Clinical trials: Posttraumatic Stress Disorder, completed
Post-Traumatic Stress Disorder
A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder
This study is open to people aged 18 to 65 who have post-traumatic stress disorder. The purpose of this study is to find out whether a medicine called BI 1358894 improves symptoms in people with post-traumatic stress disorder.
- Trial name
- NCT05103657
- Testing
- BI 1358894
- Where
- 61 sites in United States, Croatia and 6 more
- Volunteers
- 318 people
- Sponsor
- Boehringer Ingelheim
Post Traumatic Stress Disorder, Inflammation
Probiotic (LGG) for Veterans With PTSD
Exaggerated inflammation in the body and brain is thought to play a role in the vulnerability to and aggravation and perpetuation of adverse consequences among those with posttraumatic stress disorder (PTSD).
- Trial name
- NCT04150380
- Testing
- Lactobacillus rhamnosus GG (LGG; ATCC strain 53103; CRMTS #11272; PTS #3766)
- Where
- United States
- Volunteers
- 383 people
- Sponsor
- VA Eastern Colorado Health Care System
Chronic Pain, Posttraumatic Stress Disorders
Pain Management Using Mobile Technology in Veterans With PTSD and TBI
Up to half of military veterans with traumatic brain injury (TBI) also suffer from co-occurring posttraumatic stress disorder (PTSD).
- Conditions
- Chronic Pain, Posttraumatic Stress Disorders, Traumatic Brain Injury
- Trial name
- NCT02237885
- Testing
- NeuroSky MindWave Mobile
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Duke University
Post-Traumatic Stress Disorders
Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder
The purpose of this study is to obtain data investigating the safety and efficacy of eszopiclone for the treatment of post-traumatic stress disorder (PTSD)-related sleep disturbance and the impact of improved sleep with…
- Trial name
- NCT00120250
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Massachusetts General Hospital
Post-traumatic Stress Disorder
Using Reconsolidation Blockade to Treat Trauma Related Disorders After Paris Attacks: an Effectiveness Study
The purpose of this study is: (1) to examine the effectiveness of reconsolidation blockade as a treatment for trauma-related disorders, (2) to evaluate the feasibility of implementing this new treatment on a large scale in a…
- Trial name
- PARIS-MEM (NCT02789982)
- Testing
- β-adrenergic blocker propranolol, Treatment as usual
- Where
- 20 sites in France, Martinique
- Volunteers
- 364 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delivery, Post Partum
Evaluation of Postpartum Posttraumatic Stress Disorder at Angers University Hospital (ESPT-PP)
The purpose of this study is to estimate the prevalence of post-traumatic stress disorder (PTSD) at one month in women who have given birth at the University Hospital of Angers over a period of 1 year.
- Trial name
- ESPT-PP (NCT04160273)
- Testing
- patient questionnaire and telephone follow-up
- Where
- France
- Volunteers
- 1,451 people
- Sponsor
- University Hospital, Angers
Post Traumatic Stress Disorder
The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
The Safety and Tolerability of COMP360 in Participants with Post-traumatic Stress Disorder
- Trial name
- NCT05312151
- Testing
- Psilocybin
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 22 people
- Sponsor
- COMPASS Pathways
Stress Disorders, Posttraumatic, Tobacco Use Disorder
Nicotine Patch Pretreatment for Smoking Cessation in PTSD
This study seeks to evaluate the relationship between PTSD, abstinence, and factors associated with relapse in the context of a randomized, clinical smoking cessation trial.
- Trial name
- NCT00625131
- Testing
- Nicotine, Cognitive Behavioral Therapy for Smoking Cessation, Bupropion Sustained Release (SR)
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
To Compare 2 Models of Midwifery Care in Maternity Care
Support and Personalized Care in Alternative Midwifery Birth Units Versus Traditional Units in France: Effects on the Psychological Health of Couples and on the Health of the Mother and Child at the Age of 2 Years.
Majority of pregnancies and childbirths in France occur without complication. While the impact of care failure on maternal and neonatal morbi-mortality is now well- established, the literature reveals that an overmedicalization…
- Trial name
- PhysioCareTwo (NCT06630741)
- Testing
- alternative midwifery units (AMU)
- Where
- 3 sites in France
- Volunteers
- 793 people
- Sponsor
- Rennes University Hospital
Dysthymic Disorder
Desvenlafaxine Monotherapy in Dysthymia
This multi-centred study will be conducted at two centres. The design will be an open label, flexible-dose study. This investigation will evaluate the efficacy of Desvenlafaxine monotherapy for patients who meet diagnostic…
- Trial name
- NCT01948895
- Testing
- Desvenlafaxine
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Post Traumatic Concerns, Post Traumatic Stress Disorder
A Comparative Effectiveness Trial of Optimal Patient-Centered Care
The nation's trauma care system, which includes trauma center hospitals \& emergency departments, is where over 30 million Americans receive care after traumatic injuries each year.
