital
Kidney Cancer, Long-term Effects Secondary to Cancer Therapy in Adults
Warm Ischemia or Cold Ischemia During Surgery in Treating Patients With Stage I Kidney Cancer
RATIONALE: Warm ischemia is the clamping of blood vessels without cooling the kidney. Cold ischemia is the clamping of blood vessels with kidney cooling.
- Conditions
- Kidney Cancer, Long-term Effects Secondary to Cancer Therapy in Adults, Perioperative/Postoperative Complications, Urinary Complications
- Trial name
- NCT00743236
- Testing
- cold ischemia procedure, warm ischemia procedure
- Where
- 8 sites in United States
- Volunteers
- 1 people
- Sponsor
- Wake Forest University Health Sciences
Transplant Complication, Diabetic Nephropathy
Enhanced Recovery After Surgery for SPK Transplantation Recipients
108 patients underwent elective SPK surgery were randomly divided into ERAS group (E) and routine care group (T). The ERAS group was consisted of evidenced-based systematic optimization approaches, while the control group…
- Conditions
- Transplant Complication, Diabetic Nephropathy, Perioperative/Postoperative Complications
- Trial name
- NCT06095544
- Testing
- Enhanced recovery for SPK recipients
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Sepsis, Acute Kidney Injury
Immune Evaluation for Postoperative Sepsis-AKI
This prospective, multicenter, observational cohort study plans to enroll over 800 patients with postoperative sepsis from the ICUs of two tertiary hospitals in Beijing.
- Trial name
- NCT07811544
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Beijing Chao Yang Hospital
Kidney Transplant; Complications, Diabetes Mellitus, Type 2
CardioRenal Effects of SGLT2 Inhibition in Kidney Transplant Recipients
CREST-KT is a single-center, double-blinded, randomized trial of empagliflozin therapy in 72 kidney transplant recipients with (n=36) and without type 2 diabetes (n=36).
- Trial name
- CREST-KT (NCT04906213)
- Testing
- Empagliflozin10Mg Tab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Acute Renal Failure
Development and Validation of an Enhanced Prediction Score for Postoperative Acute Renal Failure After Liver Resection
Post-operative acute renal failure is a severe post-operative complication and is associated with high mortality. The enhanced prediction score, including pre-as well as intra-operative predictors accurately predicted ARF…
- Trial name
- NCT01318798
- Where
- Switzerland
- Volunteers
- 549 people
- Sponsor
- University of Zurich
Acute Kidney Injury, Pneumonectomy; Status
Evaluation of Postoperative Acute Kidney Injury (AKI) Incidence and Risk Factors in Patients Underwent Pneumonectomy
Acute kidney injury (AKI) is a critical complication associated with a high incidence of morbidity and mortality that can occur in critically ill patients and after major surgical procedures.
- Conditions
- Acute Kidney Injury, Pneumonectomy; Status, Complication,Postoperative
- Trial name
- NCT05672238
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people
- Sponsor
- Ankara University
Acute Kidney Injury
Application of Intraoperative Transesophageal Echocardiography Imaging of Vein and CLCVP in Early Prediction and Intervention CSA-AKI
The goal of this clinical trial is to learn about in postoperative acute kidney injury in cardiac surgery. The main questions it aims to answer are: Intraoperative Transesophageal Ultrasound Doppler venous imaging can be used to…
- Trial name
- NCT05682716
- Testing
- Controlled low central venous pressure (CLCVP) technology, Nitroglycerin
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Thoracic Surgery, Acute Kidney Injury
Influence of Preoperative Fluid Intake on the Onset of Postoperative Acute Kidney Injury
To investigate the influence of preoperative fluid and food intake in cardiac surgery patients on the development of postoperative AKI.
- Conditions
- Thoracic Surgery, Acute Kidney Injury, Critical Care
- Trial name
- HYDRATE-CSX (NCT03938181)
- Where
- Germany
- Volunteers
- 320 people
- Sponsor
- RWTH Aachen University
Postoperative Pain, Acute
Comparison of Transversus Abdominis Plane and Erector Spinae Plane Blocks for Pain Control After Renal Laparoscopy
The goal of this study is to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries.
