Clinical trials: Postpartum Hemorrhage,
Post Partum Hemorrhage, Anemia of Pregnancy
Hemoglobin Testing in Pregnant Patients
The project is a prospective observational study aimed to assess and to validate the use of point-of-care hemoglobin testing in pregnancy.
- Trial name
- AnemiaPOC (NCT05977686)
- Testing
- Masimo Root Radical 7 Pulse CO-Oximeter, HemoCue Hb 801
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Coagulation Defect; Puerperal, Post Partum Hemorrhage
Bedside Assessment of Coagulation in Post-partum Hemorrhage by Thromboelastography (TEG ®6S)
Postpartum hemorrhage (PPH) is one of the leading causes of maternal deaths. Its prognosis is directly influenced by the early diagnosis and treatment of the associated coagulopathy.
- Conditions
- Coagulation Defect; Puerperal, Post Partum Hemorrhage, Blood Protein Disorders, Pregnancy Hemorrhage
- Trial name
- HPPTEG6S (NCT03592303)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postpartum Hemorrhage
Uterine Massage After Vaginal Delivery
The participants will be randomized into an oxytocin plus uterine massage group and an oxytocin-only group in the third stage of the labor.
- Trial name
- NCT03858569
- Testing
- active management of third stage of labor
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Post Partum Hemorrhage
Feasibility Clinical Investigation Using the InPress Device for the Treatment of Postpartum Hemorrhage
Feasibility trial of the InPress Device to treat postpartum hemorrhage (PPH).
- Trial name
- NCT04364386
- Testing
- InPress Device
- Where
- 2 sites in Indonesia
- Volunteers
- 10 people
- Sponsor
- Alydia Health
Post Partum Hemorrhage
Predictability of Thromboelastography Parameters in Severe Post Partum Hemorrhage
The aim of the study is to determine if thromboelastography parameters can be predictive of severe post partum hemorrhage.
- Trial name
- NCT03449420
- Testing
- thromboelastography
- Volunteers
- 100 people
- Sponsor
- Hôpital Armand Trousseau
Postpartum Hemorrhage
Prevention of Postpartum Hemorrhage With TXA
Hemorrhage remains the leading cause of maternal death worldwide. Tranexamic acid has been shown to reduce rates of hemorrhage when given prophylactically prior to cesarean delivery.
- Trial name
- TXA (NCT03326596)
- Testing
- Tranexamic Acid 1000 mg/10ml normal saline infusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Postpartum Hemorrhage
Accuracy of Blood Loss Estimation After Vaginal Delivery
Post-partum hemorrhage (PPH) is defined as blood loss greater than 500 mL after vaginal delivery. Delayed diagnosis of PPH is a major cause of maternal morbidity and mortality.
- Trial name
- NCT00462839
- Testing
- blood loss estimation
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Post Partum Hemorrhage, Blood Loss
Estimating Blood Loss Using TritonTM in Vaginal Deliveries: A Validation Trial
This study will be a prospective cohort study. Patients who meet criteria for inclusion in the study will be approached for participation at same day of admission.
- Conditions
- Post Partum Hemorrhage, Blood Loss, Vaginal Bleeding, Vaginal Delivery
- Trial name
- ELUSIVE (NCT04277962)
- Testing
- Triton L and D system for estimation of blood loss at time of vaginal delivery
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Teaching Innovation, Midwifery Students Education
Flipped Learning in PPH Education: Impact on Midwifery Students' Knowledge, Skills, Self-Efficacy, and Satisfaction
Maternal death refers to a woman's death due to direct or indirect causes during pregnancy, childbirth, or within 42 days postpartum.
- Conditions
- Teaching Innovation, Midwifery Students Education, Postpartum Hemorrhage, Flipped Classroom Model in Teaching
- Trial name
- NCT06861296
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Post Partum Hemorrhage, Cesarean Section Complications
Oxytocin Pharmacokinetics and Pharmacodynamics
Oxytocin is the first-line drug to promote contraction of the uterus and prevent atony immediately after delivery. Nonetheless, unpredictable uterine atony refractory to oxytocin affects roughly 250,000 parturients annually in…
- Conditions
- Post Partum Hemorrhage, Cesarean Section Complications, Blood Loss
- Trial name
- NCT05488457
- Testing
- deuterated oxytocin (d5OT)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Postpartum Hemorrhage, Pain
Do Elastic Abdominal Binders Reduce Post Operative Pain and Blood Loss?