- Conditions
- Post Traumatic Concerns, Post Traumatic Stress Disorder, Depression and Suicide Ideation, Alcohol and Drug Use
- Trial name
- TSOS 5 (NCT02274688)
- Testing
- Stepped Care Management
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- University of Washington
Anxiety Disorders, Posttraumatic Stress Disorder
Exercising With Anxiety: Can Cognitive Behavioural Techniques Help People With Anxiety-related Disorders Exercise More?
Anxiety-related disorders such as panic disorder, social anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorder are among the most prevalent mental health disorders affecting Canadian adults.
- Conditions
- Anxiety Disorders, Posttraumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04026152
- Testing
- Resistance training, Unified Protocol
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- University of Regina
PTSD
Monoamine Transporters Genotypes: Risk of PTSD and Related Comorbidities
Dr. Wang's merit review is aimed at providing a better understanding of the relationship between SLC6A3/SLC6A4 and the mental health of veterans exposed to high levels of combat stress, specifically focusing on PTSD symptoms…
- Trial name
- MTG (NCT00403455)
- Testing
- Paroxetine
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-Traumatic Stress Disorder
Examining Written Disclosure as a Treatment for Post-Traumatic Stress Disorder
This study will test the effectiveness of writing about a traumatic incident to treat post-traumatic stress disorder in people who have been in car accidents.
- Trial name
- NCT00862498
- Testing
- Written Disclosure
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Boston University
Anxiety, Depression Disorder
Effects of Mindfulness and Self-regulation Training on Anxiety, Depression, PTSD, and Leadership
The goal of this study is to measure the effects of Mindfulness-based Mind Fitness Training (MMFT) on anxiety, depression, post-traumatic stress disorder, sleep quality, and leadership.
- Conditions
- Anxiety, Depression Disorder, PTSD - Post Traumatic Stress Disorder
- Trial name
- NCT07084233
- Testing
- Mindfulness based, trauma informed, self-regulation skills training
- Where
- Ukraine
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Posttraumatic Stress Disorder
Telemental Health and Cognitive Processing Therapy for Rural Combat Veterans With Posttraumatic Stress Disorder
The immediate objective of this project was to evaluate the clinical effectiveness of a telemental health modality (video-teleconferencing) for providing an evidence-based group intervention (Cognitive Processing Therapy; CPT) to…
- Trial name
- CPTVTEL (NCT00879255)
- Testing
- Cognitive Processing Therapy Group Videoteleconference, Cognitive Processing Therapy Group In-Person
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- US Department of Veterans Affairs
Post-Traumatic Stress Disorder in Old Age
Memory Inhibition and Delayed Onset Post-traumatic Stress Disorder in Older Subjects
In the elderly, we can see a post-traumatic syndrome associated with an event that occurred before old age that had not previously manifested or not fully manifested.
- Trial name
- I-TSPT-R (NCT03897855)
- Testing
- Post Traumatic Stress Disorder
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier de Niort
Chronic Fatigue Syndrome, Fibromyalgia
Compare the Medical Conditions of Gulf War Veterans to Non-Deployed Veterans
Primary Hypothesis: Gulf War veterans will have an equal prevalence or mean level of the following medical and psychological conditions frequently reported in the literature compared to a control group of nondeployed veterans…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Post-Traumatic Stress Disorder, Neurologic Abnormalities
- Trial name
- NCT00032461
- Volunteers
- 2,000 people
- Sponsor
- US Department of Veterans Affairs
Stress Disorders, Posttraumatic
Stepped Preventive Care to Reduce the Impact of Acute Pediatric Injury
This study will evaluate the impact of a brief psychosocial intervention delivered to children or adolescents who are hospitalized for an unintentional injury.
- Trial name
- NCT00451282
- Testing
- stepped preventive care
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Children's Hospital of Philadelphia
PTSD
Group MDMA-therapy for Veterans With PTSD
This Phase 2a, open-label, non-randomized, 3-cohort study assesses the feasibility and safety of MDMA-assisted group therapy for the treatment of PTSD in veterans.
- Trial name
- Group-MVP (NCT05961527)
- Testing
- MDMA, Group Therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Portland VA Research Foundation, Inc