Clinical trials: Postprandial Metabolism
Cardiovascular Risk Markers, Postprandial Metabolism
Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults
The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk…
- Conditions
- Cardiovascular Risk Markers, Postprandial Metabolism, Exercise Physiology, Substrate Oxidation
- Trial name
- NCT07229963
- Testing
- Aerobic Exercise Intervention, Sprint Exercise Intervention, Sedentary Behaviour Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Postprandial Metabolism, Healthy Volunteers
Postprandial Metabolic Responses to Sustainable and Non-Sustainable Meals in Healthy Young Men
This randomized crossover study evaluated the acute postprandial metabolic and hydration responses to two standardized lunch meals differing in nutritional quality and environmental footprint in healthy young men.
- Trial name
- THERMOS-LUNCH (NCT07808736)
- Testing
- Healthy-Sustainable Test Meal, Non-Sustainable Test Meal
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Parma
Lipid Metabolism, Postprandial Inflammation
Modulating Immune Responses After Consistent Lipid Exposure
Background of the study: Enhanced immune responses can lead to chronic hyperinflammation, which contributes to the development of non-communicable diseases such as type 2 diabetes and cardiovascular disease.
- Trial name
- MIRACLE (NCT07502898)
- Testing
- Dairy-derived breakfast shake consumption, Plant-derived breakfast shake consumption
- Where
- Netherlands
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Postprandial Hypoglycemia, End-stage Renal Disease (ESRD)
Anakinra for the Treatment of Postprandial Hypoglycemia in a Patient With Total Gastrectomy and End-Stage Renal Disease
Post-meal low blood sugar (postprandial hypoglycemia) is a common problem after certain stomach surgeries like gastric bypass or stomach removal.
- Conditions
- Postprandial Hypoglycemia, End-stage Renal Disease (ESRD), Gastrectomy, Glucose Metabolism Disorders
- Trial name
- AnPHy-ReD (NCT07580079)
- Testing
- Anakinra (interleukin-1 receptor antagonist)
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Marc Donath
Postprandial Glucose Response, Insulin Response
A1-Free vs. Conventional Milk Metabolic Response Study
This study will examine how different types of milk affect blood sugar and insulin responses after eating. Specifically, the study compares milk that contains only A2 beta-casein protein (A1-free milk) to conventional milk, which…
- Conditions
- Postprandial Glucose Response, Insulin Response, Lactose Digestion, Postprandial Metabolism
- Trial name
- NCT07567443
- Testing
- Lactose-Containing A1-Free Milk, Lactose-Containing Conventional Milk, Lactose-Free A1-Free Milk With Delayed Lactose Drink
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Purdue University
Postprandial Lipid Metabolism, Type 1 Diabetes (T1D)
The TiMeD-T1D Project
The aim of the proposed study is to investigate the metabolic consequences of varying the timing of meal insulin boluses and skipping boluses altogether in individuals with type 1 diabetes.
- Trial name
- NCT07172672
- Testing
- 400 mL Fresubin Energy Drink and 100 mL heavy cream with the addition of the 18F-FTHA radiotracer
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Functional Immune Response, Postprandial Bioavailability DHA
The Effect of Algae Oil Supplements on Functional Immune Response and Bioavailability of Lipids in Blood, a Pilot Study
In this explorative study we will investigate whether two sustainable oil supplements yield equivalent results to fish oil supplements in terms of postprandial immune response, among elderly adults, after standardization of the…
- Conditions
- Functional Immune Response, Postprandial Bioavailability DHA, Fatty Acid Metabolism
- Trial name
- ALG (NCT07086573)
- Testing
- Algae oil 1, Algae oil 2, Fish oil (control)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maartje van den Belt
Fasting, Postprandial Hyperglycemia
Postprandial Metabolome and Metabolic Flexibility
Metabolic flexibility is a process in which the body can switch energy substrates in different physiological states. This flexibility plays an important role in an individual's health because losing it increases the risk of…
- Conditions
- Fasting, Postprandial Hyperglycemia, Lipid Metabolism Disorders, Glucose Metabolism Disorders
- Trial name
- NCT06878781
- Testing
- High carbohydrate challenge, High lipid challenge, High proteinchallenge
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Medicina Genomica
Health, Bile Acid Synthesis Disorders
Bile Acids As Determinants of Postprandial Metabolism
This study aims to understand how bile acids (BAs) appear in the bloodstream after eating and how this might affect inflammation and metabolism.
- Conditions
- Health, Bile Acid Synthesis Disorders, Postprandial Metabolism, Postprandial Lipids Metabolism
- Trial name
- PRIME (NCT06758453)
- Testing
- Dietary Challenge
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postprandial Lipid Metabolism
Effects of Intact and Disrupted Milk Fat Globule Membrane on Postprandial Metabolic Response to High-fat Dairy in Healthy Individuals
The aim of the study is to investigate the effects of milk fat globule membrane (MFGM) content and intactness on postprandial metabolic response to a high-fat meal in humans.