- Trial name
- TAP-ESPB (NCT07781930)
- Testing
- TAP Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure
Serum Phosphatemia Predictive Marker for AKI Diagnosis After Cardiac Surgery
Cardiac surgery associated acute kidney injury is an independent factor of morbidity and mortality . Despite its delayed elevation, serum creatinine (Cr) remains the goal standard to diagnose AKI.
- Conditions
- Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure, Complete Serum Creatinine Measure
- Trial name
- PhosphoIRA (NCT02900313)
- Testing
- cardiac surgery
- Where
- France
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Kidney Transplantation, Delirium - Postoperative
A Predictive Model for Postoperative Delirium in Kidney Transplant Patients
This study aims to develop and prospectively validate a machine learning-based prediction model for postoperative delirium in kidney transplant recipients, using perioperative clinical data.
- Conditions
- Kidney Transplantation, Delirium - Postoperative, Cognitive
- Trial name
- NCT07078578
- Volunteers
- 4,800 people
- Sponsor
- Hua Zheng
Urolithiasis
COMPARISON OF FANS VS CONVENTIONAL URETERAL ACCESS SHEATH in RIRS on POSTOPERATIVE ACUTE KIDNEY INJURY
Kidney stone disease is a common condition, and retrograde intrarenal surgery (RIRS) is a minimally invasive procedure frequently used to remove kidney stones.
- Trial name
- FANS (NCT07685587)
- Testing
- flexible and navigable ureteral access sheath, conventional ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Namik Kemal University
Acute Kidney Injury, Cardiac Surgery
proMoting Effective Renoprotection in Cardiac sURgery Patients by Inhibition of SGLT-2
Multi-centre, triple-blinded (patients, physicians, investigators), parallel-group, balanced (1:1), stratified (sex, type 2 diabetes mellitus), randomized, controlled (placebo), phase IV clinical trial to investigate the…
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Sodium-Glucose Transporter 2 Inhibitor
- Trial name
- MERCURI-2 (NCT05590143)
- Testing
- Dapagliflozin 10 MG Oral Tablet [Farxiga]
- Where
- 6 sites in Netherlands
- Volunteers
- 784 people
- Sponsor
- Amsterdam UMC
Retrograde Intrarenal Surgery, Renal Stones
Retrograde Intrarenal Surgery Low Risk Trial
In the treatment of kidney stones and upper ureteral stones, flexible ureteroscopic lithotripsy has become the mainstream choice due to its minimally invasive nature and high safety.
- Trial name
- NCT06741917
- Testing
- Levofloxacin, Cefmetazole (drug)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Scheduled Cardiac Surgery With Extracorporeal Circulation, Vasoplegic Syndrome
Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal Circulation
This is a randomized, double blind, multicenter study following surgery with extracorporeal circulation to compare blood pressure optimization with vasopressin versus noradrenaline.
- Trial name
- NOVACC (NCT05568160)
- Testing
- Vasopressin, Norepinephrine, Collection of clinical data
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Localized Renal Pelvis and Ureter Urothelial Carcinoma, Locally Advanced Bladder Urothelial Carcinoma
Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer
This phase III trial studies how well pembrolizumab works in treating patients with bladder cancer that has spread into the deep muscle of the bladder wall (muscle-invasive) or urothelial cancer that has spread from where it…
- Conditions
- Localized Renal Pelvis and Ureter Urothelial Carcinoma, Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis and Ureter Urothelial Carcinoma, Locally Advanced Ureter Urothelial Carcinoma
- Trial name
- AMBASSADOR (NCT03244384)
- Testing
- Biospecimen Collection, Clinical Observation, Computed Tomography
- Where
- 914 sites in United States, Guam
- Volunteers
- 739 people
- Sponsor
- National Cancer Institute (NCI)
Non-Dialysis Dependent Severe Renal Dysfunction, Cardiovascular Disease
Preop Hemodialysis or Intraop Ultrafiltration for Patients With Severe Renal Dysfunction Undergoing Open Heart Surgery
The purpose of this study is to determine whether preoperative hemodialysis or intraoperative modified ultrafiltration are effective for patients with non-dialysis dependent severe renal dysfunction undergoing open heart surgery.
- Trial name
- SeRenaD-CPB (NCT00720967)
- Testing
- Open Heart Surgery (OHS), Intraoperative Modified Ultrafiltration (MUF), Hemodialysis (HD)
- Where
- 7 sites in France, Germany and 3 more
- Volunteers
- 450 people
- Sponsor
- University Hospital, Geneva