Clinical trials: Postprandial
Glycaemia
The Effect of Hydration on Postprandial Metabolic Responses
Certain populations, such as industrial workers and endurance athletes are particularly susceptible to dehydration due to exposure to heat for long periods of time causing evaporative water loss via sweating.
- Trial name
- NCT06825962
- Testing
- Water intake, Water restriction
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Lipemia
Comparison of the Effect of MCFA and LCFA on Postprandial Appetite and Lipemia
The main objective is to investigate if foods high in coconut oil (MCFA) or palm oil (LCFA) have different impacts on postprandial blood lipid levels and appetite via a visual analog scale (VAS).
- Trial name
- NCT05539742
- Testing
- Coconut oil, Palm oil
- Where
- 2 sites in Jordan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Type 1 Diabetes, Diabetes Complications
Individualised Postprandial Glucose Responses in Type 1 Diabetes
Type 1 diabetes (T1D) is a lifelong disease which stops the body from producing insulin - an important hormone that controls blood sugar (glucose) levels.
- Conditions
- Type 1 Diabetes, Diabetes Complications, Postprandial Hyperglycemia
- Trial name
- NCT05231642
- Testing
- Nutritional Interventional
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Sunderland
Type 2 Diabetes Mellitus
A Trial to Compare Post Prandial Blood Glucose Control of BioChaperone® Combo With Humalog® Mix25 and With Simultaneous Injections of Humalog® and Lantus® in Subjects With Type 2 Diabetes
This is a two-centre, randomised, double-blind, double-dummy, 3-treatment, 3-period cross-over study using a standardised solid meal test in subjects with type 2 diabetes to investigate postprandial glucose control of…
- Trial name
- NCT02915250
- Testing
- BioChaperone® Combo, Humalog® Mix25, Humalog®
- Where
- 2 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Adocia
Healthy
Effects of Barley on Glucose Control
Lifestyle modifications that include a diet high in fibre may lower the risk of developing type 2 diabetes (CDA, 2013). In this context, the presence of soluble dietary fibre in carbohydrate rich foods has been widely recognized…
- Trial name
- NCT02367989
- Testing
- 0g barley β-glucan no fibre, 2g barley β-glucan, 4g barley β-glucan
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St. Boniface Hospital
1- Microvascular Function, 2-oxidative Stress
Acute and Short-term Chronic Effects of Galvus (Vildagliptin) in Diabetes Type 2 Obese Women
The prevalence of obesity and type 2 diabetes mellitus (T2DM) has increased progressively in the past decades, and consequently, a higher incidence of cardiovascular diseases is observed.
- Conditions
- 1- Microvascular Function, 2-oxidative Stress, 3-inflammation
- Trial name
- NCT01827280
- Testing
- Vildagliptin
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Rio de Janeiro State University
Appetite
Cereal-based Products Fortified With Legumes and Effects on Glycemic Control and Appetite Regulation
Legumes are rich source of proteins and dietary fibers which are associated with satiety and amelioration of postprandial glycemic response.
- Trial name
- NCT03974165
- Testing
- Cereal-legume product 1, Cereal-legume product 2, Cereal product
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Obesity
Calcium Over Postprandial Effects of Fatty Meal on Metabolism, Blood Pressure, Oxidative Stress, Endothelial Function.
The purpose of the study is to investigate calcium acute influence over the postprandial effects of a fatty meal on serum calcium, plasma glucose and triglycerides, blood pressure, oxidative stress, and endothelial function in…
- Trial name
- NCT02137434
- Testing
- Dietary calcium, Supplementary calcium
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Rio de Janeiro State University
Dumping Syndrome, Hypoglycemia, Reactive
Investigating the Impact of the SGLT2 Inhibitor Empagliflozin on Postprandial Hypoglycaemia After Gastric Bypass
Bariatric surgery is an effective anti-obesity treatment providing durable weight loss and profound beneficial effects on glucose metabolism.
- Trial name
- NCT05057819
- Testing
- Empagliflozin 25 MG
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypercholesterolemia
A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)
A study to evaluate the cholesterol-lowering effects of ezetimibe in participants with primary hypercholesterolemia (high cholesterol) after eating a meal that is high in cholesterol.
- Trial name
- NCT00101439
- Testing
- ezetimibe
- Volunteers
- 58 people
- Sponsor
- Organon and Co
Diet-induced Thermogenesis
Inter-Individual Variability in Early Diet-Induced Thermogenesis After a Standardized Meal
This study aims to characterize how individuals differ in their metabolic response to food intake, specifically focusing on early diet-induced thermogenesis (DIT).
- Trial name
- NCT07610759
- Testing
- Standardized Liquid Meal
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Absorption; Chemicals, Healthy Diet
Influence of Proteins on the Bioavailability of Carotenoids
A postprandial intervention study is conducted on healthy male subjects to evaluate whether the addition of proteins (why protein isolate, soy protein) can help to increase the bioavailability of carotenoids from a tomato/carrot…
- Conditions
- Absorption; Chemicals, Healthy Diet, Metabolism
- Trial name
- CAROPROT (NCT04078646)
- Testing
- Intervention with soy protein isolate, Intervention with whey protein, Intervention without protein addition
- Where
- Luxembourg
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Glycaemia
Glycaemic and Insulinaemic Responses After Consumption of FOS.
The study aims to evaluate the glycaemic and insulinaemic response of short-chain fructo-oligosaccharides (scFOS) used to replace sugars (e.g. dextrose) in foods.
- Trial name
- GLYCOFOS-cream (NCT02353403)
- Testing
- Sugar, FOS
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
IBS - Irritable Bowel Syndrome
Postprandial Lipids in IBS and Nutritional Treatment
Irritable Bowel Syndrome (IBS) is a disease that affects a large number of people. Adequate treatment is difficult, partially due to the heterogeneity of the patients and the complicated pathology in which not all mechanisms are…
- Trial name
- PLINT (NCT05016596)
- Testing
- turmeric
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Glycogen Storage Disease Type I
Use of Continuous Glucose Monitoring to Evaluate Postprandial Response to Raw Cornstarch Supplementation in Adult Glycogen Storage Disease Type I
The aim of this observational study is to evaluate the impact of raw cornstarch supplementation on postprandial glycemic response in adult patients with Glycogen Storage Disease type I (GSD I), using continuous glucose monitoring…
- Trial name
- NCT07645898
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- Federico II University
Diabetes Mellitus, Upper Respiratory Infection
Effects of URI on Diabetic Subjects Utilizing Technosphere Insulin After a Meal Challenge
Effect of upper respiratory infection (URI) on diabetic subjects with a meal challenge
- Trial name
- NCT00642681
- Testing
- Technosphere Insulin
- Where
- 24 sites in United States, Canada and 1 more
- Volunteers
- 20 people
- Sponsor
- Mannkind Corporation
Type 2 Diabetes
Cocoa/Carob Polyphenols and Postprandial Changes in Type 2 Diabetes
The aim of this is study is to evaluate the effects of a single intake of a mixture of cacao and carob (rich in high molecular weight polyphenols) in postprandial metabolism in subjects with type 2 diabetes.
- Trial name
- CACAOBA (NCT04383639)
- Testing
- No product (A)/mixture of coca and carob together with breakfast (B)/mixture of coca and carob 10 h before breakfast (C)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- National Research Council, Spain
Hyperlipoproteinemia, Metabolic Syndrome
Effect of Niacin/Laropiprant on Postprandial Lipoprotein Metabolism in Patients With Dyslipoproteinemia
The study is designed to evaluate the effect of Niacin/Laropiprant on postprandial lipoprotein metabolism, postprandial glucose metabolism, postprandial monocyte function, and postprandial biomarkers of endothelial dysfunction…
- Trial name
- NCT01239992
- Testing
- Niacin/ Laropiprant
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Blood Sugar
Comparison of the Postprandial Glycemic and Insulinemic Response of ALLSWEET When Taken Alone or When Added to Sucrose
This study will explore the postprandial glycemic response of ALLSWEET®, a non-GMO certified allulose, when consumed alone or with sucrose, compared to the consuming sucrose alone.
- Trial name
- NCT05185960
- Testing
- ALLSWEET®, ALLSWEET® and sucrose, Sucrose
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Anderson Advanced Ingredients
Type 1 Diabetes
The Effect of GLP-1 on Postprandial Glucagon Secretion Independent of The Gastric Emptying Rate
Aim: To investigate the glucagonostatic effect of glucagon-like peptide-1 (GLP-1) independent of the gastric emptying rate.
- Trial name
- ALFA-1 (NCT02584582)
- Testing
- Liraglutide, Exenatide, Liquid meal test
- Volunteers
- 10 people
- Sponsor
- Hvidovre University Hospital
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