Clinical trials: Postural Instability, open to volunteers
Balance Impairment, Diabetic Neuropathy
Comparative Effects of Perturbation-Based Balance Training on Firm Surface and Rolling Board for Diabetic Neuropathy Patients
The present study is designed to compare the effectiveness of perturbation-based balance training performed on two different surfaces, stable (firm surface) and unstable (rolling board), for enhancing static, dynamic, and…
- Trial name
- NCT07598513
- Testing
- Group A (Perturbation Based Training on Firm Surface), Group B (Perturbation Based Training on Rolling Board)
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- University of Faisalabad
Parkinson Disease, Freezing of Gait
Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
The purpose of this study is to learn how brain signals are related to freezing of gait (FOG) and balance problems in Parkinson's disease (PD) and to study how different deep brain stimulation (DBS) settings may affect these…
- Trial name
- NCT07748962
- Testing
- Multiple Deep Brain Stimulation (DBS) Conditions, Moving Overground in a Virtual Environment (MOVE), Cleveland Clinic Stair Ambulation and Functional Evaluation of Gait (SAFE-Gait)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The Cleveland Clinic
Mild Traumatic Brain Injury, Concussion, Rehabilitation
Wearable Technology to Characterize and Treat mTBI Subtypes: Biofeedback-Based Precision Rehabilitation
Current clinical assessment tools are often not sensitive enough to detect and treat some subtle (yet troubling) problems after mTBI.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Rehabilitation, Balance Impairment
- Trial name
- SuBTyPE (NCT06381674)
- Testing
- Vestibular therapy for mTBI augmented with audio and visual real-time biofeedback, Vestibular therapy for mTBI
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Proprioception, Postural Balance, Performance
Effects of Pilates Training on Ankle Proprioception, Postural Control and Performance in Footballers With Chronic Ankle Instability
This study aims to contribute to the effects of Pilates training on ankle proprioception, postural control, and performance in football players with chronic ankle instability.
- Conditions
- Proprioception, Postural Balance, Performance, Chronic Ankle Instability, CAI
- Trial name
- CAI (NCT07266649)
- Testing
- Pilates exercises, Balance exercises
- Volunteers
- 88 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Chronic Ankle Instability, CAI
Radiological and Clinical Measures as Predictors of Dynamic Postural Control Deficits in Chronic Ankle Instability
The purpose of this study is to investigate the association between dynamic postural control and clinical measures of (ankle and hip strength, ankle DFROM and position sense) and radiological measures in patients with unilateral…
- Trial name
- NCT07051018
- Volunteers
- 50 people
- Sponsor
- Cairo University
Fall Prevention in Healthy Aging, Fall
Effect of LiFE-SePBT on Postural Stability in Community-dwelling Older Adults: an Assessor-blinded Randomised Controlled Trial
This study is an assessor-blinded randomised controlled trial investigating the effects of combined Lifestyle-integrated Functional Exercise and Self-initiated Perturbation-based Balance Training (LiFE-SePBT) on postural…
- Conditions
- Fall Prevention in Healthy Aging, Fall, Fall Prevention Training, Postural Control
- Trial name
- LiFE-SePBT (NCT07842094)
- Testing
- Lifestyle-integrated Functional Exercise, Upper limb mobilisation and flexibility training
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- The Hong Kong Polytechnic University
Ankle Sprains, Ankle Sprain Strain
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition after lateral ankle sprain. CAI is characterized by mechanical and/or functional instability, or recurrent episodes of "giving way," persisting for at least 12 months after…
- Conditions
- Ankle Sprains, Ankle Sprain Strain, Ankle Inversion Sprain
- Trial name
- NCT07728526
- Testing
- Postural Stabilization Training, Vestibulo-Ocular Reflex Exercise in addition to Postural Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bahçeşehir University
Flexible Flatfoot, Knee Pain
Effects of Short Foot Exercise on Knee Pain, Muscle Tone, Balance, and Quality of Life in Flexible Flatfoot Patients
This study was a clinical trial to investigate the effects of Short Foot Exercise (SFE) and standard physical therapy on knee muscle tone, knee pain and function, balance ability, and quality of life in adults with flexible flat…
- Conditions
- Flexible Flatfoot, Knee Pain, Balance Impairment, Quality of Life (QOL)
- Trial name
- NCT06861322
- Testing
- Short Foot Exercise, Conventional Physical Therapy
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Sahmyook University
Down Syndrome, Balance Impairment
Vestibular Stimulation Versus Foot Intrinsic Muscle Exercises in Children With Down Syndrome
This study will compare the effects of vestibular stimulation exercises and foot intrinsic muscle exercises on balance and functional mobility in children with Down syndrome aged 4-15 years.
- Conditions
- Down Syndrome, Balance Impairment, Functional Mobility
- Trial name
- VESTIB-FIME (NCT07778654)
- Testing
- Vestibular Stimulation Exercises, Foot Intrinsic Muscle Exercises
- Volunteers
- 48 people
- Sponsor
- Shalamar Institute of Health Sciences
Chronic Ankle Instability, CAI
Effects of Cervical and Oculomotor Exercises on Functional Status, Balance, and Proprioception in Chronic Ankle Instability
Effects of Cervical and Oculomotor Exercises on Functional Status, Balance, and Proprioception in Chronic Ankle Instability
- Trial name
- NCT07581535
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Izmir Katip Celebi University
Multiple Sclerosis, Parkinson Disease
Gait and Balance Impairment in Rare and Very Rare Neurological Diseases
Rare and very rare neurological diseases primarily or exclusively affect the nervous system with a prevalence of < 5 out of 10'000 and 100'000 people, respectively.
- Conditions
- Multiple Sclerosis, Parkinson Disease, Peripheral Neuropathy, Rare Diseases
- Trial name
- GALVANISE (NCT06343558)
- Testing
- Questionnaires, clinical scales and instrumental tests
- Where
- 2 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Parkinsons Disease
First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)
This study is researching an experimental drug called ALN-SNCA (called "study drug"). The study is focused on people with early Parkinson's disease, a disorder of the nervous system that affects movement.
- Trial name
- NCT07216066
- Testing
- ALN-SNCA
- Where
- 3 sites in Canada, Netherlands
- Volunteers
- 46 people
- Sponsor
- Regeneron Pharmaceuticals
Degenerative Cervical Myelopathy
Stimulation-based Therapy to Improve Balance in DCM
The goal of this clinical trial is to determine if a treatment called transcutaneous spinal cord stimulation (tSCS), when combined with balance training, can help improve balance in adults who have had surgery for degenerative…
- Trial name
- STIM-DCM (NCT07298460)
- Testing
- Transcutaneous spinal cord stimulation, Balance and Gait Training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Medical College of Wisconsin
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Adults With Parkinson's Disease
Neuromodulation for Patients With Parkinson's Disease
This study will compare different treatment schedules of combined transcranial direct current stimulation (tDCS) and transcranial ultrasound stimulation (TUS) in participants with Parkinson's disease.
- Trial name
- NCT07767006
- Testing
- tDCS combined with TUS
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Felipe Fregni, MD, PhD, MPH
Balance Impairment, Accidental Fall
Examining the Feasibility of an Outdoor Therapeutic Horse Carriage As a Perturbation -based Balance Training
The proposed study is a prospective experimental single-arm pre-post study aiming to assess the effectiveness and feasibility of an outdoor therapeutic horse carriage, i.e., the Equine Dynamic Balance (EDB), as a form of reactive…
- Trial name
- NCT06708104
- Testing
- Outdoor horse-assisted perturbation training
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loewenstein Hospital
Stroke
Effects of Core Strengthening With Pelvic Proprioceptive Neuromuscular Facilitation on Trunk Control and Balance in Patients With Sub-acute Stroke
Purpose of this study was to investigate the effectiveness of core stabilization with pelvic proprioceptive neuromuscular facilitation on trunk control and balance which will be provided an evidence-based selection of the best…
- Trial name
- NCT07381491
- Testing
- Core stabilization exercises, PNF, Trunk control exercises
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Stroke, Hemiplegia
Pelvic-Restricted vs. Pelvic-Free Robot-Assisted Gait Training in Stroke Patients
This randomized controlled clinical trial aims to compare the effects of pelvic-free versus pelvic-restricted robot-assisted gait training (RAGT) on gait pattern, balance, and fear of falling in stroke patients.
- Conditions
- Stroke, Hemiplegia, Gait Disorder, Sensorimotor, Balance Impairment
- Trial name
- NCT07365384
- Testing
- RoboGait® Pelvic-Free Mode, RoboGait® Pelvic-Restricted Mode, Conventional Rehabilitation
- Volunteers
- 36 people
- Sponsor
- Meltem Gunes Akinci
Parkinson's Disease
Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease
Balance problems and falls are among the most common complaints in Veterans with Parkinson's Disease (PD), but there are no effective treatments and the ability to measure balance and falls remains quite poor.
- Trial name
- NCT06405334
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Peripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater
Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity
The goal of this clinical trial is to investigate whether sensory stimulations from a neuroprosthesis device (Walkasins®) can increase physical activity and improve gait quality in persons with peripheral neuropathy (PN).
- Conditions
- Peripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater, Balance, Balance Impairment, Gait Disorders, Fatigue
- Trial name
- NCT07554443
- Testing
- External, lower limb sensory prosthesis
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- RxFunction Inc.