Clinical trials: Postoperative Swelling
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Shoulder Arthroscopy, Endotracheal Tube Cuff Pressure
Irrigation Fluid Volume, Tube Cuff Pressure, and Neck Swelling During Shoulder Arthroscopy
During shoulder arthroscopy, fluid is pumped into the shoulder to help the surgeon see inside the joint. Some of this fluid can move into the tissues around the shoulder and neck and cause swelling.
- Conditions
- Shoulder Arthroscopy, Endotracheal Tube Cuff Pressure, Neck Soft Tissue Edema
- Trial name
- NCT07852702
- Testing
- Elective Shoulder Arthroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Osteoarthritis (OA) of the Hip
TED Stocking vs. Reparel Garment After Hip Replacement
This randomized, prospective study compares the effectiveness of a novel bioactive garment (Reparel Leg Sleeve) versus standard TED compression stockings in reducing postoperative leg swelling, pain, and deep vein thrombosis…
- Trial name
- NCT07246200
- Testing
- Reparel Bioactive Sleeve, TED Stocking
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Reparel
Impacted Third Molar Tooth, Postoperative Pain Control
Oral Bromelain After Bilateral Mandibular Third Molar Surgery
The goal of this clinical trial is to learn whether oral bromelain, a pineapple-derived enzyme supplement, reduces facial swelling, limited mouth opening (trismus), and pain after surgical removal of impacted lower wisdom teeth…
- Conditions
- Impacted Third Molar Tooth, Postoperative Pain Control, Trismus, Postoperative Swelling
- Trial name
- NCT07894913
- Testing
- Bromelain, Standard postoperative medication
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Kent University
Breast Edema, Breast Lymphedema
The BEACON Trial: Diagnostic Tools for Breast Lymphedema After Treatment for Breast Cancer
The goal of this observational study is to learn if participants agree to take part in the study, if the methods we are using for the study are feasible for the participants and the researchers, and to study how well two tools…
- Conditions
- Breast Edema, Breast Lymphedema, Lymphedema, Breast Cancer, Lymphedema
- Trial name
- BEACON (NCT06900023)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Facial Injuries, Pain
Topical Dexamethasone/Diclofenac Hydrogel for Postoperative Pain and Swelling in Facial Soft Tissue Injuries
This randomized, controlled clinical trial will evaluate the clinical effects of a topical thermoresponsive hydrogel containing dexamethasone sodium phosphate and diclofenac sodium on postoperative pain and facial swelling in…
- Conditions
- Facial Injuries, Pain, Swelling
- Trial name
- NCT07853664
- Testing
- Poloxmer F-127 Hydrogel with Dexamethasone/Diclofenac
- Where
- Yemen
- Volunteers
- 52 people
- Sponsor
- Thamar University
Edema
Effect of Compression Therapy on Postoperative Swelling and Pain After Total Knee Arthroplasty
The number of severely obese patients who has knee replacement surgery is rising. Obesity increases the risk of the postoperative swelling.
- Trial name
- NCT03490409
- Testing
- Thigh compression stocking
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Naestved Hospital
Post-operative Edema, Steroid Use
Prospective Evaluation of Perioperative Steroid Dosing on Postsurgical Edema in Orthognathic Surgery
The current standard of care at the Oral and Maxillofacial Department at the CDHA is the use of one gram of methylprednisolone administered intravenously prior to orthognathic surgery. This is largely based on the work of Habal.
- Trial name
- NCT03190642
- Testing
- Methylprednisolone
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jean Charles Doucet
Pain (Visceral, Somatic, or Neuropathic)
Postoperative Pain and Swelling After Flap vsFlapless Technique For Mandibular Third Molar Surgery
This randomized controlled trial evaluates postoperative pain and facial swelling following surgical removal of partially impacted mandibular third molars using flap versus flapless techniques.
- Trial name
- NCT07247929
- Testing
- flap technqiue for mandibular third molar extraction Arm A, flapless technquie arm b
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Impacted Mandibular Third Molar Extraction
Effect of Titanium-Prepared Platelet-Rich Fibrin and Low-Level Laser Therapy on Postoperative Morbidity After Mandibular Third Molar Surgery
This randomized double-blind clinical trial aims to evaluate the effects of titanium-prepared platelet-rich fibrin (T-PRF), low-level laser therapy (LLLT), and their combination on postoperative outcomes following surgical…
- Trial name
- NCT07748585
- Testing
- Titanium-Prepared Platelet-Rich Fibrin (T-PRF), Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cyprus Health and Social Sciences University
Impacted Third Molar Tooth
Effects of Polyvinylpyrrolidone Iodine on Postoperative Trismus and Swelling During Impacted Third Molar Surgery
The aim of the present study was to evaluate the effects of different concentrations of povidone iodine (PVP-I) on postoperative swelling and trismus when used as a coolant and irrigation solution during the surgical removal of…
- Trial name
- NCT03894722
- Testing
- Control, 0.5% concentration of PVP-I, 1 % concentration of PVP-I
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cansu Gül Koca
Intraoperative Bleeding, Postoperative Edema
Prevention of Intraoperative Bleeding and Postoperative Swelling in Orthognathic Surgery Through the Use of Tranexamic Acid
Purpose of the study: To evaluate the effect of tranexamic acid (TXA) of intraoperative blood loss in patients subjected to bi-maxillary orthognathic surgery To evaluate the potential effect of TXA on fibrin structure To evaluate…
- Trial name
- TXA2014-15 (NCT02229292)
- Testing
- Tranexamic Acid, Saline
- Where
- Denmark
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Breast Cancer Lymphedema
Radial Shock Wave Treatment Alongside Decongestive Care for Arm Swelling After Breast Cancer
Arm swelling can persist after breast cancer treatment and may interfere with comfort, movement, and everyday activities. Decongestive care combines several approaches to manage this swelling.
- Trial name
- NCT07862296
- Testing
- Complex decongestive therapy, Radial extracorporeal shock wave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Selcuk University
Post Operative Pain
Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars
1. To compare the postoperative pain between the patients who receive the systemic enzyme therapy and patients in the control group in the third and seventh day. 2.
- Trial name
- NCT05681312
- Testing
- systemic proteolytic enzyme (Tibrolin), Amoxicillin 500mg+metronidazole 500mg+ doliprane 100mg
- Where
- Iraq
- Volunteers
- 55 people
- Sponsor
- University of Baghdad
Abdomen Hernia
The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR
Randomized controlled trial to compare SSO's in abdominal wall reconstruction patients using Prevena, Prineo, and traditional incisional dressings.
- Trial name
- NCT04906408
- Testing
- Prevena, Prineo, Traditional
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Post-operative Inflammation Post-operative Pain Post-operative Swelling (Edema)
Efficacy of Oral Serratiopaptidase Vs Dexamethasone on Post-Operative Inflammation After Exodontia. An Experience at Tertiary Care Hospital Karachi Pakistan.
Background and Rationale Exodontia, commonly referred to as tooth extraction, is one of the frequently performed procedures in dental and oral surgical practice.
- Trial name
- EOSVDPIAEAETCH (NCT07785596)
- Testing
- Arm 1:Serratiopeptidase Arm 2: Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Kharadar General Hospital
Postoperative Swelling After TKA, Postoperative Pain After Tka
Postoperative Cryocuff vs. Conventional Icepack in TKA - What is More Effective in Reducing Pain and Swelling?
Topic/Disease Pattern Postoperative pain and swelling management after knee prosthesis implantation using cryotherapy Objective To determine possible differences in postoperative swelling and pain following primary total knee…
- Trial name
- NCT07627854
- Testing
- cryo cuff treatment, postoperative cooling with conventional ice pack
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Prof. Dr. med. Andreas Halder
Blood Loss
Fibrin Sealant in Bilateral Simultaneous Total Knee Arthroplasty With Focus on Blood Loss, Pain, Swelling and Strength
The purpose of this study is to measure the effect of fibrin sealant on reducing blood loss, pain and swelling when operated for bilateral total knee arthroplasty.
- Trial name
- NCT01472913
- Testing
- Fibrin sealant, Saline water
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Pain, Postoperative
Postoperative Course Following Wisdom Tooth Surgery
The purpose of this study is to determine how quality of life changes after surgical removal of wisdom teeth
- Trial name
- NCT00921479
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Ullevaal University Hospital
Root End Resection, Periapical Lesion
Effect of Local Use of Non-steroidal Anti-inflammatory Agent (Diclofenac Sodium) With and Without Hyaluronidase on Post-surgical Pain and Swelling
The goal of this clinical trial is to evaluate whether locally applied diclofenac sodium, with or without hyaluronidase, can reduce post-surgical pain and swelling in adult male and female patients (18 years or older) with…
- Conditions
- Root End Resection, Periapical Lesion, Single Rooted Teeth
- Trial name
- NCT07101016
- Testing
- Diclofenac Sodium Gel
- Volunteers
- 44 people
- Sponsor
- Mariam Hesham Mahmoud Abdelfattah Eissa