This is a pilot study investigating the use of abdominal binders after cesarean sections. The researchers are testing whether elastic abdominal binders improve postoperative pain control and reduce postoperative blood loss.
- Trial name
- NCT01786330
- Testing
- Procare abdominal binder, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zachary Kuhlmann, DO
Anemia, Ferritin
Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants
In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan.
- Conditions
- Anemia, Ferritin, Complications, Hemorrhage
- Trial name
- NCT01081977
- Testing
- Early Cord Clamping, Delayed Cord Clamping
- Where
- Pakistan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Post Partum Hemorrhage
The Effect of Preoperative and Post Operative Misoprostol Administration on Intraoperative Blood Loss and Postpartum Hemorrhage in CS
Patients will be divided into two groups 100 patients will receive routine ecbolics (for example oxytocin) after delivery of baby The 100 patients will receive routine ecbolics (for example oxytocin) after delivery of baby plus…
- Trial name
- NCT03680339
- Testing
- cesarean section, Misoprostol, Oxytocin
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Postpartum Haemorrhage
Bimanual Uterine Compression to Reduce Blood Loss and Prevent Postpartum Haemorrhage After Vaginal Delivery
the investigators aim to compare bimanual uterine compression immediately after delivery of the placenta for 5 minutes versus no intervention for the prevention of postpartum hemorrhage in Women at high risk for primary atonic…
- Trial name
- NCT02136719
- Testing
- bimanual uterine compression
- Where
- Egypt
- Volunteers
- 520 people
- Sponsor
- Benha University
Postpartum Hemorrhage, Delivery Complication
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is the global leading cause of maternal death, with 20-30% of maternal deaths in Thailand linked to hemorrhage.
- Conditions
- Postpartum Hemorrhage, Delivery Complication, Cesarean Section Complications, Perinatal Problems
- Trial name
- NCT07278037
- Testing
- Tranexamic acid
- Where
- Thailand
- Volunteers
- 648 people
- Sponsor
- Mahidol University
Postpartum Hemorrhage
Postpartum Oxygen Inhalation for the Treatment of Postpartum Haemorrhage
In the aetiology of postpartum uterine atony, hypoxia is considered an important factor although some suggest that peripheral oxygen saturation is not influenced by oxygen inhalation in women during the first and second stages of…
- Trial name
- NCT01180192
- Testing
- oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Postpartum Bleeding, Oxytocin
Comparing Intra-Umbilical Versus Intravenous Oxytocin in Women During the Third Stage of Labor for Reducing Blood Loss
The goal of this clinical trial is to determine whether giving oxytocin through the umbilical cord is more effective than giving it through a vein in reducing blood loss during the third stage of labor.
- Conditions
- Postpartum Bleeding, Oxytocin, Third Stage of Labour
- Trial name
- NCT07566455
- Testing
- Oxytocin after delivery, Intraumbilical oxytocin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Postpartum Hemorrhage, Twin
Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy
Postpartum hemorrhage (PPH) due to uterine atony is a major cause of maternal morbidity and mortality. Uterotonic drugs are used to improve the muscle tone of the uterus after birth and these are effective at reducing the…
- Trial name
- NCT04025658
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Placenta, Retained, Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage
Management of Large Retained Products of Conception (> 4 cm): Need for an Standardized Procedure.
Collection of relevant data form patients who were treated in the Ghent University Hospital in the context of a placental remnant lager than 4 cm, performing statistical analyzes on the collected data, reviewing the literature on…
- Conditions
- Placenta, Retained, Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage, Placenta; Retention, Fragments, Complicating Puerperium (Delayed Hemorrhage), Pregnancy Related
- Trial name
- NCT04720885
- Testing
- kind of surgery
- Where
- Belgium
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent