Clinical trials: Pouches, Ileoanal
Pouchitis, Pouches, Ileoanal
Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch
The goal of this clinical trial is to learn if mirikizumab works to treat pouch disorders in adults. The main questions it aims to answer are: Does mirikizumab reduce symptoms of pouch disorders Participants will: Take…
- Conditions
- Pouchitis, Pouches, Ileoanal, Pouch, Ileal
- Trial name
- NCT06864403
- Testing
- Mirikizumab - Intravenous (IV), Mirikizumab - Subcutaneous (SC)
- Where
- 5 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Pouches, Ileoanal
Artificial Intelligence in Image Recognition of Pouchoscopies in Patients With Restorative Proctocolectomy
The application of artificial intelligence in pouchoscopy of patients with restorative proctocolectomy might improve the diagnosis of pouchitis and neoplasms.
- Trial name
- PouchVision (NCT04864587)
- Testing
- Artificial intelligence used for image recognition in pouchoscopy
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Theresienkrankenhaus und St. Hedwig-Klinik GmbH
Crohn's Disease, Fistula
Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's
The purpose of this study is to determine the safety and feasibility of using allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat people with an ileal pouch anal anastomosis (IPAA) who develop a fistula in the…
- Conditions
- Crohn's Disease, Fistula, Anal Fistula, Pouch, Ileal
- Trial name
- IPAAF (NCT04073472)
- Testing
- mesenchymal stem cells (MSCs)
- Sponsor
- The Cleveland Clinic
Familial Adenomatous Polyposis (FAP), Pouches, Ileoanal
Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL)
This international, multi-centre randomised controlled trial will compare dye-based chromoendoscopy with virtual chromoendoscopy, using NBI/BLI, for adenoma detection during routine surveillance pouchoscopy in adults with…
- Trial name
- ENDOPOL (NCT07726771)
- Testing
- Chromoendoscopy (Indigo Carmine), Virtual Chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- London North West Healthcare NHS Trust
Pouch, Ileal, Pouches, Ileoanal
Tirzepatide for Ileal Pouch-anal Anastomosis (IPAA) and Chronic High Bowel Frequency (I8F-NS-X008)
The goal of this clinical trial is to learn if Tirzepatide (Zepbound) can decrease bowel frequency in patients that have an ileal-pouch anal anastomosis (IPAA or pouch) better than standard of care anti-diarrheal therapy.
- Conditions
- Pouch, Ileal, Pouches, Ileoanal, Bowel Diseases, Inflammatory
- Trial name
- PROP-ZEP (NCT07756359)
- Testing
- Tirzepatide, Loperamide, Diphenoxylate/Atropine
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Colonic Pouches, Physical Therapy Modalities
Rehabilitation After Ileo-anal Pouch Surgery
Multi-centre, assessor-blinded, randomised controlled trial comparing physiotherapist-led behavioural intervention (including pelvic floor muscle training) to standard care, in the management of post-operative ileo-anal pouch…
- Conditions
- Colonic Pouches, Physical Therapy Modalities, Biofeedback
- Trial name
- RAP (NCT03148600)
- Testing
- Pelvic floor and bowel behavioural training, Standard arm
- Where
- 2 sites in Australia
- Volunteers
- 53 people
- Sponsor
- St Vincent's Hospital Melbourne