Clinical trials: Postpartum Anemia
Postpartum Hemorrhage, Uterine Atony
Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage
The objective of the study is to demonstrate whether cooling the uterine smooth muscle during cesarean section (following delivery of the fetus) will promote better uterine contraction and involution resulting in lower blood…
- Trial name
- NCT02229513
- Testing
- Uterine Cooling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Cesarean Section Complications
Association of Placenta Removal Method and Postpartum Leucocytosis
Cesarean delivery is one of the most common major abdominal operation in women worldwide. The incidence of postpartum infection has been estimated to be 1-4% after vaginal delivery and 10-20% after Cesarean delivery.
- Trial name
- NCT04323241
- Testing
- Controlled cord traction
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Anemia
Well Being of Obstetric Patients on Minimal Blood Transfusions
Postpartum haemorrhage (PPH) is one of the top five causes of maternal mortality in developed and developing countries. The most important treatment of PPH is red blood cell (RBC) transfusion.
- Trial name
- WOMB (NCT00335023)
- Testing
- Red blood cell transfusion
- Where
- Netherlands
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sanquin Research & Blood Bank Divisions
Anemia
Iron Supplementation Among Low-Income Postpartum Women
Anemia is common among low-income women after they have given birth. Anemia, or low hemoglobin in the blood cells, is usually caused by not having enough iron. Blood cells usually carry oxygen to other parts of the body.
- Trial name
- NCT00207610
- Testing
- Daily iron supplements of 65 mg a day for 3 months, Universal anemia screening and treatment, Selective anemia screening and treatment
- Where
- United States
- Volunteers
- 959 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Nutritional Anemia in Mothers., Nutritional Anemia in Infants.
Vitamin B12 Supplementation During Pregnancy
Nutritional anemia is a major public health problem among children and women in developing countries. Despite ongoing national program of supplementing pregnant women with iron-folate, prevalence of anemia is 39% among pregnant…
- Trial name
- NCT01795131
- Testing
- Vitamin B12
- Where
- Bangladesh
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pregnancy; Fetomaternal Hemorrhage
Clinical Efficacy of Postpartum Immunization of Rh and Coombs Negative Women With Sensitization Risk.
This a open, prospective, multicenter, single-arm, phase III study for clinical assessment of anti-Rh immunoglobulin (KamRho-D®) in Rh and Coombs negative women with risk sensitization.
- Trial name
- NCT01666249
- Testing
- Immunoglobulin Anti-RhD
- Where
- 5 sites in Brazil
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Azidus Brasil
Bloodloss in Pregnancy
Evaluation of Peripartum Blood Loss and Postpartum Anaemia in Macrosomia & Gemini
Anaemia in pregnant women occurs at a haemoglobin (Hb) concentration <11 g/dL and treatment is essential to prevent increased maternal morbidity, fetal morbidity and mortality.
- Trial name
- NCT06201910
- Testing
- Observation of Blood loss
- Where
- 2 sites in Germany
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- Goethe University
Anemia Complicating Pregnancy, Anemia Complicating Childbirth
Survey Tool for Screening of Anemia in Women Before Pregnancy
The goal of this observational and cross-sectional study is to develop and validate a survey that can be used to identify anemia, and its severity, among pre-pregnant women allowing for the timely implementation of focused public…
- Conditions
- Anemia Complicating Pregnancy, Anemia Complicating Childbirth, Anemia Complicating the Puerperium
- Trial name
- PREPSA (NCT05832840)
- Where
- India
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Postpartum Anemia
Effect of Ejiao Compound in the Treatment of Postpartum Anemia of Qi-blood Deficiency Syndrome
The prevalence of postpartum anemia is a great threat for maternal and infant health without timely and effective treatment. Oral iron therapy has been used for centuries as a treatment of anemia, however, it is noteworthy that…
- Trial name
- NCT02656225
- Testing
- Ejiao compound, Niferex
- Where
- China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
Postpartum Depression
Postpartum Anemia and Postpartum Depression
Postpartum anemia (PPA) and Postpartum depression (PPD) are common afflictions affecting women after childbirth. Both disorders have a significant impact on women's health and functional status.
- Trial name
- PPADS (NCT00782912)
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Episiotomy Wound, Anemia
Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail
The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.
- Conditions
- Episiotomy Wound, Anemia, Early Postpartum Hemorrhage, Hemoglobin
- Trial name
- NCT05448456
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Hypothermia, Hemorrhage, Postpartum
Complications Associated With Intraoperative Hypothermia.
Maintaining intraoperative normothermia and temperature measurement is a marker of quality of care. We know that intraoperative hypothermia is associated with an increased risk of cardiovascular events, infection of the surgical…
- Conditions
- Hypothermia, Hemorrhage, Postpartum, Infection Surgical Wound, Transfusion-dependent Anemia
- Trial name
- NCT05203016
- Testing
- Hipotermia/Normotermia
- Where
- Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Postpartum Period
Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care
Postpartum hemorrhage and anemia are considered a major health concern due to their impact on maternal morbidity and mortality, quality of life, and maternal cognitive and emotional functioning after delivery, which are…
- Trial name
- NCT06963047
- Testing
- Ultrasound, Standard care
- Where
- Israel
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Anemia, Iron Deficiency, Delivery Complication
Intravenous Iron vs. Oral Iron Supplementation for Postpartum Anemia
This trial will be a comparative pragmatic open label feasibility randomized controlled trial of oral daily versus IV iron in anemic postpartum patients.
- Trial name
- IVIRONMAN (NCT05047211)
- Testing
- Ferrous sulfate, Iron dextran
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Postpartum Hemorrhage
Misoprostol for Preventing Postpartum Hemorrhage
This hospital-based, multicenter, randomized, placebo-controlled trial will assess the effects of misoprostol as part of active management of the third stage of labor on postpartum blood loss, complications, and side effects.
- Trial name
- NCT00124540
- Testing
- misoprostol
- Where
- 5 sites in Nigeria, South Africa and 1 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Antepartum Hemorrhage, Postpartum Hemorrhage
Strengthening Maternal Neonatal and Child Health Services in a Rural District of Pakistan
The Maternal Neonatal and Child health indicators in District Dadu of Pakistan portrays a dismal pictures and after the floods of 2010-2011 the health infrastructure of this district was badly affected.
- Conditions
- Antepartum Hemorrhage, Postpartum Hemorrhage, Anemia, Eclampsia
- Trial name
- SRC (NCT02797353)
- Testing
- Maternal Neonatal and Child Health Interventions
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Anemia, Ferritin
Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants
In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan.
- Conditions
- Anemia, Ferritin, Complications, Hemorrhage
- Trial name
- NCT01081977
- Testing
- Early Cord Clamping, Delayed Cord Clamping
- Where
- Pakistan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Atypical Hemolytic Uremic Syndrome, Pregnancy
Eculizumab Use in the Postpartum Period for the Treatment of Pregnancy Associated aHUS: A Case Series
Eculizumab is a humanized monoclonal IgG antibody against protein C5 that works to inhibit the activation of the terminal complement cascade.
- Trial name
- NCT03574506
- Where
- Colombia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia
Iron Deficiency Anemia of Pregnancy, Iron-deficiency
Non-invasive Detection of Iron Deficiency in Obstetrics
Validation of non-invasive measurement of zinc protoporphyrin for detection of iron deficiency in pregnancy. In addition, the impact of iron deficiency on the incidence of postpartum depression, restless legs syndrome, obstetric…
- Conditions
- Iron Deficiency Anemia of Pregnancy, Iron-deficiency, Restless Leg Syndrome in Pregnancy, Restless Leg Syndrome Due to Iron Deficiency Anaemia
- Trial name
- PICCOLINO (NCT07083492)
- Testing
- non-invasive measurement of zink protoporphyrin
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Iron Deficiency Anemia
Iron Status, Maternal Depressive Symptoms, and Mother-child Interactions
This study aims to examine the relation between iron status and maternal-child interactions as well as maternal depressive symptoms in mothers from central Pennsylvania.
- Trial name
- IDinteract (NCT03944733)
- Testing
- Iron, Gelatin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Penn State University