Clinical trials: Postoperative Respiratory Complication
Postoperative Pain, Postoperative Nausea and Vomiting
The Effect of Pharyngeal Cooling Applications on Postoperative Throat Pain and Nausea Vomiting
The goal of this observational study is to to evaluate the effects of a throat pack soaked with saline at +4 ºC on postoperative throat pain (POTP) and postoperative nausea and vomiting (PONV) in dental surgical procedures…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Throat, Sore, Anesthesia
- Trial name
- NCT06271161
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Tonsillectomy, Tonsillitis
EXPAREL® for Pain After Tonsillectomy
The purpose of this study is to determine whether liposomal bupivacaine (long acting injectable anesthetic) provides greater post operative pain relief compared to the standard post operative pain regiment for tonsillectomy…
- Conditions
- Tonsillectomy, Tonsillitis, Post-operative Pain
- Trial name
- NCT02444533
- Testing
- Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Respiratory Insufficiency, Pneumonia
Diaphragm Dysfunction and Ultrasound Perioperatively
This study aims at determining whether diaphragm ultrasound examining diaphragm thickening fraction, excursion and density before and after surgery can predict respiratory complications in the postoperative period.
- Conditions
- Respiratory Insufficiency, Pneumonia, Desaturation of Blood, Tachypnea
- Trial name
- DiaphPeriop (NCT05906030)
- Testing
- Diaphragm ultrasound
- Where
- 2 sites in Sweden
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Respiratory Complications
Risk Factors for Post-Operative Respiratory Complications in Patients at Risk for OSA
This study investigates the incidence of postoperative respiratory complications (PRCs) including: oxygen desaturation events, tracheal re-intubations within 48 hours of surgery, and failure to wean from ventilator within 48…
- Trial name
- NCT02729077
- Testing
- Pulse Oximetry
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Thoracic Surgery, Low-flow Anesthesia
Effect of Low-Flow Anesthesia in Single Lung Ventilation on Postoperative Respiratory Complications
Mechanical ventilation in thoracic surgery patients is often complicated because patients are usually in the lateral decubitus position and the operated lung is intermittently deflated to facilitate surgical exposure .
- Trial name
- Low-Flow Anest (NCT06838091)
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Complications
Application of Capnography Monitoring on the General Care Nursing Unit
The aim of this study is to increase the detection of undiagnosed obstructive sleep apnea (OSA) and secondly to increase the sensitivity for detection of respiratory depression (< 6 breaths per minute) in post operative patients…
- Trial name
- ETCO2 (NCT00457080)
- Testing
- Alaris ETCO2 monitor - cont. resp. rate, & apnea events
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas Health Resources
Obesity, Postoperative Bariatric Surgery
Lung Ultrasound Evaluation of the Effects of PEEP and Recruitment Strategies Adjusted for Intraoperative Dynamic Compliance on Postoperative Respiratory Complications in Obese Patients Planned for Laparoscopic Surgery
This study aims to investigate the effects of the personalized application of respiratory pressures applied to patients undergoing laparoscopic bariatric surgery when they are connected to a ventilator under general anesthesia…
- Conditions
- Obesity, Postoperative Bariatric Surgery, Laparoscopic Surgery, Individualized PEEP Treatment Strategy
- Trial name
- NCT06994780
- Testing
- dynamic compliance guided PEEP titration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Thrombophilia Associated With Pregnancy, Perioperative/Postoperative Complications
Thromboprophylaxis in Pregnant Women in Hospital: A Prospective Clinical Trial
Hospitalization in pregnancy and childbirth greatly increases the thromboembolic risk of these patients. The application of a protocol for assessing the risk of VTE reduces mortality and morbidity of these phenomena.
- Conditions
- Thrombophilia Associated With Pregnancy, Perioperative/Postoperative Complications, Venous Thrombosis, Pulmonary Embolism
- Trial name
- NCT02600260
- Testing
- Enoxaparin, No intervention
- Where
- Brazil
- Volunteers
- 7,212 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Postoperative Complications, Breathing Exercises
Randomized-controlled Trial of Preoperative Inspiratory Muscle Training on Postoperative Complications
Rehabilitation strategies after abdominal surgery enhance recovery and improve outcome. A cornerstone of rehabilitation is respiratory physiotherapy with inspiratory muscle training to enhance pulmonary function.
