Clinical trials: Postoperative Sleep Quality
Total Knee Arthroplasty (TKA)
Effect of Preoperative Sleep Disturbance on Postoperative Pain and Recovery
The study subjects consisted of patients who underwent elective total knee arthroplasty (TKA) at Gansu Provincial Hospital of TCM from November 2023 to January 2024.
- Trial name
- NCT06815744
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Gansu Provincial Hospital
Obstructive Sleep Apnea, Surgery
Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA
Patients with obstructive sleep apnea (OSA) are at increased risk of developing sleep disturbances after surgery. Dexmedetomidine is a highly selective α2-adrenergic agonist with sedative, analgesic, and anxiolytic effects.
- Conditions
- Obstructive Sleep Apnea, Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT06566482
- Testing
- Dexmedetomidine-esketamine combination
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Surgery, Pain
Perioperative Sleep Quality and Postoperative Pain Outcomes
This is a prospective, observational cohort study that will examine how sleep quality impacts postoperative pain and opioid consumption for pediatric patients.
- Conditions
- Surgery, Pain, Sleep, Spinal Fusion
- Trial name
- NCT06054802
- Testing
- eCAP
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Grant Heydinger
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Breast Cancer Related Lymphedema
Investigation of the Effects of Complex Decongestive Physiotherapy on Sleep Quality and Quality of Life in Women With Breast Cancer Related Lymphedema
Breast cancer is the most common type of cancer among women globally and has the highest mortality rate. Surgical interventions are typically required in the treatment of breast cancer, but these procedures can lead to…
- Trial name
- NCT06697158
- Testing
- Physiotherapy and rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Abant Izzet Baysal University
Sleep Quality Post-TKA, Postoperative Knee Function
Doxepin Alone or Combined With Ramelteon Versus Placebo for Improving Sleep Quality After Primary Total Knee Arthroplasty
Many patients experience poor sleep during recovery after total knee arthroplasty (TKA). Disturbed sleep can last weeks to months and may worsen pain, slow healing, and reduce overall quality of life.
- Conditions
- Sleep Quality Post-TKA, Postoperative Knee Function, Quality of Life After Primary TKA
- Trial name
- NCT07598734
- Testing
- Doxepin 6 mg, Ramelteon 8 mg
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Washington
Chronic Post-Surgical Pain
Effect of Perioperative Sleep Quality on Chronic Post-Surgical Pain
The goal of this prospective observational cohort study is to assess the impact of perioperative sleep quality on the development of chronic post-surgical pain (CPSP) in adult patients (aged 18-80 years, ASA I-III) undergoing…
- Trial name
- NCT06871891
- Where
- China
- Volunteers
- 1,138 people
- Sponsor
- Peking Union Medical College Hospital
Thoracic Surgical Procedures
Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. Three hundred-sixty adult patients undergoing elective thoracoscopic surgery will be randomly allocated at a 1:1 ratio to receive either intraoperative…
- Trial name
- NCT07794982
- Testing
- sodium oxybate
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Jingsheng Lou
Obesity, Sleep Apnea
Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery
The purpose of this study is to determine if Dexmedetomidine given at the end of surgery will reduce postoperative morphine consumption and improve postoperative quality of recovery as compared to morphine in patients undergoing…
- Conditions
- Obesity, Sleep Apnea, Diabetes, Hypertension
- Trial name
- NCT02213159
- Testing
- Dexmedetomidine, Morphine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- American University of Beirut Medical Center
Wrist Injuries, Postoperative Pain Control
Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery
The purpose of this study is to compare infraclavicular brachial plexus shot single shot block to local infiltration done in adult patients having wrist arthroscopy surgery.
