Clinical trials: Postprandial Period
Postprandial Period
Effect of Drinks Containing Fruit Polyphenol Extracts and Fibre on Postprandial Glycaemia. (Glu-MIX)
Postprandial glycaemia refers to the transient rise in blood glucose levels that occurs after consuming a meal. Large fluctuations in blood glucose levels, experienced on a frequent basis, may impair the functioning of pancreatic…
- Trial name
- NCT03572296
- Testing
- Polyphenol and fibre, Fibre
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Lucozade Ribena Suntory
Blood Sugar (Glucose) Control, Postprandial Glucose
Effect of SugarLock® Peanut Skin Extract on Postprandial Blood Glucose Control
The objective of this study is to investigate the effects of pre-meal supplementation with SugarLock® peanut skin extract and white kidney bean extract on reducing or delaying postprandial blood glucose elevation and glycemic…
- Trial name
- NCT07705191
- Testing
- Peanut skin extract, White kidney bean extract, Water
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Type 2 Diabetes
A Study to Evaluate P-Glucose, Safety and Tolerability After Oral Single Dosing of AZD6370 in Type 2 Diabetic Patients
The purpose of this study is to assess the effect of AZD6370 on blood sugar and to study safety and tolerability in patients with type 2 diabetes.
- Trial name
- NCT00690287
- Testing
- AZD6370
- Where
- 3 sites in Sweden
- Volunteers
- 24 people
- Sponsor
- AstraZeneca
Hyperprolactinemia
A Study on Bioequivalence of Cabergoline Tablets in Human Body
The purpose of this study is to evaluate the bioequivalence of the test formulation and reference formulation of cabergoline tablets in healthy Chinese subjects under fasting and postprandial conditions.
- Trial name
- NCT07008417
- Testing
- Cabergoline tablets test formulation, Cabergoline tablets reference formulation
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Hyperlipoproteinemia Type I
Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other Studies
LPL (Lipoprotein Lipase) is an enzyme which plays an important role in the elimination of triglycerides (fat) and the clearance of dietary fat particles known as chylomicrons (CM) in the blood.
- Trial name
- NCT01447901
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Amsterdam Molecular Therapeutics
Glucose Response, Insulin Response
Glucose and Insulin Responses to Test Foods
In this study, postprandial glucose and insulin responses of different foods will be measured in individuals with varying body weight.
- Trial name
- NCT01671878
- Testing
- Reference Glucose, Test Food 1 (Cereal), Test Food 2 (Biscuit)
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Glycemic Response
Study of a Carbohydrate Drink in Adults
The objective of this study is to determine the postprandial glycemic response and rates of gastric emptying in healthy subjects and those with pre-diabetes and type 2 diabetes following oral ingestion of carbohydrate.
- Trial name
- NCT04313920
- Testing
- Nutritional Supplement
- Where
- 3 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Type 2 Diabetes Mellitus
Postprandial Glucodynamic Response to Insulin Glargine/Lixisenatide Fixed Ratio Combination in Japanese Patients With Type 2 Diabetes Mellitus
Primary Objective: To assess the postprandial glucodynamic response to 2 doses of insulin glargine/lixisenatide fixed-ratio combination compared to placebo in Japanese patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT02713477
- Testing
- Insulin glargine/ lixisenatide fixed-ratio combination HOE901/AVE0010, Insulin glargine HOE901
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Sanofi
Healthy
Pharmacokinetics Study of Zolpidem Hemitartarate Orodispersible Tablet 3.5 mg Formulation
The purpose of this study is to evaluate the pharmacokinetics of the new formulation of zolpidem hemitartarate orodispersible tablet 3.5 mg in male and female healthy volunteers.
- Trial name
- NCT02817750
- Testing
- zolpidem hemitartarate tablet 3.5 mg (fasting + post-prandial), zolpidem hemitartarate tablet 3.5 mg (post-prandial + fasting)
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Obesity
A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old
The purpose of this study is to investigate the acute and chronic effects of consumption fructose containing sugars and glucose in a real word setting when consumed in a manner and amount typical in the American diet.
- Trial name
- NCT01797042
- Testing
- Dietary Compliance
- Where
- United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute
Drug-induced Weight Gain
Effect of RDX-002 on Postprandial Triglycerides in Subjects Treated With Olanzapine
This Phase 1b Study RDX-002-22-09 has been planned to evaluate the effect of RDX-002 on postprandial triglycerides and ApoB48 levels in normal healthy subjects treated with the atypical antipsychotic drug, olanzapine.
- Trial name
- NCT05857566
- Testing
- RDX-002
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Response Pharmaceuticals
Diabetes Mellitus
Effect of Serving Size and Addition of Sugar on the Glycemic Response Elicited by Oatmeal
The purpose of this study was to determine the impact of serving size and the addition of sugar on the glycemic response elicited by oatmeal compared to that elicited by cream of rice cereal.
- Trial name
- Panther (NCT02506972)
- Testing
- Classic Quaker Quick Oats, Cream of Rice Cereal
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Glycemic Index Laboratories, Inc
Diabetes Mellitus, Type 2
Liquid Meal Study With Insulin Lispro With/Without Recombinant Human Hyaluronidase PH20 (rHuPH20) and Regular Human Insulin With rHuPH20 to Compare Pharmacokinetics, Postprandial Glycemic Response, and Optimal Insulin Dose in Participants With Type 2 Diabetes Mellitus (T2DM)
This is a single-center, Phase 2, randomized, double-blind, 3-way crossover meal study in participants with Type 2 Diabetes Mellitus (T2DM) to determine the optimum dose and compare the pharmacokinetics (PK) and postprandial…
- Trial name
- NCT00916357
- Testing
- Humalog, Humulin-R, Recombinant human hyaluronidase PH20 (rHuPH20)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Halozyme Therapeutics
Diabetes Mellitus, Type 2
Beta Cell Relieving and Cardiovascular Protective Effects of LANTUS Treatment in Type 2 Diabetes Patients
The purpose of this phase IV clinical trial is to investigate the effect of Insulin glargine + metformin treatment vs. sulfonylurea + metformin treatment vs. DPP-4 + metformin treatment vs.
- Trial name
- NCT01206712
- Where
- Germany
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- ikfe-CRO GmbH
Glycemic Response
Assessment of the Glycemic Responses to Nutritional Products
This study assesses the glycemic responses to nutritional products. During a study visit fasted subjects will consume one serving of the reference product or the test product.
- Trial name
- GLIN#1 (NCT05179031)
- Testing
- First Reference product (dextrose, containing 25 g of carbohydrates), Second Reference product (dextrose, containing 25 g of carbohydrates), Third Reference product (dextrose, containing 25 g of carbohydrates)
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Bioavailability of Amino Acids
Amino Acids in the Blood After Eating Yoghurt and Milk Proteins
Participants will visit the study site twice in a fasting state. Participants asked to consume one of the two study products in a random order. Participants will consume one serving of the study product (T = 0 minutes).
- Trial name
- NutraFerm2 (NCT07243730)
- Testing
- Full fat yogurt (fermented), Generic full fat pasteurized milk (non-fermented)
- Where
- Netherlands
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Prediabetes, Normal Plasma Glucose
The Effects of Nextida-GC and Whey Protein on Postprandial Glycemic and Insulinemic Responses When Given 30min Before, 10min Before or With a Standardized Breakfast Test-meal in Healthy Adults With and Without Prediabetes
The goals of this clinical trial are to learn if Nextida-GC (a peptide derived from collagen) will reduce postprandial glucose responses when taken 30 minutes before, 10 minutes before or with the first bite of a breakfast…
- Conditions
- Prediabetes, Normal Plasma Glucose, Normoglycemia
- Trial name
- NCT07174323
- Testing
- Peptide derived from collagen protein, Whey protein isolate
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- INQUIS Clinical Research
Dietary Supplement
Evaluate Effects of Sprinkled Format REDUCOSE in a Carbohydrate-rich, Mixed Meal on Post-prandial Glycemia
This is a mechanistic, single-center, double-blind, placebo- and active-controlled, three-time-period, crossover study to evaluate the effect of sprinkled format REDUCOSE compared to placebo (double-blind; confirmative) and…
- Trial name
- Stardust (NCT04877366)
- Testing
- Dietary Supplement: Sprinkled Format REDUCOSE., Reference control, Active comparator
- Where
- 2 sites in United States, Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Gestational Diabetes Mellitus in Pregnancy
Meal Tolerance Trial in Pregnant Women Diagnosed With Gestational Diabetes Mellitus.
This study is initiated to investigate the effect of a nutritional product on the 3-hr postprandial glucose response compared to a control standard breakfast at baseline and after 4 weeks of intervention.
- Trial name
- GDM-MTT (NCT02225951)
- Testing
- Nutritional product, Standard breakfast according to ADA recommendations
- Where
- Singapore
- Volunteers
- 3 people
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Prediabetic State
Investigation of Milk Peptides (Pep2Dia®) on Postprandial Blood Glucose Profile in Prediabetic Subjects
The goal is to investigate the 180 min postprandial response on blood glucose and insulin levels after intake of Pep2Dia® in two different dosages compared to placebo in the context of a meal challenge test, providing 75 g of…
- Trial name
- NCT04375449
- Testing
- Pep2dia, maltodextrin
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ingredia S.A.