- Conditions
- Postoperative Complications, Breathing Exercises, Preoperative Period
- Trial name
- INSPIRA (NCT04558151)
- Testing
- preoperative inspiratory muscle training
- Where
- Switzerland
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Obesity, Morbid, Complications of Bariatric Procedures
The Effect of Postoperative Incentive Spirometry on Pulmonary Function and Pulmonary Complications in Bariatric Surgery
This study evaluates the omission of incentive spirometry use following bariatric surgery. Half of participants will receive an incentive spirometer while the other half will not.
- Conditions
- Obesity, Morbid, Complications of Bariatric Procedures, Pulmonary Atelectasis, Pneumonia
- Trial name
- NCT02431455
- Testing
- Incentive spirometer, No incentive spirometer
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Primary Graft Dysfunction, Lung Transplantation
This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction
Lung transplant recipient survival lags other solid organ recipients, with the main early cause of death being primary graft dysfunction (PGD).
- Conditions
- Primary Graft Dysfunction, Lung Transplantation, Acute Lung Injury(ALI), Natural Killer Cell Mediated Immunity
- Trial name
- MARAVIROC (NCT06853223)
- Testing
- Maraviroc
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Respiratory Complications, Opioid Induced Respiratory Depression
Timing of Opioid Administration and Postoperative Respiratory Depression.
The goal of this study is to determine if a relationship can be detected between the administration of an opioid and quantitative respiratory depression in spontaneously breathing non-intubated patients who have undergone general…
- Conditions
- Respiratory Complications, Opioid Induced Respiratory Depression, Postoperative Respiratory Complications
- Trial name
- NCT07227389
- Testing
- Respiratory volume monitoring
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Pain, Postoperative, Pulmonary Atelectasis
Paravertebral Block Versus Erector Spinae Plane Block for Modified Radical Mastectomy in Womens.
postoperative pain following Modified radical mastectomy is severe specially after dissection of tissues .paravertebral plane block provides an excellent postoperative analgesia for women's,but it carry the risk of pneumothorax…
- Conditions
- Pain, Postoperative, Pulmonary Atelectasis, Mastectomy
- Trial name
- NCT03614091
- Testing
- Erector spinae plane block, Paravertebral plane block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ischemia-Reperfusion Injury, Myocardial Infarction
Infusion of a Single Dose of Erythropoietin to Prevent Injury in an Ischemia Reperfusion Forearm Model
Rationale: The investigators hypothesize that EPO protects against apoptosis after acute ischemia in man and that it is detectable using the annexin-A5 model.
- Trial name
- IPIIR (NCT00691613)
- Testing
- Epoetin alpha, NaCl
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Sore-throat, Nasopharyngeal Pack
Effect of Oropharyngeal Pack Soaked in Ketamine or Magnesium Sulphate on Post Operative Sore Throat After Nasal Surgery
The aim of this study is to compare the effect of ketamine or magnesium sulphate soaked throat pack on the incidence and severity of post operative sore throat as a primary outcome, post operative nausea and vomiting as a…
- Conditions
- Sore-throat, Nasopharyngeal Pack, Nasal Surgery, Nausea and Vomiting, Postoperative
- Trial name
- NCT05714540
- Testing
- Ketamine Hydrochloride ,Magnesium sulphate and saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Postoperative Pulmonary Complications
Respiratory Variability for Respiratory Monitoring During the Postoperative Recovery Period
The research consist of measuring respiratory variability of several variables of the respiratory pattern at rest and during exercise using a thoracic movement measuring technique.
- Trial name
- VariaRessPi (NCT04605250)
- Testing
- Respiratory variability before and after surgery
- Where
- Martinique
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Pain, Postoperative Pain
A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries
Post-operative, throat pain, nausea and vomiting is a common occurrence in rhinology surgeries due to the use of throat packs during the procedure.
- Conditions
- Pain, Postoperative Pain, Bleeding, Nose Bleed
- Trial name
- NCT03678168
- Testing
- Throat Pack, Pharyngeal Tampons
- Where
- Bahrain
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- King Hamad University Hospital, Bahrain
Postoperative Pain
Analgesic Efficacy of an Opioid-free Postoperative Pain Management Strategy Versus a Conventional Opioid-based Strategy Following Video-assisted Thoracoscopic Lobectomy
Investigators have designed a randomized controlled trial. Utilizing an open-label, randomized, controlled study methodology, this trial aims to explore a opioid-free, safe, and effective analgesic approach for thoracic surgery.
- Trial name
- NCT06570538
- Testing
- Ropivacaine, Sufentanil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Respiratory Failure, Acute Respiratory Failure Requiring Reintubation
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Intraoperative intravenous fluid management practice varies greatly between anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity.
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Reintubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02105298
- Where
- United States
- Volunteers
- 104,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital