Clinical trials: Postprandial Period
Diabetes Mellitus, Gastroparesis
Drug Trial of Lixisenatide on Gastric Emptying and Blood Pressure Drops in Type 2 Diabetics and Healthy People
The purpose of this study is to determine the effects of the drug lixisenatide on blood sugar levels, stomach emptying, blood pressure and heart rate, release of gut hormones and blood flow in the gut after a glucose drink in…
- Trial name
- Lixi (NCT02308254)
- Testing
- Lixisenatide
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Adelaide Hospital
Diabetes Mellitus
Nippon Ultra-Rapid Insulin and Diabetic Complication Evaluation-Study (NICE-Study)
For the purpose of comparing efficacy of intensive therapy between 1) ultrarapid-acting type insulin (insulin aspart) and 2) conventional rapid-acting type insulin (R), a Multicenter Open Label Randomized Controlled Trial was…
- Trial name
- NCT00575172
- Where
- Japan
- Volunteers
- 346 people
- Sponsor
- Osaka Saiseikai Nakatsu Hospital
Type 1 Diabetes
Dual-wave Boluses in Children With Type 1 Diabetes Insulin Boluses in Children With Type 1 Diabetes
To analyze with the aid of CGM the blood sugar profiles of children receiving dual-wave versus standard bolus for dinner.
- Trial name
- NCT04668612
- Testing
- Dual-bolus, Standard bolus
- Where
- Estonia
- Volunteers
- 30 people
- Sponsor
- Tartu University Hospital
Cardiovascular Risk Factor
The Acute Effects of Meals Rich in Saturated or Unsaturated Fatty Acids on Postprandial Lipaemia in Healthy Men
Current dietary recommendations suggest that lowering intake of saturated fats or replacing it with unsaturated fats will decrease the risk of developing cardiovascular disease.
- Trial name
- CocoHeart (NCT05264233)
- Testing
- Coconut oil, Butter, Vegetable oil
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Reading
Glucose Intolerance
Effects of Diet and Exercise on Circadian Glycemia
Specific aims of the study are: 1. to evaluate whether a 24-h exposure to a 25%-carbohydrate diet will reduce postprandial glycemia to the same extent in the evening (19 h) as in the morning (7 h),. and 2.
- Trial name
- GLYCEMIA (NCT03922685)
- Testing
- Dietary manipulation (25% carbohydrate diet) and behavioral (exercise), Dietary manipulation (25% carbohydrate diet) and behavioral (sedentary)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiovascular Disease, The Metabolic Syndrome
Acute Fatty Acid Intervention Study (AFAST)
The main objective of this study is to elucidate whether different dietary fatty acids (SFA, PUFA, butter fat and margarine fat) in a high fat load will have different effects on PBMC gene expression profiles.
- Trial name
- AFAST (NCT01000194)
- Testing
- High fat meal
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Healthy Subjects, Gastric Emptying
GLP-1 - Regulatory Mechanism of Postprandial Glycemia
Synthetic GLP-1 lowers postprandial (pp) glycemia by stimulating insulin, inhibiting glucagon, and delaying gastric emptying. However, the effects of the endogenous peptide are largely unknown.
- Trial name
- NCT00980083
- Testing
- Saline, Exendin(9-39)amide
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Postprandial Distress Syndrome
A Study of Lianxiaxiaopi Granules in the Treatment of Postprandial Distress Syndrome
The goal of this clinical trial is evaluating the efficacy and safety of Lianxiaxiaopi Granules in participant population. The main questions it aims to answer are: 1.
- Trial name
- NCT06696261
- Testing
- Lianxiaxiaopi Granules, a simulated agent of Lianxiaxiaopi Granules
- Where
- 18 sites in China
- Volunteers
- 342 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Overweight , Obesity
Two-Week Stair-Climbing Exercise Snacks and Metabolic Health in Adults With Overweight or Obesity: A Pilot Study
This pilot study will evaluate whether brief bouts of stair climbing performed throughout the day for two weeks can improve metabolic health, cardiovascular fitness, and other health-related outcomes in adults with overweight or…
- Trial name
- NCT07849439
- Testing
- Stair-Climbing Exercise Snacks
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Healthy Volunteers
The Effect of Wheat Germ on Gastrointestinal Discomfort, Blood Cholesterol and Postprandial Glycaemic Response
Wheat germ is a by-product of the wheat-milling industry with high nutritional value and therefore could be used as a raw source for the preparation of food products such as bread, cookies, muffins, etc.
