Clinical trials: Postprandial Hypoglycemia, open to volunteers
Hypoglycemia, Hypoglycemia, Reactive
Post-Prandial Carbohydrate Metabolism in Individuals With and Without Post-Bariatric Surgery Hypoglycemia (PBH)
In this study, the investigators will determine (a) whether metabolism (secretion and turnover) of glucagon is altered in patients with PBH, (b) whether this is affected by a meal, (c) whether PBH affects the ability of the body…
- Conditions
- Hypoglycemia, Hypoglycemia, Reactive, Bariatric Surgery
- Trial name
- NCT07818707
- Testing
- Glucagon for Injection (Fresenius Kabi USA), [6,6-2H2] glucose, [13C9, 15N1]-glucagon
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Healthy
Effects of Reactive Hypoglycaemia on Cognition in Earlier or Later Chronotypes
Studies suggest a link between lower postprandial glycaemic response and better cognitive performance in children, adolescents, and young adults, though evidence remains inconclusive.
- Trial name
- GlyCoBrainI2 (NCT06941740)
- Testing
- immediate verbal memory after low glycemic index breakfast inducing no reactive hypoglycaemia, immediate verbal memory after low glycemic index breakfast causing reactive hypoglycaemia
- Where
- Germany
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Anette Buyken
Type 1 Diabetes Mellitus
The Postprandial Hypo-Avoid Study
The objective of the study is to evaluate whether pre-exercise administration of low-dose subcutaneous glucagon prevents or attenuates exercise-induced declines in plasma glucose concentration during and after moderate-intensity…
- Trial name
- NCT07427251
- Testing
- Low-Dose Glucagon, Glucose Arm
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Steno Diabetes Center Copenhagen
Hypoglycemia, Cerebral Blood Flow
External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia
This is a pilot study (small-scale study) that aims to understand more about how blood flow changes in people who have low blood sugar after bariatric surgery (post-bariatric hypoglycemia) compared to those who have had surgery…
- Trial name
- NCT07082478
- Testing
- in-ear device measuring blood flow
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Oesophageal Atresia, Dumping Syndrome
Dumping Syndrome and Esophageal Atresia
Dumping syndrome (DS) is frequent in oesophageal atresia (29%). In causing hypoglycaemia, it can be dangerous for neonates. Mechanisms of DS are actually partialy understood.
- Trial name
- DUMTORING (NCT04522193)
- Testing
- Glycemic Holter, gastric emptying scintigraphy, Holter ECG
- Where
- 2 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Lille
Postprandial Hypoglycemia
Canakinumab for the Treatment of Postprandial Hypoglycemia
The primary objective of this randomized trial is to test whether a treatment with canakinumab is superior to placebo in patients with postprandial hypoglycemia after bariatric surgery, that is if it improves health related…
- Trial name
- CanpHy (NCT05401578)
- Testing
- Canakinumab
- Where
- 2 sites in Switzerland
- Volunteers
- 56 people
- Sponsor
- University Hospital, Basel, Switzerland
Hypoglycemia Non-Diabetic, Gastric Bypass Surgery
Glucose Monitoring in Treatment of Postprandial Hypoglycemia After Gastric Bypass Surgery
The goal of this clinical trial is to learn if continuous glucose monitoring works to treat postprandial hypoglycaemia in patients who have undergone gastric bypass surgery.
- Trial name
- HypoSurge (NCT06468865)
- Testing
- Continuous glucose monitor (Dexcom® G7)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sykehuset i Vestfold HF
Postprandial Hypoglycemia, End-stage Renal Disease (ESRD)
Anakinra for the Treatment of Postprandial Hypoglycemia in a Patient With Total Gastrectomy and End-Stage Renal Disease
Post-meal low blood sugar (postprandial hypoglycemia) is a common problem after certain stomach surgeries like gastric bypass or stomach removal.
- Conditions
- Postprandial Hypoglycemia, End-stage Renal Disease (ESRD), Gastrectomy, Glucose Metabolism Disorders
- Trial name
- AnPHy-ReD (NCT07580079)
- Testing
- Anakinra (interleukin-1 receptor antagonist)
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Marc Donath