Clinical trials: Postthrombotic Syndrome
Post Thrombotic Syndrome, Deep Vein Thrombosis
Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS)
The investigators plan to perform an exploratory study to investigate the effects of electro-stimulation of the legs on the symptoms and clinical findings of post thrombotic syndrome (PTS), as well as quality of life of patients…
- Conditions
- Post Thrombotic Syndrome, Deep Vein Thrombosis, Venous Stasis Syndrome, Venous Insufficiency
- Trial name
- VeinoPlus (NCT00858130)
- Testing
- VeinOPlus
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of North Carolina, Chapel Hill
Deep Vein Thrombosis
Feasibility Study of Exercise in Patients With Leg Blood Clots
The purpose of this pilot study is to assess the feasibility of determining the effects of a structured exercise program started two to four weeks after diagnosis of a first episode lower-extremity deep vein thrombosis (DVT) for…
- Trial name
- EXPERT (NCT00910364)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Iliac Vein Thrombosis
Substudy - Evaluation of Patients With Iliac Vein Thrombosis
Patients with previous diagnosis of iliac vein thrombosis are enrolled in this registry. Using standardized questionnaire, clinical data detailing venous thromboembolism and contributing VTE risk factors are recorded.
- Trial name
- NCT03148548
- Testing
- thrombophilia screening
- Where
- Germany
- Volunteers
- 85 people
- Sponsor
- Cardioangiologisches Centrum Bethanien
Venous Thrombosis, Postthrombotic Syndrome
Ultrasound-enhanced Thrombolysis Versus Standard Catheter Directed Thrombolysis for Ilio-femoral Deep Vein Thrombosis
Patients with deep vein thrombosis (DVT) of the ilio-femoral veins have increased risk for developing post-thrombotic syndrome (PTS) and recurrent venous thromboembolism compared to more distal DVT.
- Trial name
- BERNUTIFUL (NCT01482273)
- Testing
- CDT+US group, CDT-US group
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Deep Vein Thrombosis of Lower Limb, Postthrombotic Syndrome
Acute or Subacute Iliofemoral Vein Thrombosis: Aspiration for Flow Restoration Versus Standard Anticoagulation
This trial is a prospective, multicenter, randomized controlled, superiority study. According to the inclusion and exclusion criteria for clinical research subjects, 104 patients with acute deep vein thrombosis involving the…
- Trial name
- IF-FLOW (NCT07573618)
- Testing
- Thrombosis aspiration
- Volunteers
- 104 people
- Sponsor
- Weiwei Wu
Deep Venous Thrombosis, Post-thrombotic Syndrome
Novel PET/CT and Treatment Strategies to Reduce PTS Following DVT
The goal of this study is to develop strategies that will improve outcomes for patients with deep vein thrombosis (DVT), using in vivo FDG-PET inflammation imaging to better predict the development of the post-thrombotic syndrome…
- Trial name
- NCT03195777
- Testing
- PET/CT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Post Thrombotic Syndrome, Deep Vein Thrombosis
Physical Activity in Children at Risk of Post-thrombotic Sequelae (PACT)
'The PACT trial' is randomized pilot trial to demonstrate the feasibility and potential effectiveness of a personal "fitness tracker" to improve adherence to an activity regimen following an initial acute DVT in children.
- Trial name
- PACT (NCT03075761)
- Testing
- Fitbit, 30-minute education session
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Texas Southwestern Medical Center
Post Thrombotic Syndrome, Venous Thromboses
Exercise Tolerance After Venous Recanalization for Post-thrombotic Syndrome
Post-thrombotic syndrome (PTS) is the most frequently observed chronic complication of deep vein thrombosis (DVT), with an estimated cumulative incidence of 20-50%.
- Conditions
- Post Thrombotic Syndrome, Venous Thromboses, Claudication, Intermittent
- Trial name
- ETERecaVSPT (NCT05794932)
- Testing
- Stress test
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Montpellier
Post-thrombotic Syndrome, Deep Vein Thrombosis Leg
Mechanisms of Deep Vein Thrombosis (DVT) and Vein Wall Fibrosis
The goal of this study is to determine the safety and tolerability or efficacy of adjunctive treatments (including rosuvastatin 20 mg daily) in combination with standard anticoagulation therapy (Factor Xa inhibitors) in patients…
- Trial name
- NCT04833764
- Testing
- Rosuvastatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Khanh Nguyen
Deep Venous Thrombosis, Post Thrombotic Syndrome
Venous Thrombectomy/Thrombolysis Outcome Registry
Deep Venous Thrombosis affects more than 350,000 individuals each year in the U.S.The Registry will track patient outcome and quality of life over 60 months for treatment with anticoagulation and elastic compression stockings and…
- Trial name
- VETTOR (NCT02113475)
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- Heart and Vascular Outcomes Research Institute
Vascular, DVT - Deep Vein Thrombosis
Outcomes of Iliac Vein Stenting With Dedicated Venous Stents in Treatment of Chronic Post-thrombotic Venous Ulcers
Outcomes of iliac vein stenting with dedicated venous stents in treatment of chronic post-thrombotic venous ulcers Deep vein thrombosis (DVT) affects 1 to 3 individuals per 1000 annually.
