Clinical trials: Postoperative Visceral Pain
Postoperative Pain
Preventive Analgesia With Anrikefon in Laparoscopic Cholecystectomy
This study will determine the optimal timing for Anrikefon administration. It will also assess the quality of patient recovery. Laparoscopic cholecystectomy (LC) is a routine surgical procedure.
- Trial name
- ANIPAP (NCT07566663)
- Testing
- Anrikefon for Preventive Analgesia, Anrikefon for bridging analgesia
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Xuanwu Hospital, Beijing
Visceral Pain, Postoperative
The Visceral Analgesic Effect of Erector Spinae Plane Block in Laparoscopic Cholecystectomy
The purpose of this study was to investigate the effectiveness of erector spinae plane block on postoperative visceral pain in laparoscopic cholecystectomy (LLC).
- Trial name
- NCT03767816
- Testing
- Ultrasound guided Rectus sheath block, Ultrasound erector spinae plane block
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Colonoscopy
Effect of Butorphanol on Colonoscopy for Patients With Postoperative Visceral Pain
The total incidence of abdominal pain after colonoscopy is almost 50%. Butorphanol is a mixed opioid receptor agonist-antagonist, which has strong sedative and analgesic effects.
- Trial name
- NCT04477733
- Testing
- Butorphanol Injection, Saline
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Beijing Tiantan Hospital
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic)
Post Operative Pain and Vagal Stimulation
Anorectal surgery is a type of surgery that can cause anal pain, particularly in the context of hemorrhoid surgery or anal fissure surgery. Generally, the period of discomfort related to the pain lasts about two weeks.
- Conditions
- Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic), Vagal Nerve Stimulation
- Trial name
- VAGANAL (NCT07659314)
- Testing
- Experimental arm, Control arm
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Postoperative Pain
Effect of Visceral and Parietal Peritoneum Suturation on Postoperative Vital Signs
In this study the investigators want to asses the effect of peritonisation at c-section on postoperative vital signs which was thought to be an indirect finding secondary to increased sympathetic activity originated from pain…
- Trial name
- NCT02581293
- Testing
- Group 1: Only visceral peritoneum will be closed, Group 2 : Only parietal peritoneum will be closed, Group 3 : Both of them will be closed
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Pain (Visceral, Somatic, or Neuropathic)
Postoperative Pain and Swelling After Flap vsFlapless Technique For Mandibular Third Molar Surgery
This randomized controlled trial evaluates postoperative pain and facial swelling following surgical removal of partially impacted mandibular third molars using flap versus flapless techniques.
- Trial name
- NCT07247929
- Testing
- flap technqiue for mandibular third molar extraction Arm A, flapless technquie arm b
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Pain, Postoperative, Nausea, Postoperative
Intraoperative Autonomic Neural Blockade
The duration of the effect of autonomic neural blockade (ANB) is the most critical limitation for successful clinical application. The analgesic effect using only 0.5% bupivacaine may wear off after 12 to 18 hours.
- Conditions
- Pain, Postoperative, Nausea, Postoperative, Vomiting, Postoperative, Analgesia
- Trial name
- ANB (NCT06137924)
- Testing
- Local anesthetic injection Bupivacaine plus dexamethasone, Local anesthetic injection bupivacainde plus dexamethasone plus a colloid, Local anesthetic injection bupivacaine plus clonidine
- Volunteers
- 150 people
- Sponsor
- Universidad Simón Bolívar
Postoperative Pain, Postoperative Nausea
Autonomic Neural Field Block for Visceral Pain in Minimally Invasive Left-Sided Colectomy
Effective postoperative pain control is a core component of enhanced recovery after surgery (ERAS) pathways in colorectal surgery; however, postoperative pain following minimally invasive left-sided colectomy remains a persistent…
- Conditions
- Postoperative Pain, Postoperative Nausea, Opioid Use
- Trial name
- ANfiELD (NCT07351994)
- Testing
- Autonomic Neural Field Block
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Antonio Caycedo, MD
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia After Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07246785
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University First Hospital
Acute Pain
Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery
The purpose of this study is to determine the effectiveness and safety of single intravenous doses of the kappa opioid agonist CR845 in relieving pain in patients following laparoscopic-assisted hysterectomy surgery.
- Trial name
- NCT00877799
- Testing
- CR845
- Where
- 12 sites in United States
- Volunteers
- 114 people
- Sponsor
- Cara Therapeutics, Inc.
Pain, Acute Post-Operative, Nausea and Vomiting, Postoperative
Catheter Redosing of Autonomic Neural Blockade After Sleeve Gastrectomy
Postoperative visceral pain and autonomic symptoms after laparoscopic sleeve gastrectomy may reappear earlier in selected high-risk patients despite standard intraoperative autonomic neural blockade (ANB).
- Trial name
- NCT07655908
- Testing
- Bupivacaine 0.5% and Dexamethasone via Temporary Catheter
- Volunteers
- 30 people
- Sponsor
- Universidad Simón Bolívar
Postoperative Nausea and Vomiting, Postoperative Pain After Laparoscopic Sleeve Gastrectomy
Paragastric Block for Pain and PONV in Sleeve Gastrectomy
This single-center, prospective, randomized, double-blind controlled trial aims to evaluate the effects of intraoperative paragastric block (PGBLOCK) on early postoperative visceral pain, postoperative nausea and vomiting (PONV)…
- Trial name
- BLOCK-SG (NCT07274215)
- Testing
- Bupivacaine 0.5%, Isotonic Saline (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Umraniye Education and Research Hospital
Pain
From ACute To Chronic Postoperative Pain in Patients for Elective Cholecystectomy
Chronic Pain is a wellknown complication after cholecystectomy. Intensity of the pain in the first week after the operation is a predictive factor for the development of chronic pain, but it is unknown whether the risk is more…
- Trial name
- FACTS1 (NCT01553253)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Preemptive Peripheral Nerve Block, Pain, Postoperative
Preemptive Analgesic Effects of Rectus Sheath Block in Laparoscopic Cholecystectomy Patients
The purpose of this study was to investigate the effectiveness of preemptive effect of rectus sheath block (RSB) and intercostal nerve block (ICNB) on postoperative visceral pain in laparoscopic cholecystectomy (LLC).
- Conditions
- Preemptive Peripheral Nerve Block, Pain, Postoperative, Acute Pain
- Trial name
- NCT03413280
- Testing
- Ultrasound guided Rectus sheath block, Intercostal nerve block
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Visceral Pain
Effect of TEAS Combined With Oxycodone on Postoperative Visceral Pain in Gynecologic Laparoscopic Patients
To investigate the effect and feasibility of percutaneous acupoint stimulation combined with oxycodone on postoperative visceral pain in laparoscopic patients, and provided a clinical basis for optimizing perioperative pain…
- Trial name
- NCT06517069
- Testing
- TEAS, Oxycodone
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Postoperative Visceral Pain
Development and Validation of a Risk Prediction Model for Postoperative Visceral Pain in Abdominal Surgery Patients
This study aims to investigate the factors influencing the risk of postoperative visceral pain in patients undergoing abdominal surgery.
- Trial name
- NCT07048782
- Testing
- Observational assessment of clinical outcomes
- Where
- China
- Volunteers
- 1,135 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Pain Postoperative, Postoperative Recovery
Application of Transcutaneous Electrical Acupoint Stimulation in Laparoscopic Cholecystectomy
To explore the application of transcutaneous electrical acupoint stimulation combined with transverse abdominis plane block in Laparoscopic cholecystectomy, in order to reduce postoperative pain and promote postoperative recovery.
- Trial name
- NCT05936918
- Testing
- Transcutaneous electrical acupoint stimulatios, Bilateral transverse abdominal plane block
- Volunteers
- 120 people
- Sponsor
- Yangzhou University
Visceral Pain
Paragastric Neural Blockade and Laparoscopic Assisted Transversus Abdominis Plane Block on Visceral Pain After Surgery
after laparoscopic bariatric surgery, visceral pain (VP) remains a significant issue. VP causes autonomic symptoms, such as nausea and vomiting, and does not respond to conventional pain management methods that target incisional…
- Trial name
- NCT06973122
- Testing
- combined paragastric autonomic neural blockade and laparoscopic assisted transversus abdominis plane block, laparoscopic assisted transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 127 people
- Sponsor
- Alexandria University
Postsurgical Pain, Abdominal Pain
The Analgesic Efficacy of Δ9-THC (Namisol®) in Patients With Persistent Postsurgical Abdominal Pain
Persistent postsurgical abdominal pain (PPAP) is a very difficult to treat pain. This pain can persist for months or even years and significantly diminishes quality of life.
- Conditions
- Postsurgical Pain, Abdominal Pain, Chronic Pain
- Trial name
- NCT01562483
- Testing
- Tetrahydrocannabinol
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Radboud University Medical Center