Clinical trials: Postprandial Period
Diabetes Mellitus, Type 2
Sucralose in Subjects With Diabetes Mellitus Insulin Requesting
To evaluate the acute effect of a preload of sucralose in presence of carbohydrate (HC) available on the glycemic response, postprandial C peptide and satiety in patients with type 2 diabetes mellitus (DM2) in intensive insulin…
- Trial name
- SDMIR (NCT02813759)
- Testing
- Sucralose
- Volunteers
- 10 people
- Sponsor
- Universidad de Valparaiso
Obesity, Pre Diabetes
Personalized Nutrition Based on the Glycemic Response: Effect of Diet and Intestinal Microbiota
This study will investigate whether changes in the intestinal microbiota generated through a nutritional strategy based on functional foods, modifies postprandial glycemic responses in subjects with prediabetes and obesity, which…
- Trial name
- NCT05230342
- Testing
- A package containing a mix of functional foods
- Where
- 2 sites in Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Type 2 Diabetes, Glycemic Control
Blood Glucose Homeostasis in Type 2 Diabetes: the Effects of Saccharose
Hyperglycemia forms a direct and independent risk factor for the development of cardiovascular co-morbidities in type 2 diabetes.
- Trial name
- NCT00821665
- Testing
- Sucrose consumption, water consumption
- Where
- Netherlands
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus
A Study to Evaluate the Effect of Nasal Insulin on Postprandial Glycemic Control in Type 2 Diabetic Patients
Insulin is a hormone which is produced by the human pancreas for the lowering of blood sugar. In patients who don't produce enough insulin, additional insulin must be given several times per day by injections.
- Trial name
- NCT00624767
- Testing
- Insulin (recombinant human insulin), NovoLog
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Nastech Pharmaceutical Company, Inc.
Cardiovascular Risk Factors, Blood Pressure
Effect of a Specific Phenolic Compound on Blood Pressure
The study's main objective is to investigate the effects of acute consumption of a preparation containing 100 mg of a specific phenolic compound (patent pending, P201531587) on systolic BP after ingestion of a high fat meal.
- Trial name
- PHENOLPRESS (NCT02628353)
- Testing
- phenolic compound
- Where
- Spain
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Metabolic Syndrome, Obesity
Elucidating the Role of Human Small Intestine Microbiota in Explaining Differences in Postprandial Glucose Responses
It has been shown that person-specific factors, such as the fecal microbiome, influenced postprandial glycemia. The small intestine is the site of nutrient digestion and absorption.
- Conditions
- Metabolic Syndrome, Obesity, Overweight, Microbiota
- Trial name
- GLYSIMI (NCT05120661)
- Testing
- food product
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Diabetes Mellitus, Type 1, Type 1 Diabetes
Co-administration of Pramlintide and Insulin Via an Automated Dual-hormone Artificial Pancreas System in Adults With Type 1 Diabetes
One of the main challenges in maintaining tight glucose control in a closed-loop system occurs at meal times. Amylin is a gluco-regulatory beta-cell hormone that is co-secreted with insulin in response to nutrient stimuli, and is…
- Conditions
- Diabetes Mellitus, Type 1, Type 1 Diabetes, Postprandial Hyperglycemia
- Trial name
- NCT04243629
- Testing
- Rapid-Acting Insulin, Pramlintide Acetate, Artificial Pancreas
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- McGill University
Diabetes, Diabetes Type 2
ACUTE EFFECT OF CONSUMPTION OF GROUND OR WHOLE FLAXSEEDS ON BLOOD GLUCOSE IN PEOPLE WITH TYPE 2 DIABETES
This study aimed to evaluate the effect of consuming a portion of French bread combined with whole or ground flaxseed on the glycemia of people with DM 2 in a randomized, crossover clinical trial conducted with 16 people with DM…
- Conditions
- Diabetes, Diabetes Type 2, Insulin Resistance
- Trial name
- DM2 (NCT06912542)
- Testing
- Whole flaxseed bread, Ground flaxseed bread, French bread
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- Universidade Francisca
Dyspepsia, Functional Gastrointestinal Disorders
Traditional Dietary Advice Versus Low FODMAP Diet in Postprandial Functional Dyspepsia
Functional dyspepsia is common, affecting 7.2% of the global population, and associated with substantial health impairment. Almost 80% of patients with functional dyspepsia report meal-related symptoms and are classified as…
- Trial name
- NCT05810168
- Testing
- Dietary modifications
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Endothelial Dysfunction
Different Oils For Frying and Endothelial Function
The purpose of this study is to compare the effects of the consumption of different oils (olive oil, sunflower oil, sunflower plus dimethyl-polysiloxane, sunflower plus phenols) previously submitted to heating in postprandial…
- Trial name
- NCT00837317
- Testing
- Olive Oil, SF, SF+DMP, SF+phenols
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Type 1 Diabetes Mellitus
Does Protein and Fat Content of Meal Increase Glucose Concentrations
The study investigated the effects of fat protein counting (CFP) in addition to carbohydrate (CARB) counting for calculating prandial insulin dosage on blood glucose profile in patients with type 1 diabetes (T1D) on basal-bolus…
- Trial name
- NCT03333525
- Testing
- Calculation of insulin dosages for different meals
- Volunteers
- 30 people
- Sponsor
- TC Erciyes University
Ketosis, Muscle Protein Synthesis
Exogenous Ketosis and Muscle Protein Synthesis During Exercise Recovery
An acute bout of resistance exercise stimulates muscle protein synthesis (MPS) rates for up to 24-48 hours, supporting muscle growth and repair.
- Conditions
- Ketosis, Muscle Protein Synthesis, Dietary Proteins, Resistance Exercise
- Trial name
- NCT06769100
- Testing
- Ketone Monoester (KET), Ketone Monoester + Whey Protein (KET+PRO), Whey Protein (PRO)
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- McGill University
Spinal Cord Injuries
Postprandial Lipid Tracer and Exercise in Spinal Cord Injury
This study investigates the effect of upper extremity exercise on postprandial lipemia (PPL) in persons with spinal cord injury (SCI).
- Trial name
- PPLT (NCT03691532)
- Testing
- Seated control (CON), Arm cycle exercise (ACE), Liquid meal
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Miami
Oxidative Stress
Cultural Meal and Postprandial Oxidative Stress
This one-year randomized crossover study is proposed to compare the changes of postprandial oxidative stress (POS) after consumption of meals from different cultures in healthy Chinese adults, using a 'real-life, cultural meal'…
- Trial name
- NCT02006771
- Testing
- Southern Chinese meal, Northern Chinese meal, American meal
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Healthy
Postprandial Effects of Mixed Herbs and Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects
This study aims to investigate the effect of mixed of herbs and spices on gene expression of pathways associated with glucose homeostasis, oxidative stress, inflammation and its interrelation with circulating miRNA, in the…
- Trial name
- NCT02931643
- Testing
- High fat challenge breakfast, High fat challenge breakfast with mixed-spices
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lund University
Postprandial Amino Acid Concentrations in Healthy Adults
Amino Acid Concentrations in Serum After Intake of Different Protein Sources
This study assesses the amino acid concentrations in subject serum after intake of different types of proteins. The study is divided in two consecutive sub-studies.
- Trial name
- NCT06153225
- Testing
- Protein products
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Triglycerides, Weight Gain Trajectory
Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists
The goal of this clinical trial is to learn if drug RDX-002 works to treat high levels of fat (known as triglycerides, or TGs) in the blood in adults. It will also learn about the safety of drug RDX-002.
- Conditions
- Triglycerides, Weight Gain Trajectory, Cholesterol, Elevated
- Trial name
- NCT06640972
- Testing
- RDX-002
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Response Pharmaceuticals
Type 1 Diabetes Mellitus
Post-meal Insulin Dosing With Adjuvant Pre-meal Pramlintide in Children With Type 1 Diabetes Mellitus
The primary objective of this study is to examine the effect of pramlintide given pre-meal and insulin given just after a meal vs. standard therapy of pre-meal insulin on post-prandial glucose excursions.
- Trial name
- NCT00442767
- Testing
- Insulin, Pramlintide + Insulin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Montefiore Medical Center
Time Restricted Feeding
Prolonged Overnight Fast, Energy Metabolism and Skeletal Muscle Anabolic Sensitivity
Recent research shows that timing of nutritional intake and daily periods of fasting may have important health effects. In humans, limiting daily food intake to a narrow window (typically ~8 hours) can bring about some beneficial…
- Trial name
- NCT05420181
- Testing
- Short 10hr fast, Long 16h fast
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Postprandial Hyperglycemia, Overweight and Obesity
A Study of Biochemical Response to Alternative Proteins
The overall objective of this research is to determine the digestive faith and health impact of protein and fiber rich foods in different food matrices in type 2 diabetes risk population.
- Conditions
- Postprandial Hyperglycemia, Overweight and Obesity, Type2diabetes
- Trial name
- COBRA (NCT06253728)
- Testing
- High fiber and protein meal, Control
- Where
- Finland
- Volunteers
- 24 people
- Sponsor
- University of Eastern Finland
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