- Trial name
- NCT02970097
- Testing
- 20ml bolus of 0.5% ropivicaine, 10 ml of 0.5% ropivicaine, Midazolam
- Where
- United States
- Sponsor
- University of Pennsylvania
Perioperative Anxiety, Postoperative Pain
Perioperative Effect of Music in Patients Undergoing General Anesthesia
Anxiety is a transient emotional state characterized by feelings of tension, apprehension, nervousness, fear, and heightened activation of the autonomic nervous system in response to a specific current or potential event or…
- Trial name
- EMBAG (NCT05572437)
- Testing
- Music Therapy
- Where
- Spain
- Volunteers
- 151 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Postoperative Sleep Quality, General Anesthesia
The Effects of Intravenous Anesthetics and Inhaled Anesthetics on Patients' Postoperative Sleep
Adequate sleep is necessary for physical and mental health of human being. Although surgery and anesthesia techniques have improved in resent years, postoperative sleep disturbance remains a challenging problem in surgical…
- Conditions
- Postoperative Sleep Quality, General Anesthesia, Propofol, Sevoflurane
- Trial name
- NCT04123249
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Yanchao Yang
Transcutaneous Electrical Acupoint Stimulation, Postoperative Sleep Disturbances
TEAS on Sleep Quality and POCD in Elderly Patients
Elderly patients are often considered as a high-risk population for major abdominal surgery due to reduced functional reserve and increased comorbidities.
- Conditions
- Transcutaneous Electrical Acupoint Stimulation, Postoperative Sleep Disturbances, Postoperative Cognitive Dysfunction, Elderly Patients
- Trial name
- NCT04850196
- Testing
- TEAS, control group
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Colorectal Cancer, Sleep Quality
Association of Sleep Quality and Mental Status With Early Recurrence and Prognosis of Colorectal Cancer
This is a prospective observational cohort study to explore the effects of sleep quality and mental status on early postoperative recurrence and prognosis in patients with colorectal cancer.
- Conditions
- Colorectal Cancer, Sleep Quality, Mental Status Change
- Trial name
- NCT06443996
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ma Yanlei
Desflurane, Propofol
Desflurane and Postoperative Sleep Quality in Patients Undergoing Elective Breast Surgery
This study intends to investigate the effects of desflurane on postoperative sleep quality to guide perioperative patient management.
- Conditions
- Desflurane, Propofol, Postoperative Sleep, PSQI
- Trial name
- NCT04805775
- Testing
- Desflurane Inhalation
- Where
- China
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
General Anesthesia, Thoracic Epidural Anesthesia
Postoperative Sleep Quality in Patients Undergoing Thoracic Surgery With Different Types of Anesthesia Management
We designed a study to determine whether a single dose of dexmedetomidine or thoracic epidural anesthesia combined with general anesthesia would provide hemodynamic stability, reduce stress hormone responses, inhibit inflammatory…
- Trial name
- NCT01725607
- Testing
- general anesthesia combined with dexmedetomidine infusion, general anesthesia combined with TEA
- Where
- China
- Volunteers
- 219 people
- Sponsor
- China Medical University, China
Delirium - Postoperative, Cardiac Surgery
Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients
Post-operative delirium is a common complication following cardiac surgery and is associated with increased 1 year mortality. Currently there are no drug therapies to prevent delirium.
- Conditions
- Delirium - Postoperative, Cardiac Surgery, Cardiac Surgery Subjects, Orexin Antagonist
- Trial name
- PROTEX (NCT06648681)
- Testing
- Lemborexant 5 mg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Thyroidectomy
Nurse-Led First-Night Preparation After Thyroidectomy
This study evaluates the effect of a nurse-led "first-night preparation" intervention on quality of recovery, sleep quality, and symptom management in patients undergoing elective total thyroidectomy.
- Trial name
- NCT07849946
- Testing
- Nurse-Led First-Night Preparation Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Volkan Gokmen
Pain, Postoperative, Shoulder Pain
Comparing Mindfulness-based Breath Training and Heart Rate Variability Biofeedback for Shoulder Surgery Patients in the Postoperative Pain.
Although shoulder surgeries can effectively relieve pain intensity and restore shoulder function, some patients reported persistent post-operative pain at the 6-month post-surgery follow-up visit.
- Trial name
- NCT05917262
- Testing
- Mindfulness-based breathing, HRV biofeedback, cognitive-behavioral pain psychoeducation
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Low Anterior Resection Syndrome, Rectal Cancer Surgery
Transanal Irrigation for Low Anterior Resection Syndrome
The preservation surgery of the anal sphincter muscle has become the standard procedure in the treatment of rectal cancer and, thanks to advancements in surgical techniques, can now be performed for tumors located closer to the…
- Conditions
- Low Anterior Resection Syndrome, Rectal Cancer Surgery, Insomnia
- Trial name
- TraLARS (NCT06796296)
- Testing
- Transanal Irrigation (TAI)
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital