Clinical trials: Postsurgical Pain
Erector Spinae Plane Block, Wound Infiltration
Postoperative Pain in Lumbar Disc Surgery
This study included 46 patients who underwent lumbar disc herniation surgery under general anesthesia. After the operation, US-guided ESPB was performed on Group E, and WI was performed on Group W.
- Conditions
- Erector Spinae Plane Block, Wound Infiltration, Lumbar Disc Herniation, Postoperative Pain
- Trial name
- Pain (NCT06844747)
- Testing
- erector spinae plane block(ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Endodontically Treated Teeth, Post Operative Pain
Effect of Intra-Canal Cryotherapy on Postoperative Pain After Endodontic Procedures
The goal of this randomised clinical trial is to evaluate the effect of cryotherapy on postoperative pain after primary and secondary root canal treatment.
- Trial name
- NCT06134713
- Testing
- cryotherapy with sterile saline at 2.5ºC, control with sterile saline at room temperature
- Where
- United Arab Emirates
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ajman University
Postoperative Pain
Anesthesia and Postoperative Pain
The purpose of this study is to compare post-operative pain after anesthesia with either isoflurane or propofol. Each group will be further randomized to receive intranasal nicotine or placebo in order to detect potential…
- Trial name
- NCT00232817
- Testing
- Nicotine (drug)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Osteoarthritis, Knee
Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
This study will evaluate the use of a local injection around the knee (periarticular) during total knee replacement (TKR) surgery to see if it reduces postoperative pain levels.
- Trial name
- NCT02570503
- Testing
- Ropivacaine, Ketorolac, Clonidine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Postoperative Pain, Edema
Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery
A randomized clinical trial will be performed in parallel, placebo controlled, triple-blind to evaluate the effectiveness of the association Bromelina and Horse-chestnut (titrated in escin) (Noflogo®, Mavenpharma s.r.l., Rome…
- Conditions
- Postoperative Pain, Edema, Swelling Lips & Face
- Trial name
- NCT04657874
- Testing
- Bromelains and Escin Oral Tablet
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Postoperative Pain
Oral Gabapentin Versus Placebo for Treatment of Postoperative Pain Following Photorefractive Keratectomy
The purpose of this study is to determine the effectiveness of an oral medication called gabapentin in reducing pain after Photorefractive Keratectomy (PRK) eye surgery and to assess the frequency of use of rescue medication…
- Trial name
- NCT00793910
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Post Operative Pain
Comparison Between Bupivacaine and Bupivacaine With Dexmedetomidine in Caudal Block for Post Operative Pain Control
The aim of this study is to compare the duration of analgesia, sedation, and intra and postoperative hemodynamics. This drug is recently available in Pakistan.
- Trial name
- NCT05919173
- Testing
- Bupivacaine Hydrochloride 0.25% Injection Solution, Bupivacaine Hydrochloride 0.25% Injection plus Dexmedetomidine 1 microgram/kg body weight
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Postoperative Pain, Respiratory Complication
TENS for the Treatment of Pain and Respiratory Function Following Mastopexy With Augmentation
Background: Pain after breast plastic surgery affects quality of life. Physical therapy offers effective interventions for this condition, such as transcutaneous electrical nerve stimulation (TENS).
- Trial name
- NCT06202794
- Testing
- Experimental: Experimental group
- Where
- Chile
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Finis Terrae University
Shoulder Pain, Injury of Shoulder Region
Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
The purpose of this study is to determine the Finger Blood Glucose (sugar) when dexamethasone is added to a local anesthetic for a shoulder nerve block procedure.
- Conditions
- Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder, Disorder of Rotator Cuff
- Trial name
- NCT01538459
- Testing
- Dexamethasone, Bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lifespan
Anesthesia, Local, Postoperative Pain
Comparison of Lateral and Medial Approaches to Costoclavicular Brachial Plexus Block in Pediatrics
In upper extremity surgeries, the brachial plexus block can be performed with different techniques at various levels depending on the proximal and distal level of the surgery.
- Trial name
- NCT04786756
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Pain
Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
This is a randomized, double-blinded, placebo-controlled trial to compare the effectiveness of IV oxytocin infusion to placebo on peri-operative opioid consumption and reducing post-operative pain following a minimally invasive…
- Trial name
- NCT06483659
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Acute Postoperative Pain
Subtenon and Intravenous Dexmedetomidine Effect on Patients Undergoing Cataract Surgery
The study designed to compare the effects and the safety of adding dexmedetomidine to local anesthetics and its intravenous administration in subtenon block in patients undergoing cataract surgery.
- Trial name
- NCT04668456
- Testing
- Dexmedetomidine, lidocaine 2%, bupivacine 0.5%
- Where
- 3 sites in Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Postoperative Pain
Can the Different Instruments Used ın Root Canal Treatment Have an Effect on Postoperative Pain?
Root canal treatment is a treatment method in which the pulp is irreversibly infected due to caries or trauma or when the pulp loses its vitality.
- Trial name
- NCT05927025
- Testing
- Hand K-files
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Inguinal Hernia
Comparative Study on the Post-operative Pain and Other Outcomes of Mesh Fixation With Prolene vs Vicryl vs Skin Staples in Lichtenstein Inguinal Hernia Repair.
We are going to see the outcome measures for patient and compare them across two groups, those who are undergoing mesh fixation for inguinal hernia by sutures, and those who are fixated by skin staples.
- Trial name
- NCT07210424
- Testing
- Mesh Fixation
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Postoperative Pain, Trismus
Effect of CGF on Short Term Clinical Outcomes After Partially Impacted Mandibular Third Molar Surgery
The aim of this study was to evaluate the effectiveness of concentrated growth factor (CGF) on soft tissue healing and postoperative side effects following third molar surgery.
- Conditions
- Postoperative Pain, Trismus, Edema
- Trial name
- CGF (NCT03913884)
- Testing
- Concentrated growth factor, Non-Concentrated growth factor Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Morphine
Epidural Low Dose Morphine in Postoperative Pain After Posterior Lumbar Spinal Surgery
The effect of epidural low-dose morphine-soaked microfibrillar collagen sponge in postoperative pain control after posterior lumbar spinal surgery: a randomized, double-blind, placebo-controlled study
- Trial name
- NCT02067338
- Testing
- 1 mg morphine soak in epidural oxidized cellulose, normal saline
- Where
- Thailand
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pain Postoperative
Apical Patency and Postoperative Pain.
The purpose of this study is to determine whether maintaining an apical patency causes postoperative pain in posterior teeth with necrotic pulp and apical periodontitis.
- Trial name
- NCT02768285
- Testing
- APICAL PATENCY
- Where
- Turkey (Türkiye)
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Isparta Military Hospital
Asymptomatic Necrotic Teeth
Effect of Triple Antibiotic Paste as an Intracanal Medication With an Anti-Inflammatory Drug on Post-operative Pain.
The purpose of this study is to determine whether the use of triple antibiotic paste as intracanal medication with an anti-inflammatory drug, compared to a calcium hydroxide will reduce postoperative pain and intracanal bacteria…
- Trial name
- NCT02907489
- Testing
- triple antibiotic paste with an anti-inflammatory drug
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Dental Pain
A Study of Acetaminophen for Post Surgical Dental Pain
To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to…
- Trial name
- NCT04018612
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Post Operative Pain
The Effect of Platelet Rich Plasma (PRP) on Post Operative Pain in Anterior Cruciate Ligament Reconstruction
The purpose of this research study is to investigate whether or not platelet rich plasma (PRP) may help to improve tendon healing and decrease post operative pain in patients undergoing anterior cruciate ligament (ACL)…
- Trial name
- NCT01765712
- Testing
- Anterior Cruciate ligament reconstruction bone patellar tendon bone autograft, Platelet Rich Plasma
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brian Walters
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