Clinical trials: Postviral Fatigue
Chronic Fatigue Syndrome in Adolescence, Postural Orthostatic Tachycardia Syndrome
POTS-CFS Study: Orthostatic Intolerance in the Context of Pediatric ME/CFS
Pilot-case-control study on exertion and orthostatic intolerance of adolescents with myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) compared to age-matched healthy controls (HC).
- Conditions
- Chronic Fatigue Syndrome in Adolescence, Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance
- Trial name
- POTS-CFS (NCT06054958)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Gulf War Syndrome, Chronic Fatigue Syndrome
Hyporeactivity and Gulf War Illness
This research project is a follow-up to the prior VA-funded study that found that chronic fatigue reported by many Gulf War veterans may be a symptom of dysfunctional cardiovascular stress response regulation.
- Conditions
- Gulf War Syndrome, Chronic Fatigue Syndrome, Post-Traumatic Stress Disorder
- Trial name
- NCT00100412
- Testing
- Graded dobutamine infusions, Graded phenylephrine injections, Psychosocial challenge involving socioevaluative public speaking
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Chronic Fatigue Syndrome
Efficacy and Safety of Fermented Velvet Antler Extract on Fatigue Recovery After Exercise
The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Fermented Velvet Antler extract on fatigue recovery after exercise.
- Trial name
- NCT01689467
- Testing
- Fermented Velvet Antler extract
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Gastrointestinal Diseases, Chronic Pain
Web-Based Survey of Pain, Stress and Complementary and Alternative Medicine
The investigators are inviting people with fibromyalgia, IBS, interstitial cystitis, chronic pain, and other chronic and recurring conditions to sign up and participate in a year-long Internet-based survey to study the…
- Conditions
- Gastrointestinal Diseases, Chronic Pain, Stress, Anxiety
- Trial name
- PROCAIM (NCT00740233)
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chronic Fatigue Syndrome
Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFS
Use of Viagra to Alter Symptoms in Patients with Chronic Fatigue Syndrome (CFS)
- Trial name
- NCT00598585
- Testing
- Sildenafil (Viagra)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Chronic Fatigue Syndrome, Cognitive Impairments
Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
Over the past decade, the Rochester Center for Behavioral Medicine (RCBM) has evaluated many patients with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT01071044
- Testing
- Lisdexamfetamine Dimesylate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Chronic Fatigue Syndrome
Cytokine Inhibition in Chronic Fatigue Syndrome Patients
Rationale: Chronic fatigue syndrome (CFS) is a medically unexplained syndrome for which no somatic or pharmacological treatment has been proven effective.
- Trial name
- CiCFS (NCT02108210)
- Testing
- Anakinra
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Acupressure, Fatigue Syndrome, Chronic
The Effect of Acupressure on Fatigue in Individuals With Chronic Fatigue Syndrome
Chronic fatigue syndrome is a common problem in society. The treatment of this problem is limited. Acupressure is a treatment method that has become widespread and promising in recent years.
- Conditions
- Acupressure, Fatigue Syndrome, Chronic, Complementary Therapies, Quality of Life
- Trial name
- NCT04435002
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Chronic Fatigue Syndrome
Epstein-Barr Virus as a Possible Cause for Chronic Fatigue Syndrome
The purpose of this study is to understand what causes a continuing fatigue for a long time with a number of symptoms occurring at the same time (Chronic Fatigue Syndrome-CFS).
- Trial name
- NCT00433355
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The Effect of Acupuncture Therapy on Cognitive Function in Post-COVID-19 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Background of study: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a common sequela after SARS-CoV-2 infection(COVID-19). Cognitive dysfunction is one of the most common debilitating symptoms in ME/CFS.
- Trial name
- NCT07357688
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Xi Wu
Chronic Fatigue Syndrome, Long COVID
Endothelial Dysfunction in Post-infection Fatigue Syndromes
Post-infection chronic fatigue syndromes, such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID-19 condition (Long Covid), are conditions primarily characterized by debilitating fatigue.
- Trial name
- NCT06463106
- Where
- Austria
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Autoimmunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
This study investigates whether there is an immune response directed against gut microbes or food and parts of the body in severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) patients.
- Trial name
- NCT03254823
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Chronic Fatigue Syndrome., Muscular Diseases.
Clinical Trial to Evaluate the Effectiveness of Acupuncture as a Treatment in Patients Diagnosed With CFS.
background: The Chronic Fatigue Syndrome (CFS) presents many disturbances multidimensional affect holistically to people who have the disease and current management of fatigue, pain, anxiety, depression and sleep disturbances…
- Conditions
- Chronic Fatigue Syndrome., Muscular Diseases., Cognitive Impairment, Sleep Disturbances
- Trial name
- AV/AS (NCT01907711)
- Testing
- Acupuncture.
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Vall d'Hebron
Post-Acute COVID-19 Vaccination Syndrome, Postviral Fatigue
Clinical Laboratory Evaluation, Assessment of Symptoms and Recovery in Patients With Post-COVID-19-Vaccination Syndrome
Some people report persistent health problems after receiving the COVID-19 vaccine. These symptoms persist well beyond typical short-term vaccine side effects and are not attributable to any other known medical conditions.
- Trial name
- CLEAR (NCT07400848)
- Testing
- Blood sampling and analysis, The continuous Reactive Hyperemia Index (InRHI) measured by EndoPAT
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bern
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Cardiopulmonary Testing in ME/CFS to Improve Diagnostic Accuracy
Circumstantial evidence suggests that patients diagnosed with myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) perform worse on day 2 in a 2-day consecutive cardiopulmonary exercise test (CPET).
- Trial name
- NCT02970240
- Testing
- Cardiopulmonary testing
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Postcancer Fatigue, Chronic Fatigue Syndrome
Humoral and Cellular Immune Responses After Influenza Vaccination in Patients With Postcancer Fatigue and in Patients With Chronic Fatigue Syndrome
Postcancer fatigue (PCF) is a frequently occurring, severe and invalidating problem, impairing quality of life. Patients with chronic fatigue syndrome (CFS) also suffer from severe fatigue symptoms.
- Trial name
- NCT01651754
- Testing
- Seasonal influenza vaccination
- Where
- Netherlands
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Fibromyalgia, Irritable Bowel Syndrome
Patient-reported Outcome Measures (PROMs) in Patients With Bodily Stress Syndrome: Protocol for a Prospective Cohort Study
This cohort study implements patient reported outcome measures (PROMs) for patients with bodily stress syndrome in a clinic for functional disorders.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Somatic Symptom, Chronic Fatigue Syndrome
- Trial name
- SYMPA (NCT04667611)
- Testing
- Psychosocial interventions
- Where
- Finland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Chronic Fatigue Syndrome, Orthostatic Intolerance
Autonomic Nervous System and Chronic Fatigue Syndrome
The investigators propose to test the hypothesis that the sympathetic nervous system contributes to the cardiovascular and inflammatory abnormalities present in the chronic fatigue syndrome (CFS) and, in particular in the subset…
- Conditions
- Chronic Fatigue Syndrome, Orthostatic Intolerance, Postural Tachycardia Syndrome
- Trial name
- CFS&ANS (NCT00580619)
- Testing
- Autonomic Function Testing, Saline infusions, L-NMMA trimethaphan
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Analysis of Post-exertional Malaise Using a Two-day CPET in People With ME/CFS
This study aims to collect and identify key outcome measures or disease parameters in ME/CFS that are altered during elevated symptoms relative to baseline by gathering information before and after symptom provocation using a…
- Trial name
- NCT04026425
- Testing
- Two-day cardiopulmonary exercise test
- Where
- 3 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Ithaca College
Chronic Fatigue Syndrome
Structural Problems in Brainstem and Cervical Spine Cord in ME/CFS
A case control study on patients with ME/CFS and healthy controls on prevalence of cervical obstructions, Cerebro spinal fluid (CSF) pressure and laboratory findings.
- Trial name
- NCT04403854
- Testing
- MRI, Spinal Tap
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bragee Clinics