- Trial name
- NCT06340412
- Testing
- Sandwich with butter-like dairy product (40g milk fat) with intact MFGM. One sandwich for breakfast and one sandwich for lunch., Sandwich with butter-like dairy product (40g milk fat) with disrupted MFGM. One sandwich for breakfast and one sandwich for lunch., Sandwich with butter-like dairy product (40g milk fat) without MFGM. One sandwich for breakfast and one sandwich for lunch.
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Post-prandial Glycaemic Response, Postprandial Lipids Metabolism
Postprandial Responses to Fish Intake
Fish consumption has been increasing in recent decades due to consumer interest in the positive health effects of regular food intake, among other factors.
- Conditions
- Post-prandial Glycaemic Response, Postprandial Lipids Metabolism, Postprandial Metabolism
- Trial name
- PREFish (NCT06757608)
- Testing
- Assessment of postprandial metabolism after intake of different meat
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Spinal Cord Injuries, Postprandial Hypotension
Low-GI Diet Vs High-GI Diet in Individuals with SCI
The purpose of this pilot research project is to examine the impact of a low-glycemic index (GI) diet on postprandial hypotension and glucose control in individuals with chronic spinal cord injury.
- Conditions
- Spinal Cord Injuries, Postprandial Hypotension, Glucose Metabolism Disorders
- Trial name
- NCT05334342
- Testing
- Low-GI Diet, High-GI Diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Ohio State University
Ketosis, Postprandial Hyperglycemia
Pre-meals of 3-hydroxybutyrate in Type 2 Diabetes
Hyperglycemia following meals in patients with type 2 diabetes mellitus (T2DM) is a common problem. Recently, our group found that oral consumption of the ketone metabolite, 3-hydroxybutyrate (3-OHB), effectively stimulates…
- Conditions
- Ketosis, Postprandial Hyperglycemia, Glucose Metabolism Disorders (Including Diabetes Mellitus)
- Trial name
- PreKetone (NCT05581043)
- Testing
- 3-hydroxybutyrate (3-OHB)
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Postprandial Glucose Responses, Glucose Metabolism
The RepEAT Study: Individual Differences in Postprandial Glucose Responses and the Relation With Diet and Phenotype
Postprandial glucose responses are related to an increased risk of developing cardiometabolic diseases. Existing research recognizes the presence of inter-individual variation in postprandial glucose responses to the same meal or…
- Trial name
- RepEAT (NCT05456815)
- Testing
- Standardized diet
- Where
- Netherlands
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Physical Activity, Postprandial Metabolism
Isolating and Exploiting the Mechanisms That Link Breakfast and Human Health - Intervention
Following the establishment of causal links between breakfast consumption, the individual components of energy balance, and health it is now important to examine and target the underlying biological mechanisms involved to…
- Conditions
- Physical Activity, Postprandial Metabolism, Weight Loss
- Trial name
- NCT04417205
- Testing
- Carbohydrate Rich Breakfast, Whey protein enriched breakfast
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Bath
Hypercholesterolemia, Postprandial Hyperglycemia
Postprandial Lipemia and Glycemia Following a High-Fat Meal
The goal of this clinical trial is to determine the acute effects on postprandial lipemia and glycemia by supplementing a high-fat meal with either white button (WB) or shiitake (SH) mushroom powder in relatively healthy adults…
- Conditions
- Hypercholesterolemia, Postprandial Hyperglycemia, Lipid Disorder
- Trial name
- NCT05619952
- Testing
- Mushroom Powder
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Abdominal Obesity, Postprandial Lipemia
Alternating Energy Intake and Blood Fat Content After a Meal
Increasing evidence suggests that meal timing affects metabolic health. For example, intermittent fasting (IF) may have positive effects on plasma glucose and lipid levels, insulin sensitivity, and blood pressure.
- Conditions
- Abdominal Obesity, Postprandial Lipemia, Lipid Metabolism, Glucose Metabolism
- Trial name
- NCT04894526
- Testing
- Alternating Energy Intake, Regular Energy Intake
- Where
- Netherlands
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Postprandial Hyperglycemia, Metabolic Disorder, Glucose
Westlake N-of-1 Trials for Macronutrient Intake 2 ( WE-MACNUTR 2)
Diet and nutrition are key to maintain human health. Westlake N-of-1 Trials for Macronutrient Intake (WE-MACNUTR) trial investigates individualized postprandial glycemic responses to different proportions of dietary fat and…
- Trial name
- NCT05161182
- Testing
- High fat, low carbohydrate diet, Low fat, high carbohydrate diet
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Westlake University
Postprandial Metabolism, Appetite
Isolating & Exploiting the Mechanisms That Link Breakfast to Human Health - Acute
Following the establishment of causal links between breakfast consumption, the individual components of energy balance, and health it is now important to examine and target the underlying biological mechanisms involved to…
- Trial name
- NCT03866720
- Testing
- Carbohydrate rich breakfast, Whey protein enriched breakfast
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Bath
Postprandial Hyperglycemia, Metabolic Disorder, Glucose
Westlake N-of-1 Trials for Macronutrient Intake
This is a dietary intervention study in students and staff of Westlake University, which is designed to provide evidence in support of N-of-1 methods as an approach to advance personalized nutrition.
- Trial name
- WE-MACNUTR (NCT04125602)
- Testing
- High fat low carbohydrate diet, Low fat high carbohydrate diet
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Westlake University