Clinical trials: Postprandial Responses
Fasting, Postprandial Hyperglycemia
Postprandial Metabolome and Metabolic Flexibility
Metabolic flexibility is a process in which the body can switch energy substrates in different physiological states. This flexibility plays an important role in an individual's health because losing it increases the risk of…
- Conditions
- Fasting, Postprandial Hyperglycemia, Lipid Metabolism Disorders, Glucose Metabolism Disorders
- Trial name
- NCT06878781
- Testing
- High carbohydrate challenge, High lipid challenge, High proteinchallenge
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Medicina Genomica
Obesity, Postprandial Lipemia
Acute Effects of Dietary Proteins on Postprandial Lipemia, Incretin Responses and Subclinical Inflammation in Obese Subjects
The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.
- Conditions
- Obesity, Postprandial Lipemia, Atherosclerosis, Inflammation
- Trial name
- NCT00863564
- Testing
- Caseine, Cod, Gluten
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Type II Diabetes Mellitus, Glucose Metabolism Disorders
Whey Protein Effect on Glycaemic and Appetite Responses in T2D
The current study will investigate the effect if whey protein on postprandial glycaemia and appetite in type II diabetics, assessing incretin (GLP-1, GIP), insulin, and appetite control (leptin, PYY3-36) hormone responses.
- Conditions
- Type II Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases
- Trial name
- NCT02903199
- Testing
- Whey Protein, Hydrolysed Protein
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Northumbria University
Postprandial Metabolism, Healthy Volunteers
Postprandial Metabolic Responses to Sustainable and Non-Sustainable Meals in Healthy Young Men
This randomized crossover study evaluated the acute postprandial metabolic and hydration responses to two standardized lunch meals differing in nutritional quality and environmental footprint in healthy young men.
- Trial name
- THERMOS-LUNCH (NCT07808736)
- Testing
- Healthy-Sustainable Test Meal, Non-Sustainable Test Meal
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Parma
Type 2 Diabetes Mellitus
Glycemic and Satiety Response Study of Fibre-Enriched Pudding Products
The purpose of this study is to determine the specific properties of a variety of dietary fibres that lead to different postprandial glycemic and satiety responses in individuals at risk for type 2 diabetes.
- Trial name
- Pudding (NCT02289612)
- Testing
- Yellow Mustard Gum Fibre, Soluble Flaxseed Gum Fibre, Fenugreek Gum Fibre
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Guelph
Healthy, Healthy Volunteer
Avocado and Postprandial Responses
The purpose of this study is to see how adding avocado to a breakfast meal affects blood sugar control and signals of hunger and fullness after eating.
- Conditions
- Healthy, Healthy Volunteer, Healthy Volunteers, Healthy Adult
- Trial name
- NCT06818032
- Testing
- Negative control, Avocado, Fat and fiber addition
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Type 1 Diabetes Mellitus, Glycemic Variability
Impact of Dietary Fat and Menstrual Cycle Phases in Type 1 Diabetes
This clinical trial aims to evaluate how variations in dietary fat content and hormonal status influence postprandial glycemic response in individuals with type 1 diabetes (T1D), with a special focus on women.
- Conditions
- Type 1 Diabetes Mellitus, Glycemic Variability, Sex Characteristics, Menstrual Cycle
- Trial name
- DIABETEXX/3 (NCT07278063)
- Testing
- Low Fat Mixed Meal, High Fat Mixed Meal
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Postprandial Hyperglycemia
Determination of the PPG and Insulin Responses of Rice Alone and Rice Consumed With Sugardown™
This study was a partly controlled laboratory-based study comparing the short-term postprandial blood glucose and insulin responses produced by 3 test meals containing white rice alone or with SUGARDOWN™ (Galactomannan) in…
- Trial name
- NCT03375398
- Testing
- Rice, Sugardown™
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Therapeutics
Glycemic Control
Postprandial Glycemic Response in Adults With Type 2 Diabetes
This is a randomized, controlled, crossover study to compare the effects of two treatments on postprandial glucose in adults with type 2 diabetes.
- Trial name
- NCT05154045
- Testing
- Experimental Formula, Test Meal
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- Abbott Nutrition
Type 1 Diabetes
Polyphenol Enriched Extra-virgin Olive Oil and Postprandial Glycemia in Type 1 Diabetes (DOP)
The aims of this study are to investigate the short term effects of MUFA alone vs. MUFA plus Polyphenols contained in the extra-virgin olive oil (EVOO) on the postprandial glycemic response in patients with type 1 diabetes and to…
- Trial name
- DOP (NCT04764786)
- Testing
- EVOO+POLY, OO-POLY
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Federico II University
Healthy Volunteers
Providing Personally Tailored Dietary Suggestions Using Individual Microbiome and Glycemic Index Response.
Provide personally tailored dietary suggestions to participants based on the Personalized Prediction Engine (patent pending) owned by DayTwo.
- Trial name
- NCT02945514
- Testing
- DayTwo machine learning algorithm
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dietary Modification, Diabetes Mellitus Type 2
Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus
To compare the acute effect of soluble fiber intake from foods or supplement after a common meal on postprandial plasma glucose and insulin in patients with type 2 diabetes.
- Conditions
- Dietary Modification, Diabetes Mellitus Type 2, Insulin Tolerance, Diabetic Blood Glucose Monitoring
- Trial name
- NCT02204384
- Testing
- HFD Meal: High fiber from food, HFS Meal: High fiber from supplement, UF Meal: usual amount of fiber
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Metabolic Health, Gut Hormones
Breaking Sitting and Metabolic Health in Sedentary Overweight and Obese Adults
The purpose of this project is to investigate the effects of breaking up prolonged sitting on postprandial metabolic responses, gut hormones secretion and energy balance in sedentary overweight and obese adults.
- Conditions
- Metabolic Health, Gut Hormones, Energy Balance
- Trial name
- NCT05306678
- Testing
- Prolonged sitting, Breaking sitting
- Where
- Taiwan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Gastric Emptying, Diabetes Mellitus
The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses.
The purpose of this study is to determine whether 3 g cinnamon was sufficient to delay the gastric emptying rate of a high-fat solid meal and subsequently reduce postprandial blood glucose and lipid responses, oxidative stress…
- Trial name
- CinnGastEmpt (NCT01350284)
- Testing
- Cinnamon
- Where
- Ireland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Healthy
Postprandial Glycemia in Orange Products
The primary objective of the study is to compare the effects of a whole orange, orange juice alone, and orange juice with pomace on 2 hr glycemic response as measured by maximal glucose concentration.
- Trial name
- POR (NCT03685201)
- Testing
- Orange Juice1, Orange Juice2, Raw Orange
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Healthy Nutrition
Sex Differences in Metabolism Following a High-fat Meal
Long-term consumption (i.e., several weeks to months) of a diet that is high in fat (>35% daily calories from fat) is associated with the development of insulin resistance, a condition that can lead to a diagnosis of type 2…
- Trial name
- HFM (NCT05332301)
- Testing
- High-fat test meal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kirsten Bell
Glycemic Response
The Impact of Fruit Juice, Fruit Juice With Pomace, or Whole Fruit on Glycemic Response
The primary aim of this clinical trial is to compare the effects of a whole orange, orange juice alone, and orange juice with pomace, and a whole apple, apple juice alone, apple juice with pomace on glycemic response.
- Trial name
- NCT04369716
- Testing
- Whole oranges, Whole Apples, Orange juice + orange pomace
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Cardiovascular Diseases
Effectiveness of Sacha Inchi Supplementation on Postprandial Inflammation
The postprandial state increases triglyceride-rich lipoproteins and lipopolysaccharide (LPS) levels, promoting cellular lipids accumulation, insulin resistance, increased inflammatory markers and the formation of foam cells, a…
- Trial name
- ESISOPI (NCT02886169)
- Testing
- High fat meal with Sacha Inchi, high saturated fat meal
- Where
- Colombia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Icesi
Blood Sugar Response
Postprandial Glycemic Response to Polyphenol-fortified Snack Bars
Consuming plant chemicals (e.g., polyphenols) may have beneficial effects on human health that, if confirmed, may warrant inclusion in combat rations.
- Trial name
- NCT02763020
- Testing
- Fruit extracts high in polyphenols
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Hyperkalemia, Chronic Kidney Disease Requiring Chronic Dialysis
Effect of Viscous Fiber on Postprandial Kalemic Response in Hemodialysis Patients
High blood potassium levels (hyperkalemia) is a major problem for people with kidney failure undergoing hemodialysis treatment. In order to reduce the risk of hyperkalemia, people with kidney failure are advised to limit or avoid…
- Trial name
- NCT05086185
- Testing
- Kalemic Response to Orange Juice, Kalemic Response to Orange Juice with Fiber
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nevada, Reno