- Trial name
- NCT02405507
- Testing
- wheat bread with wheat germ, wheat bread without wheat germ
- Where
- 2 sites in Portugal
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Pregnancy in Diabetic, Type 1 Diabetes
Maternal ExeRcIse Timing to Optimise Postprandial Glucose in Type 1 Diabetes
Poor glycaemic control in pregnancy is a major factor leading to obstetric complications and future maternal-offspring diseases.
- Trial name
- MERIT1D (NCT05843175)
- Testing
- Exercise and meal testing (acute stimuli)
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- University of Graz
Metabolic Syndrome
Lipid and Glucose Response to Plant-based and Regular Burgers
This study evaluates the blood lipid and glucose response to two burgers: 1) A plant-based meat alternative burger and 2) a regular beef burger in a cross-over trial.
- Trial name
- NCT07766928
- Testing
- Acute consumption of different burger types
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Subjects at Cardiometabolic Risk
Grape Pomace Polyphenols and Cardiometabolic Risk
The aim of this is study is to evaluate the long-term effects of grape polyphenols in the modulation of markers of metabolic syndrome.
- Trial name
- GRAPOM (NCT03076463)
- Testing
- GRAPOM
- Where
- Spain
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Obesity
Effects of Intake of a Polysaccharides Mix on Metabolism, Hormones and Satiety in Obese Children.
AIMS Phase 1. Verify whether the intake of LibramedR is able to induce a better endocrine and metabolic profile. Phase 2. Verify whether treatment with LibramedR for 60 days produces a better glycaemic profile after oral glucose…
- Trial name
- NCT02148614
- Testing
- Libramed
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Platelet Aggregation and Inflammation
Cardioprotective Properties of Natural Anti-Platelet Activating Factor Extract From Winery By-products in Healthy Women
The purpose of this study is to investigate the anti-platelet and anti-inflammatory properties of a winery by-products extract as well as to detect extract compounds and their metabolites in biological fluids.
- Trial name
- NAPE (NCT04436263)
- Testing
- Supplement
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Cardiovascular Diseases, Cognition
Acute Impact of Whey Protein-enriched Milk Fat Globule Membrane Supplementation on Postprandial Markers of Heart and Brain Health
In a single-blind, randomised, placebo-controlled crossover manner, this study aims to assess the impact of a high-fat mixed meal containing a whey protein (WP)-enriched milk fat globule membrane (MFGM) powdered ingredient on…
- Conditions
- Cardiovascular Diseases, Cognition, Overweight or Obesity, Postmenopausal Women
- Trial name
- NCT06953232
- Testing
- Whey protein-enriched milk fat globule membrane supplement, Whey protein-based supplement
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Glycemic Response
The Impact of Fruit Juice, Fruit Juice With Pomace, or Whole Fruit on Glycemic Response
The primary aim of this clinical trial is to compare the effects of a whole orange, orange juice alone, and orange juice with pomace, and a whole apple, apple juice alone, apple juice with pomace on glycemic response.
- Trial name
- NCT04369716
- Testing
- Whole oranges, Whole Apples, Orange juice + orange pomace
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Type 2 Diabetes
Measuring Cholesterol in the Fasting and Postmeal State in Patients With Type 2 Diabetes
Many patients with type 2 diabetes have difficulty attaining cholesterol goals, partly due to the recommendations for fasting measurements that may not be practical in the typical clinical setting.
- Trial name
- NCT00287404
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina
Type 2 Diabetes
Effects of PDE-5 Inhibition on Postprandial Hyperglycemia in Type 2 Diabetes
An increase of blood flow and capillary permeability decrease the impact of an endothelial barrier for glucose and insulin allowing them to reach their target cells in peripheral insulin sensitive organ in the human body.
- Trial name
- NCT01238224
- Testing
- Tadalafil
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Vastra Gotaland Region
Obesity
Postprandial Nutrient Homeostasis Before and After Weight Loss Induced by Low-calorie Diet or RYGB
The purpose of this study is to compare the metabolic responses to low-carbohydrate and standard-carbohydrate meals in African Americans and non-Hispanic White adults with obesity and the effect of weight loss induced by…
- Trial name
- FGB (NCT03091725)
- Testing
- Roux-en-Y gastric bypass surgery, Low-calorie diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
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