Clinical trials: Poverty
Infertility Assisted Reproductive Technology, Oocyte Retrieval
ART Cycle Outcomes When Only 1 to 3 Oocytes Are Retrieved
This is a monocentric retrospective observational study. The study focuses on the women who underwent Assisted Reproductive Technology (ART) cycles with poor ovarian response (POR), defined as <4 oocytes retrieved.
- Trial name
- POR (NCT06950476)
- Testing
- Oocyte Retrieval
- Volunteers
- 3,761 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Reproductive Health
Youth-friendly Sexual and Reproductive Healthcare Pilot in Mumbai, India
This study will systematically adapt, pilot test, and evaluate an integrated community/facility intervention to improve the uptake of adolescent-friendly services for married and unmarried adolescent girls and young women (AGYW…
- Trial name
- NCT04307849
- Testing
- Adolescent Health Club, Wait-list Control
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hepatitis B
Expression of Th9 Cells and Poor/Non-responsiveness to Hepatitis B Vaccination
An observational study will be performed in subjects aged 3-65 years old to describe the dynamic changes of cellular immunity after vaccination of hepatitis B vaccine, and to find out the expression levels of Th9 cells and IL9 in…
- Trial name
- NCT01441609
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Beijing Municipal Science & Technology Commission
Diabetes, Atherosclerosis Cardiovascular Disease
Social Engagement Strategies to Improve Medication Adherence
In this pilot study, investigators, in partnership with Resource Centers for Minority Aging Research (RCMAR) mentorship team and the MyMeds program, will enroll patients from MyMeds with diabetes, atherosclerotic cardiovascular…
- Conditions
- Diabetes, Atherosclerosis Cardiovascular Disease, Congestive Heart Failure, Poor Medication Adherence
- Trial name
- NCT03734887
- Testing
- Social Network Feedback, Private Feedback
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Orthopedic Disorder, Hip Arthropathy
Iron and Vitamin Supplementation in Hip/Knee Surgery
Randomized controlled trial to evaluate the efficacy of oral iron supplementation plus cofactors in reducing the prevalence of preoperative anemia in a cohort of 60 patients undergoing elective prosthetic hip or knee surgery.
- Conditions
- Orthopedic Disorder, Hip Arthropathy, Knee Arthropathy, Anemia
- Trial name
- NCT04880499
- Testing
- Iron plus folic acid, vitamin B2, B6, B12, C, and E
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
OVARIAN STIMULATION
Follicular Volume at the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation With Oocyte Maturity
Women with a severely diminished ovarian reserve and monofollicular growth are at a higher risk of premature ovulation as well as poor quality oocytes.
- Trial name
- NCT06839274
- Testing
- transvaginal Ultrasound
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
in Vitro Fertilization, Poor Responder
Dopamine D-2 Antagonist Use in Poor Responders in IVF: a Randomized Controlled Trial
Metoclopramide is a dopamine D2 receptor antagonist with antiemetic and gastrokinetic properties which has been approved for use in pregnant women.
- Trial name
- NCT02262923
- Testing
- metoclopramide
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Carcinoma of Unknown Primary
Pembrolizumab in Patients With Poor-Prognosis Carcinoma of Unknown Primary Site (CUP)
Abbreviated Title: Pembrolizumab in Patients with Poor-Prognosis Carcinoma of Unknown Primary Site (CUP) Trial Phase: 2 Clinical Indication: Treatment naïve patients with poor prognosis carcinoma of unknown primary site Trial…
- Trial name
- CUP (NCT03391973)
- Testing
- Pembrolizumab Injection
- Where
- 3 sites in Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- AHS Cancer Control Alberta
Alzheimer's Disease, Huntington's Disease
A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers
This study will evaluate the potential for a drug-drug interaction of Dimebon with ketoconazole and omeprazole, potent inhibitors of the drug metabolizing enzymes CYP3A4 and CYP2C19, respectively.
- Trial name
- NCT00931073
- Testing
- Dimebon alone, Dimebon + Ketoconazole, Dimebon + Omeprazole
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cardiovascular Diseases, Cardiovascular Risk Factor
Cardiovascular Health Awareness Program (CHAP) in Subsidized Social Housing
This project aims to improve the cardiovascular health of seniors living in subsidized housing by implementing the successful community-based Cardiovascular Health Awareness Program (CHAP).
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Diabetes Mellitus
- Trial name
- NCT03549845
- Testing
- Cardiovascular Health Awareness Program
- Where
- Canada
- Volunteers
- 2,742 people, healthy volunteers welcome
- Sponsor
- McMaster University
Opioid-use Disorder, Contraception
Averting NAS Among Opioid-Using Young Women Receiving MAT Using Buprenorphine
The primary objective of this study is to test the efficacy of a Motivational Interviewing and Educational Training intervention with immediate linkage to long acting reversible contraception (LARC) (hereafter known as MIET).
- Conditions
- Opioid-use Disorder, Contraception, Neonatal Abstinence Syndrome
- Trial name
- NAS-MIET (NCT04611659)
- Testing
- Motivational Interviewing and Educational Training (MIET)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Impaired Glucose Tolerance, Hyperinsulinism
Effect of Meal Frequency on Glycemic Control of People at High Risk or Diagnosed With Diabetes
This study investigated any potential associations between two isocaloric diets with different meal frequency (3 meals versus 6 meals) and glycemic control in people at high diabetes risk (lean and overweight/obese women with…
- Conditions
- Impaired Glucose Tolerance, Hyperinsulinism, Poor Glycemic Control, Hyperglycemia
- Trial name
- NCT02248272
- Testing
- Isocaloric diet with 3 meals, Isocaloric diet with 6 meals
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Meropi Kontogianni
Pregnancy, Eclampsia
A Cluster-Randomized Trial of Ultrasound Use to Improve Pregnancy Outcomes in Low Income Country Settings
In many low-income countries, the use of ultrasound by medical officers and non-physician health care staff (e.g., midwives) for antenatal identification of high risk pregnancies is a new intervention requiring authoritative…
- Conditions
- Pregnancy, Eclampsia, Placenta Previa, Stillbirth
- Trial name
- NCT01990625
- Testing
- Antenatal Ultrasound Scan
- Where
- 5 sites in Guatemala, Kenya and 3 more
- Volunteers
- 45,038 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Obese, Sleep Apnea, Obstructive
Eval EarlySense Bet Lowenstein Sleeplab
The study objective is to collect heart rate, respiration rate and motion data of patients admitted to sleep lab and to determine the accuracy level of the EarlySense system vs.
- Conditions
- Obese, Sleep Apnea, Obstructive, Central Apnea, Sleep Disorders
- Trial name
- NCT01978340
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- EarlySense Ltd.
Women With Poor Ovarian Response
GnRH Agonist Triggering Supplemented With Hcg in Women With Poor Ovarian Response
During the last decades, owing to the growing tendency of women to delay childbearing plans because of career and personal priorities, fertility specialists today are seeing more and more women with poor ovarian reserve and with…
- Trial name
- NCT02144818
- Testing
- Ovitrel, Decapeptyl
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ovarian Reserve
CD133 Transplantation to Generate Oocytes in Poor Ovarian Reserve
Women delay maternity and, as a consequence, available oocyte number and their quality decrease (9-18% of all IVF patients). Different treatment protocols have been developped nevertheless none of them optimal: the number of…
- Trial name
- NCT01966536
- Testing
- CD133+ cells transplantation into ovarian artery of one ovary
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Poor Quality Sleep
Efficacy of Different Types of Milk in Improving Sleep Quality in Subjects With Sleep Problems (Milca)
Randomized, controlled, double-blind intervention study, with four parallel branches depending on the product consumed, to analyze the efficacy of different types of milks on the improvement of sleep quality.
- Trial name
- Milca (NCT06154616)
- Testing
- Control Product, Experimental Product: 250, Experimental Product: 250 + TRP
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Leg Cramps, Nocturnal, Poor Sleep Quality
Weighted Blanket in Pregnancy
Pregnancy is frequently accompanied by sleep disturbances, musculoskeletal discomfort, anxiety, and stress, which may negatively affect maternal well-being and daily functioning.
- Conditions
- Leg Cramps, Nocturnal, Poor Sleep Quality, Pregnancy, Anxiety
- Trial name
- Weighted (NCT07309016)
- Testing
- Weighted Blanket
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Infertility
Long Protocol and Growth Hormone in Poor Responders
The long down regulation protocol is widely used in the in vitro fertilization cycles, now it will be assessed regarding its efficacy, in poor responder females undergoing in vitro fertilization cycles, alone and after the…
- Trial name
- NCT02338206
- Testing
- Growth hormone
- Where
- Egypt
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Healthy, Nutrition Poor
Effects of Lutein on Visual Function
Randomized, double blind, placebo-controlled intervention trial on the ocular benefits and inflammatory markers improvements of taking FloraGLO Lutein for 9 months.
- Trial name
- NCT03113864
- Testing
- Lutein
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC