Clinical trials: Postpartum Hemorrhage
Postpartum Haemorrhage
Bimanual Uterine Compression to Reduce Blood Loss and Prevent Postpartum Haemorrhage After Vaginal Delivery
the investigators aim to compare bimanual uterine compression immediately after delivery of the placenta for 5 minutes versus no intervention for the prevention of postpartum hemorrhage in Women at high risk for primary atonic…
- Trial name
- NCT02136719
- Testing
- bimanual uterine compression
- Where
- Egypt
- Volunteers
- 520 people
- Sponsor
- Benha University
Postpartum Hemorrhage
Investigating the Association of Shock Index and Hemoglobin Variation With Postpartum Hemorrhage After Vaginal Deliveries
Postpartum hemorrhage (PPH) is a leading cause of maternal mortality and morbidity, and is most commonly caused by poor uterine tone after delivery of the baby and placenta.
- Trial name
- NCT03432767
- Testing
- Non-invasive hemoglobin monitor
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Atonic PPH
Protocols for Prevention of PPH During CS in High Risk Group
PPH is one of the most leading causes of maternal mortality,. It means loss of 500 ml blood after vaginal delivery and 1000 ml blood after cesarean delivery. Although it's preventable it represents about 27%of maternal deaths.
- Trial name
- NCT05099575
- Testing
- Syntocinon, papal, misotac
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postpartum Hemorrhage
Does Cold Saline Used to Inflate a Balloon Tamponade Catheter More Significantly Reduce Blood Loss From Postpartum Hemorrhage Than Room Temperature Saline?
To determine if a balloon tamponade catheter filled with cold saline is more effective than a catheter filled with room temperature saline in controlling post partum hemorrhage.
- Trial name
- NCT02735733
- Testing
- Cold Bakri Balloon
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Post Partum Hemorrhage
Cervical Traction vs. Active Management of 3rd Stage of Labor
306 patients will be divided randomly in to 2 GROUPS: control group: 153 patients will receive Oxytocin 10 IU I.V shot administered at the time of delivery of the anterior shoulder of the baby for both groups in prevention of…
- Trial name
- NCT04747015
- Testing
- Oxytocin, cervical traction
- Where
- Egypt
- Volunteers
- 306 people
- Sponsor
- Cairo University
Postpartum Hemorrhage (PPH), Placental Dysfunction
Risk Factors for Postpartum Hemorrhage in Patients With Histologically Verified Placenta Accreta
This retrospective, monocentric study aims to examine risk factors for postpartum hemorrhage in women with histologically verified placenta accreta.
- Trial name
- NCT05542043
- Testing
- Data collection
- Where
- Switzerland
- Volunteers
- 2,348 people
- Sponsor
- University Hospital, Basel, Switzerland
Game-based Education
Effect of Postpartum Hemorrhage Management Education Given With Kahoot Method on Knowledge, Self-Confidence in Intervention and Motivation Levels of Midwifery Students
This study was planned to investigate the effect of postpartum hemorrhage management training given with the Kahoot method on the knowledge, self-confidence in intervention and motivation levels of midwifery students.
- Trial name
- NCT06897371
- Testing
- Games-based education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cesarean Section Complications
Tranexamic Acid for the Control of Blood Loss at Elective Cesarean Section
The aim of the study is to determine, out of two doses (a standard and a low dose) compared to placebo, the optimal and minimal dose of an intravenously administered single bolus of tranexamic acid(TA) to reduce blood loss when…
- Trial name
- NCT03710330
- Testing
- normal saline, 1gm tranexamic acid, 0.5 gm tranexamic acid
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Aswan University Hospital
Pregnancy Hemorrhage, Postpartum Hemorrhage
Implementation of the NPMS Obstetric Hemorrhage Bundle at a Tertiary Center: Utilization of the Delphi Method
The National Partnership for Maternal Safety (NPMS) developed an obstetric hemorrhage consensus bundle to provide every United States birthing facility consistent, validated practice guidelines.
- Trial name
- NCT03018119
- Testing
- Survey
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Postpartum Hemorrhage
Effectiveness, Safety and Feasibility of Auxiliary Nurse Midwives' (ANM) Use of Oxytocin in Uniject™ to Prevent Postpartum Hemorrhage in India
This cluster randomized community-based trial is designed to test the hypothesis that the intramuscular administration of 10 IU of oxytocin in Uniject™ during the third stage of labor by an Auxiliary Nurse Midwife (ANM) at births…
- Trial name
- NCT01108302
- Testing
- Oxytocin in Uniject
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Postpartum Hemorrhage
Tranexamic Acid and Ethamsylate For Preventing PPH in Patient Undergoing LSCS at High Risk For PPH
The aim of this study is to compare the effect of low dose of Tranexamic acid (1gm) and Ethamsylate (1gm) after prophylactic oxytocin administration versus placebo with prophylactic oxytocin given in the 2 minutes after child…
- Trial name
- NCT02604719
- Testing
- Tranexamic Acid and Ethamsylate
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ahmed Alanwar
Postpartum Hemorrhage
Prophylactic Amnioinfusion for Prevention of Postpartum Hemorrhage
The purpose of this study is to decrease the likelihood of composite postpartum hemorrhage (PPH) morbidity, which consists of i) Estimated or quantified blood loss of 1,500 mL or more, ii) transfusion of any blood products or…
- Trial name
- PURPOSE (NCT06691945)
- Testing
- Saline delivered using an intrauterine pressure catheter (IUPC)
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- The University of Texas Health Science Center, Houston
Postpartum Hemorrhage
Active Versus Expectant Management of the Third Stage of Labor
The purpose of this study is to determine if giving oxytocin immediately after delivery causes less bleeding, transfusion needs and hastens delivery of placenta.
- Trial name
- NCT00473707
- Testing
- Active management of the third stage of labor, Expectant management of the third stage of labor, Oxytocin and gentle cord traction with fundal massage
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Postpartum Hemorrhage, Obesity
Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With BMI ≥ 40kg/m2
Postpartum hemorrhage (PPH) due to uterine atony is a major cause of maternal morbidity and mortality. Uterotonic drugs are used to improve the muscle tone of the uterus after birth, and these are effective at reducing the…
- Trial name
- NCT03957083
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Post Partum Hemorrhage
Ergometrine Versus Oxytocin in the Management of Atonic Post-partum Haemorrhage (PPH) in Women Delivered Vaginally
200 women with PPH will be randomly divided into 2 equal groups using computer generated random numbers. Group 1 will receive Ergometrine 400µgm (Methergin® Novartis, Switzerland) and group 2 will receive oxytocin 10 IU…
- Trial name
- NCT02306733
- Testing
- Ergometrine, Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University