- Conditions
- Vascular, DVT - Deep Vein Thrombosis, Post Thrombotic Syndrome, Venous Ulcer of Leg
- Trial name
- NCT07762222
- Testing
- dedicated venous stenting, Dedicated venous stent / iliofemoral dedicated venous stenting
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Deep Vein Thrombosis, Post-thrombotic Syndrome
Elastic Compression Stockings for Prevention of Post-thrombotic Syndrome
Post thrombotic syndrome (PTS) is a frequent and burdensome complication of proximal deep-vein thrombosis.Therapeutic options for PTS are limited and mainly rely on its prevention.
- Trial name
- CELEST (NCT01578122)
- Testing
- 25mmHg ECS, 35 mmHg ECS
- Where
- 57 sites in France
- Volunteers
- 350 people
- Sponsor
- Laboratoires Innothera
Post-Thrombotic Syndrome
The MUFFIN-PTS Trial
In this randomized controlled trial (RCT), the investigators will determine whether a 6-month course of oral Micronized Purified Flavonoid Fraction (MPFF 1000 mg daily), compared with placebo, improves the symptoms and signs of…
- Trial name
- MUFFIN-PTS (NCT03833024)
- Testing
- Micronized Purified Flavonoid Fraction
- Where
- 7 sites in Canada
- Volunteers
- 88 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Postthrombotic Syndrome
Flow Augmentation Study in Postthrombotic Patients
Rationale: Stent therapy has been proven to be an effective form of therapy in the treatment of chronic iliofemoral and iliocaval post-thrombotic obstruction.
- Trial name
- NCT03111758
- Testing
- Flow augmentation
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Maastricht University Medical Center
Post Thrombotic Syndrome
The Use of Intermittent Pneumatic Compression Device for Symptomatic Relief in Patients With Post Thrombotic Syndrome
The use of ActiveCare+S.F.T 3rd generation (an Intermittent Pneumatic Compression Device) will improve quality of life in patients suffering from Post Thrombotic Syndrome compared to compression stockings which is the current…
- Trial name
- NCT01637428
- Testing
- ActiveCare+S.F.T 3rd generation
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Postthrombotic Syndrome
Prevalence of Post-Thrombotic Syndrome in Deep-Vein Thrombosis (DVT) Patients Treated With Dabigatran
The primary objective in this cross-sectional study is to assess the prevalence of post-thrombotic syndrome (PTS) in the two treatment arms of the RE-COVER studies (warfarin versus dabigatran).
- Trial name
- DABI-PTS (NCT03050138)
- Where
- 3 sites in Canada, Norway and 1 more
- Volunteers
- 351 people
- Sponsor
- Oslo University Hospital
Venous Recanalisation
Clinical and Hemodynamic Evaluation After Venous Recanalization of Post-thrombotic Iliofemoral Syndromes
Post-thrombotic syndrome (PTS) is the most common chronic complication of deep vein thrombosis (DVT). The endovascular recanalization and stenting technique has become the gold standard treatment for medically resistant and…
- Trial name
- CHEVROPIS (NCT05954663)
- Testing
- Basic demographic information
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Hospices Civils de Lyon
Post Thrombotic Syndrome, Venous Thromboembolism
Long Term Assessment of Post Thrombotic Syndrome : OPTIMEV Study ( SPOT )
Post-thrombotic syndrome (PTS) is a frequent and burdensome complication of deep-vein thrombosis (DVT). In the absence of curative treatment of established PTS, its management is based on the prevention of its occurrence thanks…
- Conditions
- Post Thrombotic Syndrome, Venous Thromboembolism, Cardiovascular Diseases
- Trial name
- SPOT (NCT03054727)
- Testing
- Villalta phone score > or = to 5, Villalta phone score < 5
- Where
- France
- Volunteers
- 2,475 people
- Sponsor
- Association des Médecins Vasculaires Hospitaliers
Venous Thromboembolic Disease, Post Thrombotic Syndrome
Long-term Outcome After Edoxaban Versus Vitamin K Antagonists for Acute VTE
The HOKUSAI post VTE study contains of two different research questions; one on the long term outcomes of deep vein thrombosis and one on the long term effects of pulmonary embolism, post thrombotic syndrome (PTS) and chronic…
- Conditions
- Venous Thromboembolic Disease, Post Thrombotic Syndrome, Chronic Thromboembolic Pulmonary Hypertension, Quality of Life
- Trial name
- HOKUSAIpostVTE (NCT04007653)
- Testing
- Observation
- Where
- Netherlands
- Volunteers
- 1,200 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Deep Venous Thrombosis
Comparison Between Xarelto Versus Warfarin in the Recanalization Rate of Deep Venous Thrombosis in Patients Legs.
This is a prospective, randomized study, aiming to evaluate patients with Deep Venous Thrombosis in lower limbs and the recanalization rates evaluated with DUPLEX ultrasound, as so the clinical outcomes in patients submitted to…
- Trial name
- DVT (NCT02704598)
- Testing
- Rivaroxaban, Warfarin
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital do Servidor Publico Estadual