Clinical trials: Postsurgical Pain
Postoperative Pain
Femoral Nerve Block, Periarticular Nerve Group (PENG) Block, and Preoperative IV Fentanyl
The pericapsular nerve group block is a regional anesthetic technique described in 2018, developed primarily in total hip arthroplasties for postoperative analgesia with motor sparing benefits.
- Trial name
- NCT06537323
- Testing
- Femoral nerve block with0.25% bupivacaine guided by ultrasound., PENG block with0.25% bupivacaine guided by ultrasound., Preoperative IV fentanyl 100microgram
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Ceserean Section and Postoperative Pain
Analgesic Effect of Erector Spinae Plane Block After Caesarean Section
Background: Our hypothesis was that bilateral ESP block applied from the transverse process of T9 in women who underwent elective cesarean section with pfannenstiel incision under spinal anesthesia could provide effective…
- Trial name
- AnESPaCS (NCT04599842)
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Total Knee Arthroplasty
Ultrasound-guided Continuous Proximal Adductor Canal vs Continuous Femoral Nerve Block for Postoperative Pain Control and Rehabilitation Following Total Knee Arthroplasty
The purpose of the study is to compare continuous femoral nerve block with continuous proximal adductor canal block for postoperative pain control and rehabilitation.
- Trial name
- NCT02495805
- Testing
- Continuous proximal adductor canal block, Continuous femoral nerve block
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Nerve Block, Anesthesia, Local
Sensory Distribution of Lateral Femoral Cutaneous Nerve Block
The purpose of this study is to investigate and describe the anatomical distribution of the sensory outcome following LFCN block (LFCN = lateral femoral cutaneous nerve) in relation to the incisional lines after Total Hip…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT02957903
- Testing
- Ropivacaine, Isotonic Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Postoperative Pain
"The Efficiency of Laparoscopic-assisted Transversus Abdominis Plane Block for Post-laparoscopic Cholecystectomy Pain
Laparoscopic cholecystectomy (LC) is a minimally invasive surgical procedure that causes moderate pain in the early postoperative period.
- Trial name
- NCT04641403
- Testing
- The surgeon performed Laparoscopic-assisted TAP (LTAP) block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Private Medicabil Hospital
Pain, Postoperative, Quality of Life
Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment
In this randomized controlled double-blinded study, subjects will be assigned to one of two study groups to either be anesthetized with Bupivacaine or Lidocaine prior to needed treatment of pulpectomy/endodontic debridement on a…
- Trial name
- B-OHIP14 (NCT04787731)
- Testing
- Bupivacaine Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Pain, Postoperative
Comparison of Efficacy of Naproxen Versus Ibuprofen
Comparison between Naproxen and Ibuprofen in management of post operative endodontic pain was done.Total 116 patients were selected and divided in to two groups.One group was given Naproxen and other was given Ibuprofen.
- Trial name
- NCT04947566
- Testing
- Comparison of Efficacy of Naproxen versus Ibuprofen
- Where
- 2 sites in Pakistan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Analgesia
Regional Blocks for Lumbar Disc Surgery Analgesia
Objective The goal of this prospective randomized controlled experiment was comparing the analgesic efficacy, opioid needs, and adverse effect profiles of Paravertebral Block (PVB), Thoracolumbar Interfascial Plane Block (TLIP)…
- Trial name
- NCT06933641
- Testing
- Regional Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Pain, Postoperative, Respiratory Complication
Thoracic Epidural Analgesia and Bilateral Erector Spinae Plane Block on Postoperative Pain in Open Heart Surgeries
Postoperative pain negatively effects respiratory functions in open heart surgeries. The aim of the study is to compare the effects of thoracic epidural analgesia (TEA) and erector spinae plane block (ESPB) on postoperative pain…
- Trial name
- NCT06098859
- Testing
- Thoracic epidural analgesia, Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pain, Postoperative
Comparison Of Erector Spinae Plane Block With Transversus Abdominis Plane Block For Postoperative Pain Management In Patients Undergoing Total Abdominal Hysterectomy
Hysterectomy is the second most common major Obstetric/gynecology procedure worldwide and one of the most common procedures in our institute. Post-operative pain is one of the most common complications following hysterectomy.
- Trial name
- NCT05521841
- Testing
- Erector Spinae Plane Block(Bilateral Ultrasound Guided Erector Spinae Plane Block), Transversus abdominis plane block(Bilateral Ultrasound-guided bilateral Transversus abdominis plane block)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Pain
Ear Acupuncture for Pain Associated With Ambulatory Arthroscopic Knee Surgery
The investigators propose to complete a randomized controlled trial to compare ear acupuncture at Cingulate gyrus, thalamus, omega 2, shen-men, and point zero on the right and left ear plus standard of care versus standard of…
- Trial name
- BFAKnee (NCT01447329)
- Testing
- Ear Acupuncture, Standard Treatment
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Deep Caries
Silver Diamine Fluoride After Minimal Caries Removal Technique in Asymptomatic Young Permanent Teeth With Deep Caries
This study is comparing between the Silver Diamine Fluoride after minimal caries removal versus glass ionomer in permanent teeth with open apex
- Trial name
- NCT03568474
- Testing
- Silver Diamine Fluoride, Glass Ionomer
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Neural Therapy of Huneke
Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal Ligation
The aim of this study was to explore the effect of neural therapy on postoperative pain and discomfort such as abdominal swelling; and gynecologic symptoms such as dysmenorrhea, dyspareunia, amount of menstrual bleeding and…
- Conditions
- Pain, Postoperative, Neural Therapy of Huneke, Dysmenorrhea, Dyspareunia
- Trial name
- NCT03761862
- Testing
- Neural Therapy
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain, Postoperative
Comparison of Post-operative Pain Frequency
The objective of this study is: To compare the post-operative pain frequency after single visit root canal versus multiple visit root canal treatment in patients with non-vital teeth Post-operative pain is less frequent after…
- Trial name
- NCT04944589
- Testing
- ROOT CANAL TREATMENT
- Where
- Pakistan
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Periapical Periodontitis
Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8
Comparing the effect of Simvastatin versus calcium hydroxide used as an intracanal medicament on Post-operative Pain and Total amount of IL-6 and IL-8 in Periapical Fluids of lower premolars in patients with Symptomatic Apical…
- Trial name
- NCT05525013
- Testing
- Simvastatin Powder, Calcium Hydroxide
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Choroidal Melanoma, Melanoma
Pain Relief - Tramadol Versus Ibuprofen
The purpose of this study is to assess post operative pain following the insertion of radioactive plaque for choroidal melanoma in patients after receiving either ibuprofen or tramadol.
- Conditions
- Choroidal Melanoma, Melanoma, Eye Neoplasms
- Trial name
- NCT00111046
- Testing
- Ibuprofen, Tramadol
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Liverpool University Hospital
Postoperative Pain Management After Total Hip Arthroplasty
Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion
This study will focus on patients undergoing total hip arthroplasty and Loma Linda University Medical Center \& East Campus. These patients will be randomized to receive a low dose lidocaine infusion or placebo, in addition to…
- Trial name
- NCT01108562
- Testing
- Lidocaine, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Pain, Postoperative
Fentanyl Ultra Low Doses Effects on the Nociceptive Threshold
Exaggerated pain and hyperalgesia are major issues after surgery and can lead to chronic pain. Opioid are parts of pain sensitization processes but remain absolutely necessary in the intraoperative period.
- Trial name
- FENTANULD (NCT00454259)
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Post Operative Pain
Comparison Between Two Instrumentation Techniques on Postoperative Pain and Level of Neuropeptides
General aim: assessment of post operative pain and time of preparation with the execution of manual-less technique and conventional technique.
- Trial name
- NCT07357233
- Testing
- Manual-less, Conventional technique
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Apical Periodontitis, Dental Pulp Necrosis
Postoperative Pain and PTN and Reciproc
In this clinical trial, the researchers will investigate the effect of single-file reciprocating file system (Reciproc) versus multi-file rotational file systems (ProTaper Next) on the postoperative pain in adult patients who…
- Trial name
- NCT03380585
- Testing
- Reciprocating single-file system, Rotational multi-file system.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isparta Military Hospital
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